Lufenuron

ChemicalBook > CAS DataBase List > Lufenuron

Product Name: Lufenuron
CAS No.: 103055-07-8
Chemical Name: Lufenuron
Synonyms: fluphenacur;Lufenuron 97%;Lufenuron@1000 μg/mL in Acetone;N-((2,5-Dichloro-4-(1,1,2,3,3,3-hexafluoropropoxy)phenyl)carbaMoyl)-2,6-difluorobenzaMide;LUFENURON;Lufenurin;cga-184,699;Lufenuron CRS;Lice mite urea;LufenuronStandard
CBNumber: CB6229074
Molecular Formula: C17H8Cl2F8N2O3
Formula Weight: 511.15
MOL File: 103055-07-8.mol

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Lufenuron Property

Melting point:: 174.1°
Density: 1.631±0.06 g/cm3(Predicted)
vapor pressure: <0.4 x10 -3 Pa (25 °C)
Flash point:: 170 °C
storage temp.: 0-6°C
solubility: 100mg/L in organic solvents at 20 ℃
form: Solid
Water Solubility: <0.06 mg l^-1(25 °C)
pka: 8.49±0.46(Predicted)
color: Off-white to light yellow
JECFA Number: 85
BRN: 8398291
InChIKey: PWPJGUXAGUPAHP-UHFFFAOYSA-N
LogP: 5.12 at 25℃
CAS DataBase Reference: 103055-07-8(CAS DataBase Reference)
EPA Substance Registry System: Benzamide, N-[[[2,5-dichloro-4-(1,1,2,3,3,3-hexafluoropropoxy)phenyl]amino]carbonyl]-2,6-difluoro- (103055-07-8)

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Safety

Hazard Codes: Xi;N,N,Xi
Risk Statements: 43-50/53
Safety Statements: 2-24-37-60-61
RIDADR: 3077
WGK Germany: 2
HazardClass: 9
PackingGroup: III
HS Code: 29242990
Toxicity: LD50 in rats (mg/kg): >2000 orally; LC50 in rats (mg/m3): >2350 (Buholzer)

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H317May cause an allergic skin reaction

H410Very toxic to aquatic life with long lasting effects

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P272Contaminated work clothing should not be allowed out of the workplace.

P273Avoid release to the environment.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P333+P313IF SKIN irritation or rash occurs: Get medical advice/attention.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 31662
Product name: Lufenuron
Purity: PESTANAL
Packaging: 100mg
Price: $103
Updated: 2024/03/01

Sigma-Aldrich

Product number: 1370779
Product name: Lufenuron
Purity: United States Pharmacopeia (USP) Reference Standard
Packaging: 200mg
Price: $436
Updated: 2024/03/01

Sigma-Aldrich

Product number: Y0001284
Product name: Lufenuron
Purity: European Pharmacopoeia (EP) Reference Standard
Packaging: y0001284
Price: $220
Updated: 2024/03/01

Sigma-Aldrich

Product number: Y0001261
Product name: Lufenuron for peak identification
Purity: European Pharmacopoeia (EP) Reference Standard
Packaging: y0001261
Price: $220
Updated: 2024/03/01

TRC

Product number: L473750
Product name: Lufenuron
Packaging: 1g
Price: $460
Updated: 2021/12/16

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Lufenuron Chemical Properties,Usage,Production

Description

Lufenuron is an insect development inhibitor of the benzoylphenyl urea class. It demonstrates activity against fleas that have fed on treated cats and dogs and become exposed to lufenuron in the host’s blood. Lufenuron also has activity by virtue of its presence in adult flea feces, leading to its ingestion by flea larvae. Both activities result in the production of eggs that are unable to hatch, causing significant reductions in flea larvae populations. The lipophilicity of lufenuron leads to its deposition in adipose tissues of animals from where it is slowly released into the bloodstream. This permits effective blood concentrations to be maintained throughout the recommended oral dosing interval of 1 month.

Uses

Lufenuron is used for the control of Lepidoptera and Coleoptera larvae on cotton, maize and vegetables, and of citrus whitefly and rust mites on citrus fruit. It is also used to control fleas on pets and cockroaches in houses.

Definition

ChEBI: Lufenuron is a benzoylurea insecticide, a dichlorobenzene, a N-acylurea, an aromatic ether and an organofluorine compound.

Flammability and Explosibility

Not classified

Pharmacology

Antiparasitic. Lufenuron is a benzoylurea insecticide. This class of insecticides was previously used on fruits to decrease damage by insects. Lufenuron (Program) has been used for prevention of flea infections in dogs and cats because it inhibits chitin synthesis. For this use, it has been given to dogs at a dose of 10 mg/kg every 30 days and to cats at a dose of 30 mg/kg every 30 days. It may also have some inhibition on fungal cell membranes because it inhibits the cell wall of fungi, which contain chitin, and other complex polysaccharides. Because of this property on fungal cell membranes, there has been interest in using lufenuron to treat dermatophytes in small animals. However, proven efficacy has been controversial. Well-controlled studies have not confirmed consistent efficacy for treating dermatophytes in animals.

