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Pristinamycin IA

Product Name
Pristinamycin IA
CAS No.
3131-03-1
Chemical Name
Pristinamycin IA
Synonyms
PA 114B;NSC 92554;mikamycin B;MikaMycin IA;Ostreogrycin B;VirginiaMycin B;Streptogramin B;Pristinamycin IA;Pristinamycin ⅠA;PristinaMycin P 1
CBNumber
CB62079233
Molecular Formula
C45H54N8O10
Formula Weight
866.96
MOL File
3131-03-1.mol
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Pristinamycin IA Property

Melting point:
198°
alpha 
D22 -57.5° (c = 0.25 in ethanol)
Boiling point:
780.3°C (rough estimate)
Density 
1.1881 (rough estimate)
refractive index 
1.6910 (estimate)
storage temp. 
-20°C Freezer
solubility 
DMSO (Slightly), Methanol (Slightly)
form 
Solid
pka
pKa 7.20±0.05(H2O,t =25,I=0.2(LiClO4)) (Uncertain)
color 
Pale Yellow
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Safety

RIDADR 
3172
HazardClass 
6.1(b)
PackingGroup 
III
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Cayman Chemical
Product number
28086
Product name
Streptogramin B
Packaging
1mg
Price
$73
Updated
2024/03/01
Cayman Chemical
Product number
28086
Product name
Streptogramin B
Packaging
25mg
Price
$1075
Updated
2024/03/01
Cayman Chemical
Product number
28086
Product name
Streptogramin B
Packaging
5mg
Price
$253
Updated
2024/03/01
Cayman Chemical
Product number
28086
Product name
Streptogramin B
Packaging
10mg
Price
$468
Updated
2024/03/01
Usbiological
Product number
V2122-82A
Product name
Virginiamycin B
Packaging
5mg
Price
$513
Updated
2021/12/16
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Pristinamycin IA Chemical Properties,Usage,Production

Uses

Virginiamycin B is a depsipeptide antibiotic co-produced with ostreogrycin A, together used as a syngergistic mixture. Virginiamycin B, also known as ostreogrycin B and streptogramin B among other synonyms, was discovered independently and named by several groups, leading to considerable confusion in the literature. Viriginiamycin B acts a syngergist, binding to the conformational change of the peptidyl transferase centre of the 50S ribosome induced by ostreogrycin A.

Uses

One of the two major components of Pristinamycin (Pristinamycin IA and Pristinamycin IIA (or Virginiamycin M1-V673810).

Definition

ChEBI: A cyclodepsipeptide that is (together with pristinamycin IIA) a component of pristinamycin, an oral streptogramin antibiotic produced by Streptomyces pristinaespiralis. Pristinamycin exhibits bactericidal activity against Gram positive organis s including methicillin-resistant Staphylococcus aureus.

Contact allergens

Pristinamycin is a systemic antibiotic of the synergistins/ streptogramins class, composed of two subunits: pristinamycin IA and pristinamycin IIA. It induces several types of drug reactions such as maculo-papular exanthema, systemic dermatitis, or acute generalized exanthematous pustulosis. Some patients have been previously skin-sensitized by virginiamycin. Crossreactivity is expected to virginiamycin and to the associated dalfopristin and quinupristin.

Pristinamycin IA Preparation Products And Raw materials

Raw materials

Preparation Products

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Pristinamycin IA Suppliers

Chemsky (shanghai) International Co.,Ltd
Tel
021-50135380
Email
shchemsky@sina.com
Country
China
ProdList
15402
Advantage
60
Beijing HuaMeiHuLiBiological Chemical
Tel
010-56205725
Fax
010-65763397
Email
waley188@sohu.com
Country
China
ProdList
12335
Advantage
58
MedChemexpress LLC
Tel
021-58955995
Fax
609-228-5909
Email
sales@medchemexpress.cn
Country
United States
ProdList
4861
Advantage
58
ChemStrong Scientific Co.,Ltd
Tel
0755-0755-66853366 13670046396
Fax
0755-28363542
Email
sales@chem-strong.com
Country
China
ProdList
18070
Advantage
56
ShangHai Biochempartner Co.,Ltd
Tel
177-54423994 17754423994
Fax
QQ:2853530913
Email
2853530910@QQ.com
Country
China
ProdList
8012
Advantage
62
Shanghai Rechem science Co., Ltd.
Tel
21-31433387 15618786686
Fax
QQ:1369748377
Email
sales@rechemscience.com
Country
China
ProdList
2988
Advantage
58
Beijing Jin Ming Biotechnology Co., Ltd.
Tel
010-60605840 18892239720
Fax
010-60605840
Email
psaitong@jm-bio.com
Country
China
ProdList
12306
Advantage
58
Lynnchem
Tel
86-(0)29-85992781 17792393971
Email
info@lynnchem.com
Country
China
ProdList
4587
Advantage
58
Novachemistry
Tel
44-20819178-90 02081917890
Fax
(0)2080432064
Email
info@novachemistry.com
Country
United Kingdom
ProdList
4381
Advantage
58
Musechem
Tel
+1-800-259-7612
Fax
+1-800-259-7612
Email
info@musechem.com
Country
United States
ProdList
4660
Advantage
60
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View Lastest Price from Pristinamycin IA manufacturers

Shaanxi Dideu Medichem Co. Ltd
Product
Pristinamycin IA 3131-03-1
Price
US $1.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
20T
Release date
2024-07-07

3131-03-1, Pristinamycin IARelated Search:


  • N-[(3-Hydroxy-2-pyridinyl)carbonyl]-L-threonyl-(2R)-2-aMinobutanoyl-L-prolyl-4-(diMethylaMino)-N-Methyl-L-phenylalanyl-(2S)-4-oxo-2-piperidinecarbonyl-(2S)-2-phenylglycine (6-13)-lactone
  • NSC 92554
  • PA 114B
  • PristinaMycin P 1
  • Ostreogrycin B, PristinaMycin IA, StreptograMin B, Syncothrecin B1, Synergistin B, VernaMycin Balpha, VirginiaMycin 1A, NSC 125176, 14725-1, PA 114B, RP 12535
  • VirginiaMycin B
  • Pristinamycin IA, >95%
  • mikamycin B
  • N-[(3-Hydroxy-2-pyridinyl)carbonyl]cyclo(L-Thr*-D-Abu-L-Pro-N-methyl-4-(dimethylamino)-L-Phe-4-oxo-L-2-piperidinecarbonyl-L-phenyl Gly-)
  • Ostreogrycin B
  • Pristinamycin IA
  • Streptogramin B
  • PristinaMycin IA DISCONTINUED
  • 4-[4-(DiMethylaMino)-N-Methyl-L-phenylalanine]virginiaMycin S1
  • Antibiotic PA 114B
  • Antibiotic PA 114B1
  • MikaMycin IA
  • Virginiamycin S1, 4-[4-(dimethylamino)-N-methyl-L-phenylalanine]-
  • Antibiotic,ribosome,Bacterial,macrolactone,vinblastine,inhibit,Pristinamycin IA,Inhibitor,P-glycoprotein
  • Pristinamycin ⅠA
  • 3131-03-1
  • 131-03-1
  • C45H54N8O10
  • Chiral Reagents
  • Heterocycles
  • Intermediates & Fine Chemicals
  • Pharmaceuticals