Indobufen

ChemicalBook > CAS DataBase List > Indobufen

Product Name: Indobufen
CAS No.: 63610-08-2
Chemical Name: Indobufen
Synonyms: 2-(4-(1-oxoisoindolin-2-yl)phenyl)butanoic acid;d-INB;K 2930;K-3920;Ibustrin;INDOBUFEN;INDOBNFEN;lndobufen;d-Indobufen;Indobuprofen
CBNumber: CB6213695
Molecular Formula: C18H17NO3
Formula Weight: 295.34
MOL File: 63610-08-2.mol

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Indobufen Property

Melting point:: 182-184°
Boiling point:: 518.1±50.0 °C(Predicted)
Density: 1.275±0.06 g/cm3(Predicted)
storage temp.: Keep in dark place,Sealed in dry,Room Temperature
solubility: DMSO (Slightly), Methanol (Slightly)
form: Solid
pka: 4.39±0.10(Predicted)
color: White
InChI: InChI=1S/C18H17NO3/c1-2-15(18(21)22)12-7-9-14(10-8-12)19-11-13-5-3-4-6-16(13)17(19)20/h3-10,15H,2,11H2,1H3,(H,21,22)
InChIKey: AYDXAULLCROVIT-UHFFFAOYSA-N
SMILES: O=C1C2C=CC=CC=2CN1C1C=CC(C(CC)C(=O)O)=CC=1
CAS DataBase Reference: 63610-08-2(CAS DataBase Reference)
EPA Substance Registry System: Benzeneacetic acid, 4-(1,3-dihydro-1-oxo-2H-isoindol-2-yl)-.alpha.-ethyl- (63610-08-2)

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

Precautionary statements

P280Wear protective gloves/protective clothing/eye protection/face protection.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

TRC

Product number: I576500
Product name: Indobufen
Packaging: 25mg
Price: $70
Updated: 2021/12/16

ChemScene

Product number: CS-0014291
Product name: Indobufen
Purity: 99.98%
Packaging: 5mg
Price: $60
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: API0004904
Product name: INDOBUFEN
Purity: 95.00%
Packaging: 25MG
Price: $288.75
Updated: 2021/12/16

Medical Isotopes, Inc.

Product number: 46849
Product name: Indobufen
Packaging: 100mg
Price: $640
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: API0004904
Product name: INDOBUFEN
Purity: 95.00%
Packaging: 100MG
Price: $739.2
Updated: 2021/12/16

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Indobufen Chemical Properties,Usage,Production

Description

Indobufen is a platelet aggregation inhibitor related to the antiinflammatory agent indoprofen. It has shown clinical efficacy in peripheral artery disease, in prevention of deep vein thrombosis after myocardial infarction, and in blocking excercise-induced increase in platelet aggregation in angina patients.

Originator

Erbamont (Italy)

Uses

Indobufen is a platelet aggregation inhibitor. Indobufen is the anticoagulant drug and platelet aggregation inhibitor, which has anti-inflammatory analgesic effect. Indobufen is used as an antithrombotic.

Definition

ChEBI: Indobufen is a member of isoindoles.

brand name

IBUSTRIN

Clinical Use

A reversible but very potent inhibitor of platelet COX-1 activity, was shown to have comparable clinical efficacy to that of aspirin in prevention of DVT after myocardial infarction and in blocking exercise-induced increase in platelet aggregation. In the secondary prevention of thromboembolic events, 100 or 200 mg of indobufen twice daily is as effective as warfarin or aspirin in patients with or without atrial fibrillation. Currently, indobufen is only available for routine clinical use in Europe.

