ChemicalBook > CAS DataBase List > N,N'-Bis(phenylmethyl)-1,2-ethanediamine

N,N'-Bis(phenylmethyl)-1,2-ethanediamine

Product Name
N,N'-Bis(phenylmethyl)-1,2-ethanediamine
CAS No.
140-28-3
Chemical Name
N,N'-Bis(phenylmethyl)-1,2-ethanediamine
Synonyms
Dbed;BENZATHINE;N1,N2-Dibenzylethane-1,2-diaMine;Benzatin;Nsc5632;usafdo-53;USAF do-53;N,N'-DibenzyL;BENZATHINE 99%;enediamine Diacetate SaL
CBNumber
CB6214137
Molecular Formula
C16H20N2
Formula Weight
240.34
MOL File
140-28-3.mol
More
Less

N,N'-Bis(phenylmethyl)-1,2-ethanediamine Property

Melting point:
23-25°C
Boiling point:
195 °C4 mm Hg(lit.)
Density 
1.02 g/mL at 25 °C(lit.)
refractive index 
n20/D 1.565(lit.)
Flash point:
>230 °F
storage temp. 
Room Temperature
solubility 
Chloroform (Slightly), Ethyl Acetate (Slightly), Water (Slightly)
form 
Solid
pka
9.15±0.19(Predicted)
Specific Gravity
1.025
color 
White to Off-White
Water Solubility 
Slightly soluble in water.
FreezingPoint 
21.0 to 25.0 ℃
Sensitive 
Air Sensitive
Merck 
14,1064
BRN 
786668
CAS DataBase Reference
140-28-3(CAS DataBase Reference)
NIST Chemistry Reference
1,2-Ethanediamine, N,N'-bis(phenylmethyl)-(140-28-3)
EPA Substance Registry System
1,2-Ethanediamine, N,N'-bis(phenylmethyl)- (140-28-3)
More
Less

Safety

Hazard Codes 
Xn
Risk Statements 
22-36/37/38
Safety Statements 
26
RIDADR 
2927
WGK Germany 
3
RTECS 
KV3325000
TSCA 
Yes
HazardClass 
8
PackingGroup 
III
HS Code 
29215990
Toxicity
LD50 orl-mus: 388 mg/kg CNCRA6 52,579,68
More
Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

More
Less

N-Bromosuccinimide Price

Sigma-Aldrich
Product number
D35201
Product name
N,N′-Dibenzylethylenediamine
Purity
97%
Packaging
25g
Price
$94.9
Updated
2024/03/01
Sigma-Aldrich
Product number
D35201
Product name
N,N′-Dibenzylethylenediamine
Purity
97%
Packaging
100g
Price
$217
Updated
2024/03/01
TCI Chemical
Product number
D1807
Product name
N,N'-Dibenzylethylenediamine
Purity
>98.0%(GC)(T)
Packaging
25mL
Price
$94
Updated
2024/03/01
TCI Chemical
Product number
D1807
Product name
N,N'-Dibenzylethylenediamine
Purity
>98.0%(GC)(T)
Packaging
500mL
Price
$906
Updated
2024/03/01
Alfa Aesar
Product number
L03540
Product name
N,N'-Dibenzylethylenediamine, 97%
Packaging
25g
Price
$73.65
Updated
2024/03/01
More
Less

N,N'-Bis(phenylmethyl)-1,2-ethanediamine Chemical Properties,Usage,Production

Chemical Properties

light yellow liquid

Uses

N,N'-Dibenzylethylenediamine is an intermediate of cephalosporin and penicillin.

Definition

ChEBI: Benzathine is a diamine. It is a conjugate base of a benzathine(1+).

Synthesis Reference(s)

The Journal of Organic Chemistry, 55, p. 3209, 1990 DOI: 10.1021/jo00297a042

Safety Profile

Poison by ingestion,intraperitoneal, and parenteral routes. When heated todecomposition it emits toxic vapors of NOx.

Purification Methods

Dissolve DBED in acid, extract with toluene, basify, extract it with Et2O, dry over solid KOH, evaporate and fractionate it in vacuo. The diacetate crystallises from H2O by addition of EtOH and has m 111o (solubility in H2O is ~25%). The dihydrochloride has m 306-308o (from H2O) and the dipicrate has m 212o(dec) (from H2O). [Frost et al., J Am Chem Soc 71 3842 1949, Beilstein 12 H 1067, 12 III 2304.]

