AC-DEVD-PNA

Product Name: AC-DEVD-PNA
CAS No.: 189950-66-1
Chemical Name: AC-DEVD-PNA
Synonyms: AC-DEVD-P;AC-DEVD-PNA;(2S,5S,8S,11S);ACETYL-DEVD-PNA;AC-DEVD-PNA?, >98%;-11-(carboxymethyl);-8-(2-carboxyethyl);AC-ASP-GLU-VAL-ASP-PNA;-2-(2-Amino-2-oxoethyl);N-Ac-Asp-Glu-Val-Asp-pNA
CBNumber: CB6203612
Molecular Formula: C26H34N6O13
Formula Weight: 638.58
MOL File: 189950-66-1.mol

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AC-DEVD-PNA Property

Boiling point:: 1191.1±65.0 °C(Predicted)
Density: 1.448±0.06 g/cm3(Predicted)
storage temp.: -20°C
solubility: DMSO (Slightly), Methanol (Slightly, Heated)
pka: 2.97±0.10(Predicted)
form: powder
color: white
Water Solubility: Soluble in water (partly), dimethyl sulfoxide, buffer, pH 7, and acetonitrile:methanol (1:1) (1 mg/ml).
Stability:: Hygroscopic

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Safety

WGK Germany: 3

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: A2559
Product name: N-Acetyl-Asp-Glu-Val-Asp p-nitroanilide
Purity: ≥97% (HPLC), powder
Packaging: 5mg
Price: $203
Updated: 2024/03/01

Alfa Aesar

Product number: J65878
Product name: N-Acetyl-Asp-Glu-Val-Asp p-nitroanilide
Packaging: 25mg
Price: $321
Updated: 2023/06/20

Cayman Chemical

Product number: 14460
Product name: Ac-DEVD-pNA
Purity: ≥95%
Packaging: 1mg
Price: $25
Updated: 2021/12/16

Cayman Chemical

Product number: 14460
Product name: Ac-DEVD-pNA
Purity: ≥95%
Packaging: 5mg
Price: $69
Updated: 2021/12/16

Cayman Chemical

Product number: 14460
Product name: Ac-DEVD-pNA
Purity: ≥95%
Packaging: 10mg
Price: $125
Updated: 2021/12/16

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AC-DEVD-PNA Chemical Properties,Usage,Production

Uses

N-Acetyl-L-α-aspartyl-L-α-glutamyl-L-valyl-N-(4-nitrophenyl)-L-asparagine is an para-nitro aniline chromophore cleaved by caspase.

Uses

N-Acetyl-Asp-Glu-Val-Asp p-nitroanilide is an chromogenic substrate for Caspase 3 and CCP-32.

Uses

N-Acetyl-Asp-Glu-Val-Asp p-nitroanilide has been used as a chromogenic substrates for determining caspase-3 and caspase-8 activities in liver tissue homogenates and caspase 3 activity in aortic vascular smooth muscle cells and neuroblastoma cell lines.

Biochem/physiol Actions

Colorimetric substrate for caspase 3, a protease that is rapidly activated when cells are exposed to apoptotic conditions and that cleaves poly(ADP-ribose) polymerase.

AC-DEVD-PNA Preparation Products And Raw materials

Raw materials

Preparation Products

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AC-DEVD-PNA Suppliers

Canada 1 China 83 France 1 Germany 1 India 1 Japan 3 Switzerland 2 United Kingdom 4 United States 20 Global 116

J & K SCIENTIFIC LTD.

Tel: 010-82848833 400-666-7788
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Beijing Ouhe Technology Co., Ltd

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VDM Biochemicals

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Shanghai Hanhong Scientific Co.,Ltd.

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Chemsky（shanghai）International Co.,Ltd.

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Cellmano Biotech Limited

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Shanghai Aladdin Bio-Chem Technology Co.,LTD

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MedChemexpress LLC

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Sigma-Aldrich

Tel: 021-61415566 800-8193336
Email: orderCN@merckgroup.com
Country: China
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189950-66-1, AC-DEVD-PNARelated Search:

2-AMINO-9H-PYRIDO[2,3-B]INDOLE ACA N-acetyl aspartyl-glutaMic acid ALA-ALA-VAL-ALA P-NITRO-ANILIDE AC-ASP-PNA VAL-ALA P-NITROANILIDE ACETATE SALT H-VAL-ALA-PNA 4-(4-AMINOANILINO)-4-OXOBUTANOIC ACID AC-DEVD-PNA AC-DEVD-CHO SUC-ALA-ALA-ALA-PNA

CASPASE 3 (APOPAIN) SUBSTRATE 1, CHROMOGENIC

CASPASE-3 SUBSTRATE VIII, WATER-SOLUBLE, COLORIMETRIC

CASPASE 3/CPP32 CHROMOGENIC SUBSTRATE

CASPASE-3 SUBSTRATE (CHROMOGENIC)

CASPASE-3 SUBSTRATE I, COLORIMETRIC

CHROMOGENIC CASPASE 3 SUBSTRATE AC-DEVD-PNA

AC-ASP-GLU-VAL-ASP-PARANITROANILIDE

AC-ASP-GLU-VAL-ASP-PNA

AC-DEVD-PNA

ACETYL-DEVD-PNA

ACETYL-ASP-GLU-VAL-ASP-(P-NITROANILIDE)

N-ACETYL-ASP-GLU-VAL-ASP-P-NITROANILIDE

N-ACETYL-ASP-GLU-VAL-ASP-P-NITROANILIDE PNA

AC-ASP-GLU-VAL-ASP-P-NITROANILIDE

AC-ASP-GLU-VAL-ASP-PNA: AC-DEVD-PNA

Ac-DEVD-pNA(Caspase-3 Substrate)

Ac-DEVD-pNA,N-Acetyl-Asp-Glu-Val-Asp-p-Nitroanilide, >98%

AC-DEVD-PNA?, >98%

(2S,5S,8S,11S)

-11-(carboxymethyl)

-2-(2-Amino-2-oxoethyl)

-4,7,10,13-tetraoxo-3,6,9,12-tetraazatetradecan-1-oic acid

-5-isopropyl-3-(4-nitrophenyl)

-8-(2-carboxyethyl)

N-Acetyl-L-α-aspartyl-L-α-glutamyl-L-valyl-N-(4-nitrophenyl)-L-asparagine

Ac-DEVD-pNA，Ac-Asp-Glu-Val-Asp-pNA，Ac-Asp-Glu-Val-Asp-p-nitroanilide

L-Asparagine, N-acetyl-L-α-aspartyl-L-α-glutamyl-L-valyl-N-(4-nitrophenyl)- (9CI)

AC-DEVD-P

N-Acetyl-L-a-aspartyl-L-a-glutamyl-L-valyl-N-(4-nitrophenyl)-L-asparagine

Ac-DEVD-pNA，N-Acetyl-Asp-Glu-Val-Asp-p-Nitroanilide

N-Ac-Asp-Glu-Val-Asp-pNA

189950-66-1

C26H34N6O13

Substrates

BioChemical

Caspase 3

Caspases

Cell Biology

Cell Signaling and Neuroscience

Apoptosis and Cell Cycle

Caspase/Related Products

Pepetides

peptide