ChemicalBook > CAS DataBase List > Indobufen

Indobufen

Product Name
Indobufen
CAS No.
63610-08-2
Chemical Name
Indobufen
Synonyms
2-(4-(1-oxoisoindolin-2-yl)phenyl)butanoic acid;d-INB;K 2930;K-3920;Ibustrin;INDOBUFEN;INDOBNFEN;lndobufen;d-Indobufen;Indobuprofen
CBNumber
CB6213695
Molecular Formula
C18H17NO3
Formula Weight
295.34
MOL File
63610-08-2.mol
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Indobufen Property

Melting point:
182-184°
Boiling point:
518.1±50.0 °C(Predicted)
Density 
1.275±0.06 g/cm3(Predicted)
storage temp. 
Keep in dark place,Sealed in dry,Room Temperature
solubility 
DMSO (Slightly), Methanol (Slightly)
form 
Solid
pka
4.39±0.10(Predicted)
color 
White
InChI
InChI=1S/C18H17NO3/c1-2-15(18(21)22)12-7-9-14(10-8-12)19-11-13-5-3-4-6-16(13)17(19)20/h3-10,15H,2,11H2,1H3,(H,21,22)
InChIKey
AYDXAULLCROVIT-UHFFFAOYSA-N
SMILES
O=C1C2C=CC=CC=2CN1C1C=CC(C(CC)C(=O)O)=CC=1
CAS DataBase Reference
63610-08-2(CAS DataBase Reference)
EPA Substance Registry System
Benzeneacetic acid, 4-(1,3-dihydro-1-oxo-2H-isoindol-2-yl)-.alpha.-ethyl- (63610-08-2)
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

Precautionary statements

P280Wear protective gloves/protective clothing/eye protection/face protection.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

TRC
Product number
I576500
Product name
Indobufen
Packaging
25mg
Price
$70
Updated
2021/12/16
ChemScene
Product number
CS-0014291
Product name
Indobufen
Purity
99.98%
Packaging
5mg
Price
$60
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
API0004904
Product name
INDOBUFEN
Purity
95.00%
Packaging
25MG
Price
$288.75
Updated
2021/12/16
Medical Isotopes, Inc.
Product number
46849
Product name
Indobufen
Packaging
100mg
Price
$640
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
API0004904
Product name
INDOBUFEN
Purity
95.00%
Packaging
100MG
Price
$739.2
Updated
2021/12/16
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Indobufen Chemical Properties,Usage,Production

Description

Indobufen is a platelet aggregation inhibitor related to the antiinflammatory agent indoprofen. It has shown clinical efficacy in peripheral artery disease, in prevention of deep vein thrombosis after myocardial infarction, and in blocking excercise-induced increase in platelet aggregation in angina patients.

Originator

Erbamont (Italy)

Uses

Indobufen is a platelet aggregation inhibitor. Indobufen is the anticoagulant drug and platelet aggregation inhibitor, which has anti-inflammatory analgesic effect. Indobufen is used as an antithrombotic.

Definition

ChEBI: Indobufen is a member of isoindoles.

brand name

IBUSTRIN

Clinical Use

A reversible but very potent inhibitor of platelet COX-1 activity, was shown to have comparable clinical efficacy to that of aspirin in prevention of DVT after myocardial infarction and in blocking exercise-induced increase in platelet aggregation. In the secondary prevention of thromboembolic events, 100 or 200 mg of indobufen twice daily is as effective as warfarin or aspirin in patients with or without atrial fibrillation. Currently, indobufen is only available for routine clinical use in Europe.

