ChemicalBook > CAS DataBase List > AC-DEVD-PNA

AC-DEVD-PNA

Product Name
AC-DEVD-PNA
CAS No.
189950-66-1
Chemical Name
AC-DEVD-PNA
Synonyms
AC-DEVD-P;AC-DEVD-PNA;(2S,5S,8S,11S);ACETYL-DEVD-PNA;AC-DEVD-PNA?, >98%;-11-(carboxymethyl);-8-(2-carboxyethyl);AC-ASP-GLU-VAL-ASP-PNA;-2-(2-Amino-2-oxoethyl);N-Ac-Asp-Glu-Val-Asp-pNA
CBNumber
CB6203612
Molecular Formula
C26H34N6O13
Formula Weight
638.58
MOL File
189950-66-1.mol
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AC-DEVD-PNA Property

Boiling point:
1191.1±65.0 °C(Predicted)
Density 
1.448±0.06 g/cm3(Predicted)
storage temp. 
-20°C
solubility 
DMSO (Slightly), Methanol (Slightly, Heated)
pka
2.97±0.10(Predicted)
form 
powder
color 
white
Water Solubility 
Soluble in water (partly), dimethyl sulfoxide, buffer, pH 7, and acetonitrile:methanol (1:1) (1 mg/ml).
Stability:
Hygroscopic
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Safety

WGK Germany 
3
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
A2559
Product name
N-Acetyl-Asp-Glu-Val-Asp p-nitroanilide
Purity
≥97% (HPLC), powder
Packaging
5mg
Price
$203
Updated
2024/03/01
Alfa Aesar
Product number
J65878
Product name
N-Acetyl-Asp-Glu-Val-Asp p-nitroanilide
Packaging
25mg
Price
$321
Updated
2023/06/20
Cayman Chemical
Product number
14460
Product name
Ac-DEVD-pNA
Purity
≥95%
Packaging
1mg
Price
$25
Updated
2021/12/16
Cayman Chemical
Product number
14460
Product name
Ac-DEVD-pNA
Purity
≥95%
Packaging
5mg
Price
$69
Updated
2021/12/16
Cayman Chemical
Product number
14460
Product name
Ac-DEVD-pNA
Purity
≥95%
Packaging
10mg
Price
$125
Updated
2021/12/16
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AC-DEVD-PNA Chemical Properties,Usage,Production

Uses

N-Acetyl-L-α-aspartyl-L-α-glutamyl-L-valyl-N-(4-nitrophenyl)-L-asparagine is an para-nitro aniline chromophore cleaved by caspase.

Uses

N-Acetyl-Asp-Glu-Val-Asp p-nitroanilide is an chromogenic substrate for Caspase 3 and CCP-32.

Uses

N-Acetyl-Asp-Glu-Val-Asp p-nitroanilide has been used as a chromogenic substrates for determining caspase-3 and caspase-8 activities in liver tissue homogenates and caspase 3 activity in aortic vascular smooth muscle cells and neuroblastoma cell lines.

Biochem/physiol Actions

Colorimetric substrate for caspase 3, a protease that is rapidly activated when cells are exposed to apoptotic conditions and that cleaves poly(ADP-ribose) polymerase.

AC-DEVD-PNA Preparation Products And Raw materials

Raw materials

Preparation Products

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AC-DEVD-PNA Suppliers

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189950-66-1, AC-DEVD-PNARelated Search:

2-AMINO-9H-PYRIDO[2,3-B]INDOLE ACA N-acetyl aspartyl-glutaMic acid ALA-ALA-VAL-ALA P-NITRO-ANILIDE AC-ASP-PNA VAL-ALA P-NITROANILIDE ACETATE SALT H-VAL-ALA-PNA 4-(4-AMINOANILINO)-4-OXOBUTANOIC ACID AC-DEVD-PNA AC-DEVD-CHO SUC-ALA-ALA-ALA-PNA

  • CASPASE 3 (APOPAIN) SUBSTRATE 1, CHROMOGENIC
  • CASPASE-3 SUBSTRATE VIII, WATER-SOLUBLE, COLORIMETRIC
  • CASPASE 3/CPP32 CHROMOGENIC SUBSTRATE
  • CASPASE-3 SUBSTRATE (CHROMOGENIC)
  • CASPASE-3 SUBSTRATE I, COLORIMETRIC
  • CHROMOGENIC CASPASE 3 SUBSTRATE AC-DEVD-PNA
  • AC-ASP-GLU-VAL-ASP-PARANITROANILIDE
  • AC-ASP-GLU-VAL-ASP-PNA
  • AC-DEVD-PNA
  • ACETYL-DEVD-PNA
  • ACETYL-ASP-GLU-VAL-ASP-(P-NITROANILIDE)
  • N-ACETYL-ASP-GLU-VAL-ASP-P-NITROANILIDE
  • N-ACETYL-ASP-GLU-VAL-ASP-P-NITROANILIDE PNA
  • AC-ASP-GLU-VAL-ASP-P-NITROANILIDE
  • AC-ASP-GLU-VAL-ASP-PNA: AC-DEVD-PNA
  • Ac-DEVD-pNA(Caspase-3 Substrate)
  • Ac-DEVD-pNA,N-Acetyl-Asp-Glu-Val-Asp-p-Nitroanilide, >98%
  • AC-DEVD-PNA?, >98%
  • (2S,5S,8S,11S)
  • -11-(carboxymethyl)
  • -2-(2-Amino-2-oxoethyl)
  • -4,7,10,13-tetraoxo-3,6,9,12-tetraazatetradecan-1-oic acid
  • -5-isopropyl-3-(4-nitrophenyl)
  • -8-(2-carboxyethyl)
  • N-Acetyl-L-α-aspartyl-L-α-glutamyl-L-valyl-N-(4-nitrophenyl)-L-asparagine
  • Ac-DEVD-pNA，Ac-Asp-Glu-Val-Asp-pNA，Ac-Asp-Glu-Val-Asp-p-nitroanilide
  • L-Asparagine, N-acetyl-L-α-aspartyl-L-α-glutamyl-L-valyl-N-(4-nitrophenyl)- (9CI)
  • AC-DEVD-P
  • N-Acetyl-L-a-aspartyl-L-a-glutamyl-L-valyl-N-(4-nitrophenyl)-L-asparagine
  • Ac-DEVD-pNA，N-Acetyl-Asp-Glu-Val-Asp-p-Nitroanilide
  • N-Ac-Asp-Glu-Val-Asp-pNA
  • L-Asparagine,N-acetyl-L-a-aspartyl-L-a-glutamyl-L-valyl-N-(4-nitrophenyl)-(9CI)
  • Ac-DEVD-pNA, 10 mM in DMSO
  • 189950-66-1
  • C26H34N6O13
  • Substrates
  • BioChemical
  • Caspase 3
  • Caspases
  • Cell Biology
  • Cell Signaling and Neuroscience
  • Apoptosis and Cell Cycle
  • Caspase/Related Products
  • Pepetides
  • peptide