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Diethylacetamide

Product Name
Diethylacetamide
CAS No.
685-91-6
Chemical Name
Diethylacetamide
Synonyms
N,N-DIETHYLACETAMIDE;CH3CON(C2H5)2;diethylacetamide;ACETYL DIETHYLAMINE;n,n-diethyl-acetamid;n,n-diaethylacetamid;N-ACETYLDIETHYLAMINE;N,N-Diethylethanamide;acetamine,n,n-diethyl-;acetamide,n,n-diethyl-
CBNumber
CB6231642
Molecular Formula
C6H13NO
Formula Weight
115.17
MOL File
685-91-6.mol
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Diethylacetamide Property

Melting point:
<20 °C
Boiling point:
182-186 °C (lit.)
Density 
0.925 g/mL at 25 °C (lit.)
vapor pressure 
1.2 hPa (25 °C)
refractive index 
n20/D 1.440(lit.)
Flash point:
159 °F
storage temp. 
Store below +30°C.
solubility 
53.5g/l
pka
-0.41±0.70(Predicted)
form 
clear liquid
color 
Colorless to Almost colorless
Water Solubility 
Soluble in water.
BRN 
1209428
Dielectric constant
31.329999999999998
CAS DataBase Reference
685-91-6(CAS DataBase Reference)
NIST Chemistry Reference
Acetamide, N,N-diethyl-(685-91-6)
EPA Substance Registry System
N,N-Diethylacetamide (685-91-6)
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Safety

Hazard Codes 
Xn
Risk Statements 
20/21/22-36/37/38
Safety Statements 
26-27-36/37/39-45
WGK Germany 
3
RTECS 
AB7000000
TSCA 
Yes
HS Code 
29241900
Hazardous Substances Data
685-91-6(Hazardous Substances Data)
Toxicity
LD50 orally in Rabbit: 1500 mg/kg
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
8.03214
Product name
N,N-Diethylacetamide
Purity
for synthesis
Packaging
100mL
Price
$160
Updated
2024/03/01
Sigma-Aldrich
Product number
137529
Product name
N,N-Diethylacetamide
Purity
97%
Packaging
100g
Price
$156
Updated
2024/03/01
Sigma-Aldrich
Product number
8.03214
Product name
N,N-Diethylacetamide
Purity
for synthesis
Packaging
25mL
Price
$43.7
Updated
2023/06/20
TCI Chemical
Product number
D0461
Product name
N,N-Diethylacetamide
Purity
>99.0%(GC)
Packaging
25mL
Price
$37
Updated
2024/03/01
TCI Chemical
Product number
D0461
Product name
N,N-Diethylacetamide
Purity
>99.0%(GC)
Packaging
500mL
Price
$282
Updated
2024/03/01
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Diethylacetamide Chemical Properties,Usage,Production

Chemical Properties

clear colorless liquid

Uses

N,N-Diethylacetamide was used to investigate the spectroscopic properties ofN,N-diethyl-2-[(4-substituted)phenylsulfinyl] acetamides. It is commonly used as drug solvent.

Synthesis Reference(s)

Chemistry Letters, 18, p. 1983, 1989
The Journal of Organic Chemistry, 59, p. 4035, 1994 DOI: 10.1021/jo00094a004

General Description

N,N-Diethylacetamide is commonly used as drug solvent.

Hazard

Toxic by ingestion.

Safety Profile

Moderately toxic by ingestion and intraperitoneal routes. Questionable carcinogen with experimental tumorigenic data. Flammable when exposed to heat or flame. To fight fire, use foam, mist, CO2, dry chemical. When heated to decomposition it emits toxic fumes of NOx.

Purification Methods

Dissolve the amide in cyclohexane, shake with anhydrous BaO and then filter. The procedure is repeated three times, and the cyclohexane is distilled off at atmospheric pressure. The crude amide is also fractionally distilled three times from anhydrous BaO. [Beilstein 4 III 349.]

Diethylacetamide Preparation Products And Raw materials

Raw materials

Preparation Products

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Diethylacetamide Suppliers

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View Lastest Price from Diethylacetamide manufacturers

Hebei Yanxi Chemical Co., Ltd.
Product
Diethylacetamide 685-91-6
Price
US $30.00-16.00/kg
Min. Order
1kg
Purity
0.99
Supply Ability
20 tons
Release date
2023-09-22
Hebei Duling International Trade Co. LTD
Product
Diethylacetamide 685-91-6
Price
US $60.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
100 tons
Release date
2023-03-14
Hebei Zhuanglai Chemical Trading Co.,Ltd
Product
Diethylacetamide 685-91-6
Price
US $56.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
5000kg/week
Release date
2024-05-21

685-91-6, DiethylacetamideRelated Search:

N,N-Diethylhydroxylamine N,N-Diethylethylenediamine 2-Cyano-N,N-diethylacetamide N,N-Dimethylacetoacetamide N-Phthaloylglycine PHTHALIMIDOACETALDEHYDE DIETHYL ACETAL N-Hydroxyethylphthalimide 2-Chloro-N,N-diethylacetamide 1-(3-AMINOPROPYL)-2-PYRROLIDINONE 1-Benzyl-2-pyrrolidinone N-Acetylcaprolactam OXOTREMORINE N-(2-Bromoethyl)phthalimide 1-Ethyl-2-pyrrolidone Actinomycin D N-Ethylmaleimide N,N-Diethylcyanoacetamide N,N-Diethylacetoacetamide

  • n,n-diaethylacetamid
  • n,n-diethyl-acetamid
  • diethylacetamide
  • ACETIC ACID DIETHYLAMIDE
  • ACETYL DIETHYLAMINE
  • N-ACETYLDIETHYLAMINE
  • N,N-DIETHYLACETAMIDE
  • N,N-Diethylacetamide,99%
  • N,N-Diethylethanamide
  • acetamide,n,n-diethyl-
  • acetamine,n,n-diethyl-
  • aceticacid,amide,n,n-diethyl
  • CH3CON(C2H5)2
  • N,N-DIETHYLACETAMIDE FOR SYNTHESIS
  • N,N-Diethylacetamide&gt
  • Diethylacetamide ISO 9001：2015 REACH
  • N,N-Diethylacetamide, ≥ 99.0%
  • 685-91-6
  • CH3CONCH2CH32
  • Nitrogen Compounds
  • Organic Building Blocks
  • Protected Amines
  • Building Blocks