5,4'-DIHYDROXYFLAVONE

Product Name: 5,4'-DIHYDROXYFLAVONE
CAS No.: 6665-67-4
Chemical Name: 5,4'-DIHYDROXYFLAVONE
Synonyms: 5-Dihydroxyflavone;5,4'-DIHYDROXYFLAVONE;4',5-Dihydroxyflavone;4',5-Dihydroxyflavone;5-Hydroxy-2-(4-hydroxyphenyl);4'',5-Dihydroxyflavone, 10 mM in DMSO;5-Hydroxy-2-(4-hydroxyphenyl)-4H-chroMen-4-one;4H-1-Benzopyran-4-one, 5-hydroxy-2-(4-hydroxyphenyl)-;Lipoxygenase,Glucosidase,LOX,4',5-Dihydroxyflavone,4',5 Dihydroxyflavone,inhibit,Inhibitor,4',5Dihydroxyflavone
CBNumber: CB6234481
Molecular Formula: C15H10O4
Formula Weight: 254.24
MOL File: 6665-67-4.mol

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5,4'-DIHYDROXYFLAVONE Property

Melting point:: 239-240°C
Boiling point:: 486.0±45.0 °C(Predicted)
Density: 1.443±0.06 g/cm3(Predicted)
storage temp.: Store at -20°C
solubility: DMSO : ≥ 155 mg/mL (609.66 mM);Water : < 0.1 mg/mL (insoluble)
pka: 6.78±0.40(Predicted)
form: Solid
color: Light yellow to yellow

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

TRC

Product number: D679110
Product name: 4'',5-Dihydroxyflavone
Packaging: 1g
Price: $240
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FD66316
Product name: 4',5-Dihydroxyflavone
Packaging: 500mg
Price: $55
Updated: 2021/12/16

ChemScene

Product number: CS-0017766
Product name: 4',5-Dihydroxyflavone
Purity: 95.75%
Packaging: 100mg
Price: $90
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FD66316
Product name: 4',5-Dihydroxyflavone
Packaging: 1g
Price: $102
Updated: 2021/12/16

AK Scientific

Product number: W1616
Product name: 4',5-Dihydroxyflavone
Packaging: 10mg
Price: $117
Updated: 2021/12/16

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5,4'-DIHYDROXYFLAVONE Chemical Properties,Usage,Production

Uses

4',5-Dihydroxyflavone is a soybean LOX-1 and yeast α-Glucosidase inhibitor, with an Ki of 102.6 μM for soybean LOX-1 and an IC50 of 66 μM for yeast α-glucosidase. LOX-1 isshort for Lectin-like oxidized low-density lipoprotein receptor-1.

References

[1] Ribeiro D, et al. Inhibition of LOX by flavonoids: a structure-activity relationship study. Eur J Med Chem. 2014 Jan 24;72:137-45. DOI:10.1016/j.ejmech.2013.11.030
[2] Proen?a C, et al. α-Glucosidase inhibition by flavonoids: an in vitro and in silico structure-activity relationship study. J Enzyme Inhib Med Chem. 2017 Dec;32(1):1216-1228. DOI:10.1080/14756366.2017.1368503

5,4'-DIHYDROXYFLAVONE Preparation Products And Raw materials

Raw materials

Preparation Products

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6665-67-4, 5,4'-DIHYDROXYFLAVONERelated Search:

Rutin Quercetin 3,7,3',4'-TETRAMETHYLGOSSYPETIN MORIN AVICULARIN Quercitrin CHRYSOERIOL 3',5-DIHYDROXY-4',6,7-TRIMETHOXYFLAVONE Myricitrin ARTEMISININ Diosmin Rhamnetin 3,4'-DIMETHOXY-3',5,7-TRIHYDROXYFLAVONE Myricetin 5,7-DIHYDROXY-3',4',5'-TRIMETHOXYFLAVONE RHOIFOLIN EUPATORIN-5-METHYL ETHER Hyperoside

5,4'-DIHYDROXYFLAVONE

5-Hydroxy-2-(4-hydroxyphenyl)-4H-chroMen-4-one

5-Hydroxy-2-(4-hydroxyphenyl)

4H-1-Benzopyran-4-one, 5-hydroxy-2-(4-hydroxyphenyl)-

5-Dihydroxyflavone

Lipoxygenase,Glucosidase,LOX,4',5-Dihydroxyflavone,4',5 Dihydroxyflavone,inhibit,Inhibitor,4',5Dihydroxyflavone

4',5-Dihydroxyflavone

4'',5-Dihydroxyflavone, 10 mM in DMSO

4',5-Dihydroxyflavone

6665-67-4

Di-substituted Flavones