Veterinary Drugs and Treatments

Lufenuron is approved for use in dogs and cats 6 weeks of age and older for the control of flea populations. The combination product of lufenuron and milbemycin (Sentinel?) is indicated for use in puppies and dogs 4 weeks and older for prevention and control flea populations, prevention of heartworm disease, control of adult hookworms, and the removal and control of adult roundworms and whipworms.
Lufeneron showed initial promise as a treatment for fungal infections, but the early enthusiasm has dampened considerably as efficacy appears doubtful.

Metabolic pathway

Only limited information is available in the open literature on the metabolism of lufenuron.

Degradation

Lufenuron is less stable at alkaline pH than under acidic conditions. The DT₅₀ at 25 °C is 160 days at pH 5,70 days at pH 7 and 32 days at pH 9 (PM).

Mode of action

Lufenuron has no systemic or translaminar effect. It is persistent with a transovarial effect. It may reduce the egg-Iaying rate or hinder the hatching process of embryos.

Lufenuron Preparation Products And Raw materials

Raw materials

Preparation Products

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Lufenuron Suppliers

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View Lastest Price from Lufenuron manufacturers

qingdao trust agri chemical co.,ltd

Product: Lufenuron 103055-07-8
Price: US $0.00/kg
Min. Order: 100kg
Purity: 98
Supply Ability: 10000
Release date: 2024-06-27

Hebei Zhuanglai Chemical Trading Co.,Ltd

Product: Lufenuron 103055-07-8
Price: US $100.00/kg
Min. Order: 1kg
Purity: 99
Supply Ability: 5000
Release date: 2024-04-24

Hebei Chuanghai Biotechnology Co., Ltd

Product: Lufenuron 103055-07-8
Price: US $25.00/ASSAYS
Min. Order: 100ASSAYS
Purity: 99.5%
Supply Ability: 100 mt
Release date: 2024-11-18

103055-07-8, LufenuronRelated Search:

Triflumuron Flufenoxuron Chlorine 4-Amino-3-chlorophenol 4-METHOXY-2-CHLOROANILINE Lufenuron 4-Amino-3-chlorophenol hydrochloride DULCIN 4-Amino-2,5-dichlorophenol METOXURON-MONOMETHYL 1,1,2,3,3,3-HEXAFLUOROPROPOXYBENZENE 3-CHLORO-4-ETHOXYANILINE (2,6-Difluoro-benzyl)-urea 3-CHLORO-4-DIFLUOROMETHOXY-PHENYLAMINE LUFENURON SOLUTION 100UG/ML IN TOLUENE 1ML LUFENURON SOLUTION 100UG/ML IN ACETONITRILE 1ML SALOR-INT L449725-1EA 1-(4-ETHOXYPHENYL)-3-METHYLUREA

fluphenacur

(rs)-1-[2,5-dichloro-4-(1,1,2,3,3,3-hexafluoropropoxyl)phenyl]3-(2,6-difluorobenzoyl)urea

cga-184,699

LUFENURON

Benzamide, N-2,5-dichloro-4-(1,1,2,3,3,3-hexafluoropropoxy)phenylaminocarbonyl-2,6-difluoro-

lufenuron (bsi,iso,inn)

(RS)-1-[2,5-Dichloro-4-(1,1,2,3,3,3-hexafluoropropoxy)phenyl]-3-(2,6-difluorobenzoyl)urea

N-[2,5-dichloro-4-(1,1,2,3,3,3-hexafluoropropoxy)-phenyl-aminocarbonyl]-2,6-difluorobenzamide

LUFENURON PESTANAL, 100 MG

1-[2,5-Dichloro-4-(1,1,2,3,3,3-hexafluoropropoxyl)phenyl]3-(2,6-difluorobenzoyl)urea

Lufenuron 100mg [103055-07-8]

FLUFENURON PESTANAL, 100 MG

N-((2,5-Dichloro-4-(1,1,2,3,3,3-hexafluoropropoxy)phenyl)carbaMoyl)-2,6-difluorobenzaMide

Lufenuron for peak identification

LufenuronStandard

Lufenuron 97%

N-((2,5-Dichloro-4-(1,1,2,3,3,3-hexafluoropropoxy)

Lufenuron @100 μg/mL in Methanol

Lufenuron Reference Material

Lufenuron for peak identification CRS

Lufenuron CRS

Lufenuron@1000 μg/mL in Acetone

Benzamide, N-2,5-dichloro-4-(1,1,2,3,3,3-hexafluoropropoxy)phenylaminocarbonyl-2,6-difluoro- lufenuron (bsi,iso,inn)

Lufenuron 5%EC acaricides for ticks agro chemical pesticide 103055-07-8

Lice mite urea

1-[2,5-Dichloro-4-(1,1,2,3,3,3-hexafluoropropoxy)phenyl]-3-(2,6-difluorobenzoyl)urea

Lufenuron (1370779)

Lufenuron Anhydrous

Lufenurin

Lufenuron 10.0 μg/ml Acetonitrile

lufenuron, 10 mM in DMSO

103055-07-8

C17H8CI2F8N2O3

C17H8Cl2F8N2O3

PROGRAM

103055-07-8