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N'-NITROSONORNICOTINE

Product Name
N'-NITROSONORNICOTINE
CAS No.
16543-55-8
Chemical Name
N'-NITROSONORNICOTINE
Synonyms
NNN;(2S)-N’nitrosonornicotine;N-NITROSONORNICOTINE;1’-nitrosonornicotine;N'-NITROSONORNICOTINE;N'-NITROSONORNICOTINE;-Nitrosonornicotine-d4;N-nitroso nicotine (NNN);(S)-N’-Nitrosonornicotine
CBNumber
CB6227878
Molecular Formula
C9H11N3O
Formula Weight
177.2
MOL File
16543-55-8.mol
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N'-NITROSONORNICOTINE Property

Melting point:
47.1°C
Boiling point:
309.13°C (rough estimate)
Density 
1.1669 (rough estimate)
refractive index 
1.6500 (estimate)
storage temp. 
Hygroscopic, Refrigerator, Under Inert Atmosphere
solubility 
Chloroform (Slightly), Methanol (Slightly)
form 
Solid
pka
5.16±0.12(Predicted)
color 
Off-White to Pale Beige
Stability:
Stable, but air and light sensitive. Incompatible with oxidizing agents.
IARC
1 (Vol. Sup 7, 89, 100E) 2012
EPA Substance Registry System
N-Nitrosonornicotine (16543-55-8)
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Safety

Hazard Codes 
Xn
Risk Statements 
36/37/38-40
Safety Statements 
26-36
RIDADR 
2810
HazardClass 
6.1(b)
PackingGroup 
III
Hazardous Substances Data
16543-55-8(Hazardous Substances Data)
Toxicity
LD50 intraperitoneal in mouse: 1gm/kg
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H301Toxic if swalloed

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P301+P310IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.

P321Specific treatment (see … on this label).

P330Rinse mouth.

P405Store locked up.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
N-075
Product name
(±)-N′-Nitrosonornicotine (NNN) solution
Purity
1.0?mg/mLinmethanol,ampuleof1?mL,certifiedreferencematerial,Cerilliant?
Packaging
1mL
Price
$131
Updated
2022/05/15
TRC
Product number
N535001
Product name
(2S)-N’-Nitrosonornicotine
Packaging
10mg
Price
$185
Updated
2021/12/16
Medical Isotopes, Inc.
Product number
D34102
Product name
N?-Nitrosonornicotine-d4
Packaging
5mg
Price
$1250
Updated
2021/12/16
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N'-NITROSONORNICOTINE Chemical Properties,Usage,Production

Description

A nicotine alkaloid, this base has been detected in some Japanese cigarette tobaccos and also in Kirsu tobacco where it occurs in the fresh leaves that have been dried without fermentation. From these two sources it has been isolated at 1.1 and 1. 8 ppm levels respectively

Chemical Properties

white crystals

Uses

A tobacco alkaloid as risk factor of human cancer.

General Description

White crystalline flakes or yellow oil that solidifies on standing in the cold.

Air & Water Reactions

Insoluble in water.

Reactivity Profile

A nitrated amine, nicotine derivative. Amines are chemical bases. They neutralize acids to form salts plus water. These acid-base reactions are exothermic. The amount of heat that is evolved per mole of amine in a neutralization is largely independent of the strength of the amine as a base. Amines may be incompatible with isocyanates, halogenated organics, peroxides, phenols (acidic), epoxides, anhydrides, and acid halides. Flammable gaseous hydrogen is generated by amines in combination with strong reducing agents, such as hydrides.

Health Hazard

ACUTE/CHRONIC HAZARDS: When heated to decomposition it may emit toxic and hazardous fumes of NOx and COx.

Fire Hazard

Flash point data for N'-NITROSONORNICOTINE are not available; however, N'-NITROSONORNICOTINE is probably combustible.

Safety Profile

Confirmed carcinogen with experimental carcinogenic, neoplastigenic, and tumorigenic data. Low toxicity by intraperitoneal route. Mutation data reported. When heated to decomposition it emits toxic fumes of NOx. See also N-NITROSO COMPOUNDS.

Carcinogenicity

N-Nitrosonornicotine is reasonably anticipated to be a human carcinogen based on sufficient evidence of carcinogenicity from studies in experimental animals.

References

Bharadwaj et al., Gann., 66, 585 (1975)

N'-NITROSONORNICOTINE Preparation Products And Raw materials

Raw materials

Preparation Products

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N'-NITROSONORNICOTINE Suppliers

guoyungurui
Tel
18162595016; 18162595016
Email
3287908757@qq.com
Country
China
ProdList
10335
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J & K SCIENTIFIC LTD.
Tel
010-82848833 400-666-7788
Fax
86-10-82849933
Email
jkinfo@jkchemical.com
Country
China
ProdList
96815
Advantage
76
3B Pharmachem (Wuhan) International Co.,Ltd.
Tel
821-50328103-801 18930552037
Fax
86-21-50328109
Email
3bsc@sina.com
Country
China
ProdList
15839
Advantage
69
Chemsky(shanghai)International Co.,Ltd.
Tel
021-50135380
Email
shchemsky@sina.com
Country
China
ProdList
32321
Advantage
50
Spectrum Chemical Manufacturing Corp.
Tel
021-021-021-67601398-809-809-809 15221380277
Fax
021-57711696
Email
marketing_china@spectrumchemical.com
Country
China
ProdList
9658
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ChemStrong Scientific Co.,Ltd
Tel
0755-0755-66853366 13670046396
Fax
0755-28363542
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sales@chem-strong.com
Country
China
ProdList
18070
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Alta Scientific Co., Ltd.
Tel
022-6537-8550 15522853686
Fax
022-2532-9655
Email
sales@altasci.com.cn
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China
ProdList
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Shenzhen Newcore Chemical Technology Co., Ltd.
Tel
13612807752
Email
ncchemical@163.com
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China
ProdList
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Shandong Ono Chemical Co., Ltd.
Tel
0539-6362799 20)
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0539-6362799(To 20)
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China
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SuZhou Medinoah Co.,LTD.
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0512-69561983 13914027025
Fax
0512-69561982
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zhang_q@medinoah.com
Country
China
ProdList
3605
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16543-55-8, N'-NITROSONORNICOTINERelated Search:


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