ChemicalBook > CAS DataBase List > 4-METHYL-3-(TRIFLUOROMETHYL)BROMOBENZENE

4-METHYL-3-(TRIFLUOROMETHYL)BROMOBENZENE

Product Name
4-METHYL-3-(TRIFLUOROMETHYL)BROMOBENZENE
CAS No.
86845-27-4
Chemical Name
4-METHYL-3-(TRIFLUOROMETHYL)BROMOBENZENE
Synonyms
5-BROMO-2-METHYLBENZOTRIFLUORIDE;4-BROMO-2-(TRIFLUOROMETHYL)TOLUENE;5-Bromo-2-methylbenzotrifluoride98%;5-Bromo-2-methylbenzotrifluoride 98%;4-METHYL-3-(TRIFLUOROMETHYL)BROMOBENZEN;4-METHYL-3-(TRIFLUOROMETHYL)BROMOBENZENE;4-bromo-1-methyl-2-(trifluoromethyl)benzene;Benzene,4-broMo-1-Methyl-2-(trifluoroMethyl)-;4-Methyl-3-(trifluoromethyl)bromobenzene, 97+%;4-METHYL-3-(TRIFLUOROMETHYL)BROMOBENZENE86845-27-4
CBNumber
CB6190972
Molecular Formula
C8H6BrF3
Formula Weight
239.03
MOL File
86845-27-4.mol
More
Less

4-METHYL-3-(TRIFLUOROMETHYL)BROMOBENZENE Property

Boiling point:
181.8±35.0 °C(Predicted)
Density 
1 g/cm3
refractive index 
1.4870
storage temp. 
2-8°C
Appearance
Colorless to light yellow Liquid
InChI
InChI=1S/C8H6BrF3/c1-5-2-3-6(9)4-7(5)8(10,11)12/h2-4H,1H3
InChIKey
IZFVIEYHUOUPPH-UHFFFAOYSA-N
SMILES
C1(C)=CC=C(Br)C=C1C(F)(F)F
CAS DataBase Reference
86845-27-4(CAS DataBase Reference)
More
Less

Safety

Hazard Codes 
F
Risk Statements 
10-36/37/38
Safety Statements 
16-26-36
RIDADR 
1993
Hazard Note 
Flammable
HazardClass 
IRRITANT
PackingGroup 
III
HS Code 
2903998090
More
Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H227Combustible liquid

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P405Store locked up.

More
Less

N-Bromosuccinimide Price

TRC
Product number
B699063
Product name
4-Bromo-2-(trifluoromethyl)toluene
Packaging
100mg
Price
$45
Updated
2021/12/16
TRC
Product number
B699063
Product name
4-Bromo-2-(trifluoromethyl)toluene
Packaging
250mg
Price
$55
Updated
2021/12/16
BroadPharm
Product number
BP-20386
Product name
4-METHYL-3-(TRIFLUOROMETHYL)BROMOBENZENE
Purity
96%
Packaging
1g
Price
$20
Updated
2021/12/16
Matrix Scientific
Product number
054612
Product name
5-Bromo-2-methylbenzotrifluoride
Purity
98%
Packaging
5g
Price
$38
Updated
2021/12/16
SynQuest Laboratories
Product number
1800-B-59
Product name
5-Bromo-2-methylbenzotrifluoride
Purity
98%
Packaging
1g
Price
$68
Updated
2021/12/16
More
Less

4-METHYL-3-(TRIFLUOROMETHYL)BROMOBENZENE Chemical Properties,Usage,Production

Synthesis

65934-74-9

86845-27-4

Under nitrogen protection, 2642.3 g of a 48% aqueous solution of hydrogen bromide was added to the reactor. The temperature of the system was adjusted to 30 °C, followed by the slow dropwise addition of 1760.0 g of a mixed solution of water and 880.0 g of acetic acid while stirring. Next, 880.0 g of 2-methyl-5-aminobenzotrifluoride (isomer content 0.037%, determined by gas phase area normalization) was added. After the dropwise addition, the reaction temperature was raised to 95 °C with continuous stirring for 30 min to obtain the corresponding hydrogen bromide salt solution. The reaction solution was cooled to 0 °C, at which temperature 1213.3 g of a 30% aqueous sodium nitrite solution was slowly added dropwise. After completion of the dropwise addition, the reaction was continued for 1.0 hour to ensure complete reaction. The prepared diazonium salt solution was slowly added dropwise at 65 °C to a pre-prepared mixture containing 360.4 g of copper bromide and 4997.0 g of 48% aqueous hydrogen bromide. A large amount of nitrogen release was observed during the reaction. After dropwise addition, stirring was continued for 1 hour to obtain a solution of 4-bromo-1-methyl-2-(trifluoromethyl)benzene. At the end of the reaction, the reaction solution was cooled to 20 °C, stirred for 1.0 h and left to stratify. 1046.0 g of the organic layer was separated and 3661.0 g of water was added and the pH was adjusted with 5.0% alkali metal hydroxide solution to 7. Subsequent steam distillation afforded 1032.0 g of a pale yellow 4-bromo-1-methyl-2-(trifluoromethyl)benzene product in 85.9% yield and 99.2% gas phase purity. Gas chromatographic analysis showed that the isomer content in the product was less than 0.1%.

