ChemicalBook > CAS DataBase List > 2-MONOPALMITIN

2-MONOPALMITIN

Product Name: 2-MONOPALMITIN
CAS No.: 23470-00-0
Chemical Name: 2-MONOPALMITIN
Synonyms: 2-MONOOLEIN;2-Monopalmitoylglycerol;2-Palmitoyl-rac-glycerol;2-O-Palmitoylglycerol;2-Hexadecanoylglycerol;2-O-Palmitoyl-L-glycerol;Glyceryl 2-monopalmitate;2-O-Hexadecanoylglycerol;2-Monohexadecanoylglycerol;2-monopalmitoylglycerol (C16:0)
CBNumber: CB6222338
Molecular Formula: C19H38O4
Formula Weight: 330.5
MOL File: 23470-00-0.mol

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2-MONOPALMITIN Property

Melting point:: 68-70°C
Boiling point:: 387.92°C (rough estimate)
Density: 0.9708 (rough estimate)
refractive index: 1.4434 (estimate)
storage temp.: −20°C
solubility: Chloroform (Slightly), Ethyl Acetate (Slightly), Methanol (Slightly)
pka: 13.54±0.10(Predicted)
form: Solid
color: White to Off-White
biological source: synthetic
BRN: 1796692

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Safety

Hazard Codes: Xi
Risk Statements: 43
Safety Statements: 36/37
WGK Germany: 3

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 75614
Product name: 2-Palmitoylglycerol
Purity: analytical standard
Packaging: 25mg
Price: $460
Updated: 2025/07/31

Cayman Chemical

Product number: 17882
Product name: 2-Palmitoyl Glycerol
Purity: ≥95%
Packaging: 5mg
Price: $44
Updated: 2024/03/01

Cayman Chemical

Product number: 17882
Product name: 2-Palmitoyl Glycerol
Purity: ≥95%
Packaging: 10mg
Price: $70
Updated: 2024/03/01

Cayman Chemical

Product number: 17882
Product name: 2-Palmitoyl Glycerol
Purity: ≥95%
Packaging: 25mg
Price: $161
Updated: 2024/03/01

Cayman Chemical

Product number: 17882
Product name: 2-Palmitoyl Glycerol
Purity: ≥95%
Packaging: 50mg
Price: $299
Updated: 2024/03/01

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2-MONOPALMITIN Chemical Properties,Usage,Production

Description

2-Arachidonoyl glycerol (2-AG; ) is an endogenous agonist of the CB₁ and CB₂ cannabinoid receptors. 2-Palmitoyl glycerol is a fatty acid ester that does not bind directly to cannabinoid receptors, nor inhibit adenylyl cyclase, but rather potentiates the activity of 2-AG (and other endocannabinoids) to bind to CB₁ and CB₂ and inhibit adenylyl cyclase. This “entourage” effect has been attributed to blockade of the breakdown and reuptake pathways that normally function to reduce endocannabinoid levels rapidly upon release. 2-Palmitoyl glycerol and related endogenous fatty acid derivatives have been shown to interact with endocannabinoids in the modulation of pain sensitivity.

Chemical Properties

White Solid

Uses

A biomarker of metabolic responses to hepatotoxicants and carcinogens.

Definition

ChEBI: A 2-monoglyceride where the acyl group is hexadecanoyl (palmitoyl).

Biological Activity

Endogenous fatty acid glycerol ester that enhances activity of 2-arachidonylglycerol ((5Z,8Z,11Z,14Z)-5,8,11,14-Eicosatetraenoic acid,2-hydroxy-1-(hydroxymethyl)ethyl ester ). Does not bind to CB 1 or CB 2 cannabinoid receptors, but potentiates the apparent binding of 2-AG and increases its ability to inhibit adenylyl cyclase. Enhances in vivo cannabinoid effects of 2-AG following combined administration with 2-linoleoylglycerol.

References

[1] SHIMON BEN-SHABAT . An entourage effect: inactive endogenous fatty acid glycerol esters enhance 2-arachidonoyl-glycerol cannabinoid activity[J]. European journal of pharmacology, 1998, 353 1: Pages 23-31. DOI: 10.1016/s0014-2999(98)00392-6
[2] J.MICHAEL WALKER. Endocannabinoids and related fatty acid derivatives in pain modulation[J]. Chemistry and Physics of Lipids, 2002, 121 1: Pages 159-172. DOI: 10.1016/s0009-3084(02)00152-4

2-MONOPALMITIN Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from 2-MONOPALMITIN manufacturers

Career Henan Chemical Co

Product: 2-MONOPALMITIN 23470-00-0
Price: US $1.00/KG
Min. Order: 1KG
Purity: 95.0-99.8%
Supply Ability: 1KG;5KG 10KG; 100KG
Release date: 2019-09-02

23470-00-0, 2-MONOPALMITINRelated Search:

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2-monopalmitoylglycerol (C16:0)

2-O-Hexadecanoylglycerol

2-O-Palmitoylglycerol

2-O-Palmitoyl-L-glycerol

Hexadecanoic acid [2-hydroxy-1-(hydroxymethyl)ethyl] ester

Palmitic acid 2-hydroxy-1-(hydroxymethyl)ethyl ester

2-Palmitoyl-rac-glycerol

2-(1,3-dihydroxypropan-2-yl)hexadecanoic acid compound with 1,3-dihydroxypropan-2-yl palmitate (1:1)

2-Hexadecanoylglycerol

1,3-Dihydroxypropan-2-yl palmitate

Glyceryl 2-monopalmitate

2-MONOOLEIN

2-Monohexadecanoylglycerol

2-Monopalmitoylglycerol

23470-00-0

C19H38O4

Fatty Acid Derivatives & Lipids

Glycerols

Cannabinoid receptor

SiChem