N,N'-Bis(phenylmethyl)-1,2-ethanediamine Preparation Products And Raw materials

Raw materials

Preparation Products

More
Less

N,N'-Bis(phenylmethyl)-1,2-ethanediamine Suppliers

Chongqing Xingcan Pharmaceutical Technology Co., Ltd.
Tel
15523000485
Email
xingcanyaoye@sina.com
Country
China
ProdList
1686
Advantage
58
J & K SCIENTIFIC LTD.
Tel
010-82848833 400-666-7788
Fax
86-10-82849933
Email
jkinfo@jkchemical.com
Country
China
ProdList
96815
Advantage
76
Meryer (Shanghai) Chemical Technology Co., Ltd.
Tel
021-61259108 18621169109
Fax
86-21-61259102
Email
market03@meryer.com
Country
China
ProdList
40228
Advantage
62
Alfa Aesar
Tel
400-6106006
Fax
021-67582001/03/05
Email
saleschina@alfa-asia.com
Country
China
ProdList
30123
Advantage
84
Dr. J. Pharmachem (India)
Tel
+91 20 24332987
Fax
+91 20 24332137
Email
info@jpharmachem.com
Country
India
ProdList
97
Advantage
55
TCI (Shanghai) Development Co., Ltd.
Tel
021-67121386
Fax
021-67121385
Email
Sales-CN@TCIchemicals.com
Country
China
ProdList
24529
Advantage
81
Energy Chemical
Tel
021-021-58432009 400-005-6266
Fax
021-58436166
Email
sales8178@energy-chemical.com
Country
China
ProdList
44689
Advantage
61
Beijing Ouhe Technology Co., Ltd
Tel
010-82967028 13552068683
Fax
+86-10-82967029
Email
2355560935@qq.com
Country
China
ProdList
12390
Advantage
60
Jia Xing Isenchem Co.,Ltd
Tel
0573-85285100 18627885956
Fax
0573-85285100
Email
isenchem@163.com
Country
China
ProdList
9413
Advantage
66
Shanghai Hanhong Scientific Co.,Ltd.
Tel
021-54306202 13764082696
Email
info@hanhongsci.com
Country
China
ProdList
42958
Advantage
64
More
Less

View Lastest Price from N,N'-Bis(phenylmethyl)-1,2-ethanediamine manufacturers

Career Henan Chemical Co
Product
N,N'-Bis(phenylmethyl)-1,2-ethanediamine 140-28-3
Price
US $3.00/KG
Min. Order
1KG
Purity
98%
Supply Ability
1kg , 5kg, 50kg
Release date
2020-01-17

140-28-3, N,N'-Bis(phenylmethyl)-1,2-ethanediamineRelated Search:


  • N,N'-DIBENZYLETHYLENEDIAMINE
  • N'N-DIBENZYL-ETHYLENEDIAMINE
  • 1,2-di(benzylamino)ethane
  • Benzathine~1,2-Bis(benzylamino)ethane
  • N,N`-dibenzylethylendiamine
  • BENZATHINE 99%
  • 1 2-BIS(BENZYLAMINO)ETHANE 99%
  • 1,2-ETHANEDIAMINE,N,N''-BIS(PHENYLMETHYL)-
  • N,N'-Bis(phenylmethyl)ethane-1,2-diamine
  • Nsc5632
  • N1,N2-Dibenzylethane-1,2-diaMine
  • N,N'-DibenzylethylenediaMine Diacetate Salt
  • <i>N</i>,<i>N</i>'-Dibenzylethylenediamine
  • Benzatin
  • Dbed
  • n,n’-bis(phenylmethyl)-2-ethanediamine
  • n,n’-dibenzyl-ethylenediamin
  • N,N'-Dibenzyl-1,2-ethanediamine
  • N,N'-Dibenzyl-1,2-ethylenediamine
  • N,N'-Dibenzyl-ethane-1,2-diamine
  • USAF do-53
  • usafdo-53
  • 1 2-BIS(BENZYLAMINO)ETHANE
  • ETHYLENEDIAMINE-N N'-DIBENZYL
  • BENZATHINE
  • N,N'-BIS(PHENYLMETHYL)-1,2-ETHANEDIAMINE
  • DBE, N,N'-Dibenzylethylenediamine
  • N,N'-Dibenzylethylenediamine&gt
  • enediamine Diacetate SaL
  • N,N'-DibenzyL
  • ETHYLENEDIAMINE-N,N'-DIBENZYL 140-28-3
  • N,N'-Bis(phenylmethyl)-1,2-ethanediamine ISO 9001:2015 REACH
  • N,N'-Dibenzylethylenediamine
  • N,N'-Bis(phenylmethyl)-1,2-ethanediamine
  • N,N'-dibenzylethane-1,2-diamine
  • Enzastaurin Impurity 2 (Bisindolylmaleimide IV)
  • 140-28-3
  • C6H5CH2NHCH2CH2NHCH2C6H5
  • C6H5CH2NHCH2CH2NHCH2C6H52CH3CO2H
  • Organic Building Blocks
  • Nitrogen Compounds
  • Polyamines
  • Building Blocks
  • Nitrogen Compounds
  • Organic Building Blocks
  • Polyamines