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(1R,2R)-trans-N-Boc-2-Aminocyclohexanol

Product Name
(1R,2R)-trans-N-Boc-2-Aminocyclohexanol
CAS No.
155975-19-2
Chemical Name
(1R,2R)-trans-N-Boc-2-Aminocyclohexanol
Synonyms
172618;(1R,2R)-N-Boc-2-aminocyclohexanol;(1R,2R)-2-(Boc-amino)-cyclohexanol;(1R,2R)-trans-N-Boc-2-Aminocyclohexanol;(1R,2R)-N-Boc-2-aminocyclohexanol,99%e.e.;1H-Inden-2-ol,1-amino-2,3-dihydro-,(1R,5S)-;tert-butyl N-[(1R,2R)-2-hydroxycyclohexyl]carbamate;(1R,2R)-trans-2-(N-tert-butyloxycarbonyl)amino-1-cyclohexanol;(1R,2R)-trans-N-Boc-2-aminocyclohexanol;Carbamic acid, N-[(1R,2R)-2-hydroxycyclohexyl]-, 1,1-dimethylethyl ester
CBNumber
CB62091187
Molecular Formula
C11H21NO3
Formula Weight
215.29
MOL File
155975-19-2.mol
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(1R,2R)-trans-N-Boc-2-Aminocyclohexanol Property

Melting point:
110 °C
Boiling point:
337.7±31.0 °C(Predicted)
Density 
1.06±0.1 g/cm3(Predicted)
storage temp. 
2-8°C
pka
12.11±0.40(Predicted)
Appearance
White to off-white Solid
optical activity
[α]/D +4.9±0.5°, c = 1 in chloroform
BRN 
6921870
InChI
1S/C11H21NO3/c1-11(2,3)15-10(14)12-8-6-4-5-7-9(8)13/h8-9,13H,4-7H2,1-3H3,(H,12,14)/t8-,9-/m1/s1
InChIKey
XVROWZPERFUOCE-RKDXNWHRSA-N
SMILES
CC(C)(C)OC(=O)N[C@@H]1CCCC[C@H]1O
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Safety

Hazard Codes 
Xn,N
Risk Statements 
22-50
Safety Statements 
61
RIDADR 
UN 3077 9/PG 3
WGK Germany 
3
HS Code 
2924297099
Storage Class
11 - Combustible Solids
Hazard Classifications
Acute Tox. 4 Oral
Aquatic Acute 1
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H400Very toxic to aquatic life

Precautionary statements

P273Avoid release to the environment.

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N-Bromosuccinimide Price

ChemScene
Product number
CS-0058568
Product name
tert-Butyl((1R,2R)-2-hydroxycyclohexyl)carbamate
Packaging
5g
Price
$113
Updated
2021/12/16
AK Scientific
Product number
4702AJ
Product name
(1R,2R)-trans-N-Boc-2-aminocyclohexanol
Packaging
5g
Price
$211
Updated
2021/12/16
ChemScene
Product number
CS-0058568
Product name
tert-Butyl((1R,2R)-2-hydroxycyclohexyl)carbamate
Packaging
10g
Price
$220
Updated
2021/12/16
ChemScene
Product number
CS-0058568
Product name
tert-Butyl((1R,2R)-2-hydroxycyclohexyl)carbamate
Packaging
25g
Price
$363
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
CCH0000002
Product name
(1R,2R)-TRANS-N-BOC-2-AMINOCYCLOHEXANOL
Purity
95.00%
Packaging
250MG
Price
$690.42
Updated
2021/12/16
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(1R,2R)-trans-N-Boc-2-Aminocyclohexanol Chemical Properties,Usage,Production

Synthesis

364385-55-7

155975-19-2

Step B: Preparation of tert-butyl (1R,2R)-(2-hydroxycyclohexyl)carbamate To a mixed solution of tert-butyl (1R,2R)-(2-benzyloxycyclohexyl)carbamate (7 g, 23 mmol) in ethyl acetate and methanol (80 mL, 9:1) was added 10% Pd-C catalyst (1.13 g). The hydrogenation reaction was carried out at 35 psi hydrogen pressure for 4 hours. Upon completion of the reaction, it was filtered through a diatomaceous earth pad to remove the catalyst. The filtrate was concentrated to give the target product (Cas:155975-19-2) as an oil (4.7 g, 95% yield). Mass spectrometry (MS) analysis: (M + 1): 215.95.

References

[1] Patent: US2007/287695, 2007, A1. Location in patent: Page/Page column 14; 55
[2] Bioorganic and Medicinal Chemistry, 2009, vol. 17, # 1, p. 119 - 132

(1R,2R)-trans-N-Boc-2-Aminocyclohexanol Preparation Products And Raw materials

Raw materials

Preparation Products

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(1R,2R)-trans-N-Boc-2-Aminocyclohexanol Suppliers

Adamas Reagent, Ltd.
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China
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View Lastest Price from (1R,2R)-trans-N-Boc-2-Aminocyclohexanol manufacturers

Henan Fengda Chemical Co., Ltd
Product
(1R,2R)-trans-N-Boc-2-Aminocyclohexanol 155975-19-2
Price
US $34.00-1.20/kg
Min. Order
1kg
Purity
99%
Supply Ability
g-kg-tons, free sample is available
Release date
2024-04-08

155975-19-2, (1R,2R)-trans-N-Boc-2-AminocyclohexanolRelated Search:


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