Indobufen Preparation Products And Raw materials

Raw materials

Isoindoline Potassium carbonate Benzyl bromide Phthalic anhydride α-(p-Aminophenyl)butyric acid

Preparation Products

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View Lastest Price from Indobufen manufacturers

WUHAN FORTUNA CHEMICAL CO., LTD
Product
Indobufen 63610-08-2
Price
US $0.00-0.00/Kg/Drum
Min. Order
1KG
Purity
99%minHPLC
Supply Ability
1000KG
Release date
2021-06-18
Wuhan Senwayer Century Chemical Co.,Ltd
Product
Indobufen 63610-08-2
Price
US $0.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
20 TONS
Release date
2022-11-07
Hebei Dangtong Import and export Co LTD
Product
Indobufen 63610-08-2
Price
US $95.00-85.00/kilograms
Min. Order
1kilograms
Purity
99%
Supply Ability
100tons
Release date
2023-02-14

63610-08-2, IndobufenRelated Search:

Indole-3-butyric acid Indole Hyaluronic acid Ethylbenzene Citric acid Ethyl 2-(Chlorosulfonyl)acetate Dihydromyrcenol Indole-3-acetic acid Folic acid Indometacin α-(p-Aminophenyl)butyric acid Indoline-2-carboxylic acid INDOMETHACIN SODIUM SALT TRIHYDRATE Indole-3-carbinol 7-Hydroxygranisetron INDOXYL ACETATE Indoline Indole-3-carboxaldehyde

  • 1-Oxo-2-[p-[(α-ethyl)carboxyMethyl]phenyl]isoindoline
  • 2-[p-(1-Oxo-2-isoindolinyl)phenyl]butyric Acid
  • K 2930
  • (+-)-butyricaci
  • 1-oxo-2-(p-((alpha-ethyl)carboxymethyl)phenyl)isoindoline
  • 4-(1,3-dihydro-1-oxo-2h-isoindol-2-yl)-alpha-ethyl-benzeneaceticacid
  • 2-[4-(1-OXO-1,3-DIHYDRO-ISOINDOL-2-YL)-PHENYL]-BUTYRIC ACID
  • lndobufen
  • INDOBNFEN
  • INDOBUFEN
  • 2-[4-(1-oxo-2-isoindolinyl)phenyl]butyric acid
  • (2R)-2-[4-(3-Oxo-1H-isoindol-2-yl)phenyl]butanoic acid
  • 1-Oxo-2-(p-((a-ethyl)carboxymethyl)phenyl)isoindoline
  • 4-(1,3-Dihydro-1-oxo-2H-isoindol-2-yl)a-ethyl-benzeneacetic acid
  • Benzeneacetic acid, 4-(1,3-dihydro-1-oxo-2H-isoindol-2-yl)-a-ethyl-
  • Butyric acid, 2-(p-(1-oxo-2-isoindolinyl)phenyl)-, (+-)
  • (±)-4-(1,3-Dihydro-1-oxo-2H-isoindol-2-yl)-α-ethylbenzeneacetic acid
  • (αR)-4-[(1,3-Dihydro-1-oxo-2H-isoindole)-2-yl]-α-ethylbenzeneacetic acid
  • [R,(-)]-4-[(1,3-Dihydro-1-oxo-2H-isoindole)-2-yl]-α-ethylbenzeneacetic acid
  • (αS)-4-[(1,3-Dihydro-1-oxo-2H-isoindol)-2-yl]-α-ethylbenzeneacetic acid
  • d-INB
  • d-Indobufen
  • Benzeneacetic acid, 4-(1,3-dihydro-1-oxo-2H-isoindol-2-yl)-alpha-ethyl-
  • Ibustrin
  • K-3920
  • Ibustrin， K 3920
  • Benzeneacetic acid, 4-(1,3-dihydro-1-oxo-2H-isoindol-2-yl)-α-ethyl-
  • 2-(4-(1-oxoisoindolin-2-yl)phenyl)butanoic acid
  • Indobufen USP/EP/BP
  • (2S)-2-[4-(3-oxo-1H-isoindol-2-yl)phenyl]butanoic acid
  • 63610-08-2,Indobufen
  • Indole cloth Finn
  • Indobufen WRS
  • 2-[4-(3-oxo-1H-isoindol-2-yl)phenyl]butanoicaci
  • Indobuprofen
  • 63610-08-2
  • Amines
  • Aromatics
  • Heterocycles
  • Intermediates & Fine Chemicals
  • Pharmaceuticals
  • 63610-08-2
  • API