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DAGO ACETATE SALT

Product Name
DAGO ACETATE SALT
CAS No.
100929-53-1
Chemical Name
DAGO ACETATE SALT
Synonyms
DAMGO, DAGO;DAMGO acetate;DAGO ACETATE SALT;DAMGO ACETATE SALT;ala(2)-mephe(4)-gly(5)-enkephali;Enkephalin, Ala(2)-MePhe(4)-Gly(5)-;(D-ala2,N-me-phe4,gly5-ol)-enkephalin*acetate;TYR-D-ALA-GLY-N-METHYL-PHE-GLY-OL ACETATE SALT;DAGO, DAMGO, Tyr-D-Ala-Gly-N-methyl-Phe-Gly-ol;[D-ALA2,N-ME-PHE4,GLY5-OL]-ENKEPHALIN ACETATE SALT
CBNumber
CB6215598
Molecular Formula
C28H39N5O8
Formula Weight
573.64
MOL File
100929-53-1.mol
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DAGO ACETATE SALT Property

storage temp. 
−20°C
form 
Powder
EPA Substance Registry System
L-Tyrosyl-D-alanylglycyl-N-(2-hydroxyethyl)-N-.alpha.-methyl-L-phenylalaninamide monoacetate (salt) (100929-53-1)
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Safety

WGK Germany 
3
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
E7384
Product name
[D-Ala2, N-Me-Phe4, Gly5-ol]-Enkephalin acetate salt
Purity
≥97% (HPLC)
Packaging
1mg
Price
$62.9
Updated
2024/03/01
Sigma-Aldrich
Product number
E7384
Product name
[D-Ala2, N-Me-Phe4, Gly5-ol]-Enkephalin acetate salt
Purity
≥97% (HPLC)
Packaging
5mg
Price
$204
Updated
2024/03/01
Alfa Aesar
Product number
J60431
Product name
DAGO
Packaging
5mg
Price
$122
Updated
2021/12/16
Sigma-Aldrich
Product number
E7384
Product name
[D-Ala2, N-Me-Phe4, Gly5-ol]-Enkephalin acetate salt
Purity
≥97% (HPLC)
Packaging
10mg
Price
$349
Updated
2024/03/01
Sigma-Aldrich
Product number
E7384
Product name
[D-Ala2, N-Me-Phe4, Gly5-ol]-Enkephalin acetate salt
Purity
≥97% (HPLC)
Packaging
50mg
Price
$1400
Updated
2024/03/01
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DAGO ACETATE SALT Chemical Properties,Usage,Production

Uses

Mu-opioid receptor-specific enkephalin analog

Uses

[D-Ala2, N-Me-Phe4, Gly5-ol]-Enkephalin acetate salt or DAMGO has been used:

  • for use as a positive control in the assay of G-protein activation with μ-opioid receptor, to assay the inhibition of cAMP inhibition by DAMGO
  • for the determination of the suppression of contraction by opioid receptors
  • to determine whether the peripheral application of DAMGO suppresses the hypertonic saline (HS)-induced masseter nociception in slightly anaesthetized rats

General Description

[D-Ala2, N-Me-Phe4, Gly5-ol]-Enkephalin acetate salt or DAMGO is a full agonist of the μ-opioid receptor. μ-opioid receptor is encoded by the OPRM1 gene, which has a predominant expression in reward-processing areas of brain. It acts as a receptor for endogenous opioids such as β-endorphin, encephalin, as well as foreign opioids such as morphine, heroin, and methadone.

Biochem/physiol Actions

Enkephalin analog that is a selective agonist at μ-opioid receptors.

DAGO ACETATE SALT Preparation Products And Raw materials

Raw materials

Preparation Products

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DAGO ACETATE SALT Suppliers

Carbosynth
Tel
--
Fax
--
Email
sales@carbosynth.com
Country
United Kingdom
ProdList
6005
Advantage
58

100929-53-1, DAGO ACETATE SALTRelated Search:


  • ala(2)-mephe(4)-gly(5)-enkephali
  • DAMGO ACETATE SALT
  • DAGO ACETATE SALT
  • [D-ALA2,N-ME-PHE4,GLY5-OL]-ENKEPHALIN ACETATE SALT
  • Enkephalin, Ala(2)-MePhe(4)-Gly(5)-
  • (D-alanine2,N-methylphenylalanine4,glycine3-ol)enkephalin
  • DAGO, DAMGO, Tyr-D-Ala-Gly-N-methyl-Phe-Gly-ol
  • L-Phenylalaninamide, L-tyrosyl-D-alanylglycyl-N-(2-hydroxyethyl)-nalpha-methyl-, monoacetate (salt)
  • L-Tyrosyl-D-alanylglycyl-N-(2-hydroxyethyl)-N-alpha-methyl-L-phenylalaninamide monoacetate (salt)
  • TYR-D-ALA-GLY-N-METHYL-PHE-GLY-OL ACETATE SALT
  • (D-ala2,N-me-phe4,gly5-ol)-enkephalin*acetate
  • L-Tyrosyl-D-alanylglycyl-N-(2-hydroxyethyl)-nalpha-methyl-L-phenylalaninamide monoacetate (salt)
  • DAMGO, DAGO
  • DAMGO acetate
  • (D-Ala?,N-Me-Phe?,glycinol?)-Enkephalin acetate salt
  • (2S)-2-amino-N-[(1R)-1-[[[(1S)-1-(2-hydroxyethylcarbamoyl)-2-phenyl-ethyl]-methyl-carbamoyl]methylcarbamoyl]ethyl]-3-(4-hydroxyphenyl)propanamide
  • 100929-53-1
  • C28H39N5O8
  • C26H35N5O6C2H4O2
  • Biochemicals and Reagents
  • Amino Acids and Peptides
  • BioChemical
  • Peptides
  • Opioid Peptides
  • Enkephalins