Indobufen Preparation Products And Raw materials

Raw materials

Isoindoline Potassium carbonate Benzyl bromide Phthalic anhydride α-(p-Aminophenyl)butyric acid

Preparation Products

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View Lastest Price from Indobufen manufacturers

WUHAN FORTUNA CHEMICAL CO., LTD

Product: Indobufen 63610-08-2
Price: US $0.00-0.00/Kg/Drum
Min. Order: 1KG
Purity: 99%minHPLC
Supply Ability: 1000KG
Release date: 2021-06-18

Hebei Dangtong Import and export Co LTD

Product: Indobufen 63610-08-2
Price: US $95.00-85.00/kilograms
Min. Order: 1kilograms
Purity: 99%
Supply Ability: 100tons
Release date: 2023-02-14

airuikechemical co., ltd.

Product: Indobufen 63610-08-2
Price: US $0.00-0.00/g
Min. Order: 1g
Purity: 99.9%
Supply Ability: 20tons
Release date: 2024-04-07

63610-08-2, IndobufenRelated Search:

Indole-3-butyric acid Indole Hyaluronic acid Ethylbenzene Citric acid Ethyl 2-(Chlorosulfonyl)acetate Dihydromyrcenol Indole-3-acetic acid Folic acid Indometacin α-(p-Aminophenyl)butyric acid Indoline-2-carboxylic acid INDOMETHACIN SODIUM SALT TRIHYDRATE Indole-3-carbinol 7-Hydroxygranisetron INDOXYL ACETATE Indoline Indole-3-carboxaldehyde

1-Oxo-2-[p-[(α-ethyl)carboxyMethyl]phenyl]isoindoline

2-[p-(1-Oxo-2-isoindolinyl)phenyl]butyric Acid

K 2930

(+-)-butyricaci

1-oxo-2-(p-((alpha-ethyl)carboxymethyl)phenyl)isoindoline

4-(1,3-dihydro-1-oxo-2h-isoindol-2-yl)-alpha-ethyl-benzeneaceticacid

2-[4-(1-OXO-1,3-DIHYDRO-ISOINDOL-2-YL)-PHENYL]-BUTYRIC ACID

lndobufen

INDOBNFEN

INDOBUFEN

2-[4-(1-oxo-2-isoindolinyl)phenyl]butyric acid

(2R)-2-[4-(3-Oxo-1H-isoindol-2-yl)phenyl]butanoic acid

1-Oxo-2-(p-((a-ethyl)carboxymethyl)phenyl)isoindoline

4-(1,3-Dihydro-1-oxo-2H-isoindol-2-yl)a-ethyl-benzeneacetic acid

Benzeneacetic acid, 4-(1,3-dihydro-1-oxo-2H-isoindol-2-yl)-a-ethyl-

Butyric acid, 2-(p-(1-oxo-2-isoindolinyl)phenyl)-, (+-)

(±)-4-(1,3-Dihydro-1-oxo-2H-isoindol-2-yl)-α-ethylbenzeneacetic acid

(αR)-4-[(1,3-Dihydro-1-oxo-2H-isoindole)-2-yl]-α-ethylbenzeneacetic acid

[R,(-)]-4-[(1,3-Dihydro-1-oxo-2H-isoindole)-2-yl]-α-ethylbenzeneacetic acid

(αS)-4-[(1,3-Dihydro-1-oxo-2H-isoindol)-2-yl]-α-ethylbenzeneacetic acid

d-INB

d-Indobufen

Benzeneacetic acid, 4-(1,3-dihydro-1-oxo-2H-isoindol-2-yl)-alpha-ethyl-

Ibustrin

K-3920

Ibustrin， K 3920

Benzeneacetic acid, 4-(1,3-dihydro-1-oxo-2H-isoindol-2-yl)-α-ethyl-

2-(4-(1-oxoisoindolin-2-yl)phenyl)butanoic acid

Indobufen USP/EP/BP

(2S)-2-[4-(3-oxo-1H-isoindol-2-yl)phenyl]butanoic acid

63610-08-2,Indobufen

Indole cloth Finn

Indobufen WRS

2-[4-(3-oxo-1H-isoindol-2-yl)phenyl]butanoicaci

Indobuprofen

63610-08-2

Amines

Aromatics

Heterocycles

Intermediates & Fine Chemicals

Pharmaceuticals

63610-08-2

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