References

[1] Patent: CN107915570, 2018, A. Location in patent: Paragraph 0057-0061; 0064-0067

4-METHYL-3-(TRIFLUOROMETHYL)BROMOBENZENE Preparation Products And Raw materials

Raw materials

Preparation Products

More
Less

4-METHYL-3-(TRIFLUOROMETHYL)BROMOBENZENE Suppliers

Belgium 1 China 105 France 2 Germany 5 India 3 Italy 1 The Netherlands 1 United Kingdom 7 United States 18 Global 143
Ark Pharm, Inc.
Tel
847-367-3680
Fax
847-367-3681
Email
sales@arkpharminc.com
Country
United States
ProdList
1670
Advantage
56
Accela ChemBio Inc.
Tel
+1-858-6993322
Fax
(+1)-858-876-1948
Email
info@accelachem.com
Country
United States
ProdList
21193
Advantage
58
Alchem Pharmtech,Inc.
Tel
8485655694
Email
sales@alchempharmtech.com
Country
United States
ProdList
63687
Advantage
58
Aladdin Scientific
Tel
Email
tp@aladdinsci.com
Country
United States
ProdList
57505
Advantage
58
Synthonix Inc
Tel
--
Fax
--
Email
info@synthonix.com
Country
United States
ProdList
6872
Advantage
58
Oakwood Products, Inc.
Tel
--
Fax
--
Email
sales@oakwoodchemical.com
Country
United States
ProdList
6193
Advantage
74
Fluorochem Ltd.
Tel
--
Fax
--
Email
enquiries@fluorochem.co.uk
Country
United States
ProdList
4583
Advantage
58
Alichem Inc.
Tel
--
Fax
--
Email
sales@alichem.com
Country
United States
ProdList
6167
Advantage
58
Combi-Blocks, Inc.
Tel
--
Fax
--
Email
les@combi-blocks.com
Country
United States
ProdList
2555
Advantage
58
Chemphtec Corporation
Tel
--
Fax
--
Email
fo@chemphtec.com
Country
United States
ProdList
2181
Advantage
58
AK Scientific, Inc.
Tel
--
Fax
--
Email
sales@aksci.com
Country
United States
ProdList
6347
Advantage
65
VWR International, LLC.
Tel
--
Fax
--
Email
@sargentwelch.com
Country
United States
ProdList
6262
Advantage
58
Combi-Blocks Inc.
Tel
--
Fax
--
Email
sales@combi-blocks.com
Country
United States
ProdList
6618
Advantage
69
SynQuest Laboratories, Inc.
Tel
--
Fax
--
Email
info@synquestlabs.com
Country
United States
ProdList
6871
Advantage
62
Matrix Scientific
Tel
--
Fax
--
Email
sales@matrixscientific.com
Country
United States
ProdList
6632
Advantage
80
Alfa Aesar
Tel
--
Fax
--
Email
tech@alfa.com
Country
United States
ProdList
6814
Advantage
81
INDOFINE Chemical Company, Inc.
Tel
--
Fax
--
Email
chemical@indofinechemical.com
Country
United States
ProdList
6176
Advantage
69
3B Scientific Corporation
Tel
--
Fax
--
Email
sales@3bsc.com
Country
United States
ProdList
6718
Advantage
47
More
Less

View Lastest Price from 4-METHYL-3-(TRIFLUOROMETHYL)BROMOBENZENE manufacturers

Career Henan Chemical Co
Product
4-METHYL-3-(TRIFLUOROMETHYL)BROMOBENZENE 86845-27-4
Price
US $0.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
kg/T
Release date
2019-12-18

86845-27-4, 4-METHYL-3-(TRIFLUOROMETHYL)BROMOBENZENERelated Search:

2-Methylbenzotrifluoride Toluene 2-METHYL-5-(TRIFLUOROMETHYL)BROMOBENZENE 2-METHYL-3-(TRIFLUOROMETHYL)BROMOBENZENE 4-Methyl-2-(trifluoromethyl)bromobenzene, 97+% 3-METHYL-5-(TRIFLUOROMETHYL)BROMOBENZENE 2-Methyl-5-(trifluoromethyl)bromobenzene, 97+% 4-METHYL-2-(TRIFLUOROMETHYL)BROMOBENZENE

  • 4-METHYL-3-(TRIFLUOROMETHYL)BROMOBENZENE
  • 4-BROMO-2-(TRIFLUOROMETHYL)TOLUENE
  • 5-BROMO-2-METHYLBENZOTRIFLUORIDE
  • 4-Methyl-3-(trifluoromethyl)bromobenzene, 97+%
  • 5-Bromo-2-methylbenzotrifluoride 98%
  • 5-Bromo-2-methylbenzotrifluoride98%
  • 4-bromo-1-methyl-2-(trifluoromethyl)benzene
  • 4-METHYL-3-(TRIFLUOROMETHYL)BROMOBENZENE86845-27-4
  • Benzene,4-broMo-1-Methyl-2-(trifluoroMethyl)-
  • 4-METHYL-3-(TRIFLUOROMETHYL)BROMOBENZEN
  • 86845-27-4
  • Trifluoromethylbenzene serise