1,3-Dithiane
- Product Name
- 1,3-Dithiane
- CAS No.
- 505-23-7
- Chemical Name
- 1,3-Dithiane
- Synonyms
- 1,3-Dithian;M-DITHIANE;1,3-DITHIANE;Dithiane-1,3;1,3-Dithane;META-DITHIANE;1,3-Dithiane>1,3-Dithiane,97%;1,3-Dithiane,99%;1,3-Dithiane,98%
- CBNumber
- CB6223805
- Molecular Formula
- C4H8S2
- Formula Weight
- 120.24
- MOL File
- 505-23-7.mol
1,3-Dithiane Property
- Melting point:
- 52-54 °C (lit.)
- Boiling point:
- 207-208°C
- Density
- 1.062 (estimate)
- refractive index
- 1.5981 (estimate)
- Flash point:
- 195 °F
- storage temp.
- Inert atmosphere,Room Temperature
- form
- Crystals, Needles or Powder
- pka
- 31(at 25℃)
- color
- White to pale beige
- Odor
- at 0.01 % in propylene glycol. alliaceous roasted
- Odor Type
- alliaceous
- Water Solubility
- Soluble in benzene, ether, chloroform and terahydrofuran. Slightly soluble in water.
- Sensitive
- Hygroscopic
- BRN
- 102534
- InChIKey
- WQADWIOXOXRPLN-UHFFFAOYSA-N
- LogP
- 1.729 (est)
- CAS DataBase Reference
- 505-23-7(CAS DataBase Reference)
- NIST Chemistry Reference
- 1,3-Dithiane(505-23-7)
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H228Flammable solid
- Precautionary statements
-
P210Keep away from heat/sparks/open flames/hot surfaces. — No smoking.
P240Ground/bond container and receiving equipment.
P241Use explosion-proof electrical/ventilating/lighting/…/equipment.
P280Wear protective gloves/protective clothing/eye protection/face protection.
N-Bromosuccinimide Price
- Product number
- 157872
- Product name
- 1,3-Dithiane
- Purity
- 97%
- Packaging
- 5g
- Price
- $54.6
- Updated
- 2024/03/01
- Product number
- D0119
- Product name
- 1,3-Dithiane
- Purity
- >97.0%(GC)
- Packaging
- 5g
- Price
- $69
- Updated
- 2024/03/01
- Product number
- D0119
- Product name
- 1,3-Dithiane
- Purity
- >97.0%(GC)
- Packaging
- 25g
- Price
- $214
- Updated
- 2024/03/01
- Product number
- A10505
- Product name
- 1,3-Dithiane, 98%
- Packaging
- 5g
- Price
- $47.65
- Updated
- 2024/03/01
- Product number
- A10505
- Product name
- 1,3-Dithiane, 98%
- Packaging
- 25g
- Price
- $160.65
- Updated
- 2024/03/01
1,3-Dithiane Chemical Properties,Usage,Production
Chemical Properties
white to pale beige crystals, needles or powder
Uses
1,3-Dithiane is used in umpolung reactions such as the Corey-Seebach reaction. It acts as a reagent for the deoxygenation of sulfoxides to their corresponding sulfides. Further, it is used as a protecting group for carbonyl compounds used in organic synthesis. It serves as a useful labeled synthon. In addition to this, it is used in the preparation of 2-ethyl-[1,3]dithiane.
Definition
ChEBI: 1,3-dithiane is a dithiane.
Reactions
1,3-dithiane has 2 weakly acidic protons that can be removed and alkylation of the carbon is possible. Once alkylated, the 1,3-dithiane becomes a “protected” carbonyl as it can be hydrolyzed to the corresponding carbonyl structure. Alternatively, the 1,3-dithiane moiety may also be introduced by thioacetalisation of a carbonyl group, either using acid or Lewis acid catalysis, 12 or of a 1,1-dihalide (using transition metal catalysis).
Synthesis Reference(s)
Tetrahedron Letters, 29, p. 4477, 1988 DOI: 10.1016/S0040-4039(00)80527-4
General Description
1,3-Dithiane, a protected formaldehyde anion equivalent, serves as useful labeled synthon.
Purification Methods
Crystallise the 1,3-dithiane from 1.5 times its weight of MeOH at 0o, and sublime it at 40-50o/0.1mm. [Groel & Seebach Synthesis 357 1977, Beilstein 19/1 V 13.]
1,3-Dithiane Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from 1,3-Dithiane manufacturers
- Product
- 1,3-Dithiane 505-23-7
- Price
- US $2.00/kg
- Min. Order
- 1kg
- Purity
- 99%
- Supply Ability
- ask
- Release date
- 2018-12-22