ChemicalBook > CAS DataBase List > trans-Dichlorodiamineplatinum(II)

trans-Dichlorodiamineplatinum(II)

Product Name
trans-Dichlorodiamineplatinum(II)
CAS No.
14913-33-8
Chemical Name
trans-Dichlorodiamineplatinum(II)
Synonyms
CPDC;CIS-DDP;PLATINOL;PLATINEX;BRIPLATIN;CISPLATYL;CISMAPLAT;nsc131558;TRANS-DDP;NEOPLATIN
CBNumber
CB6236182
Molecular Formula
Cl2H6N2Pt
Formula Weight
300.04
MOL File
14913-33-8.mol
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trans-Dichlorodiamineplatinum(II) Property

Melting point:
340 °C (dec.)(lit.)
storage temp. 
2-8°C
solubility 
DMSO (Sparingly)
form 
crystalline
pka
5.63
color 
yellow
Water Solubility 
Soluble in dimethylsulfoxide and dimethylformamide. Slightly soluble in water.
Exposure limits
ACGIH: TWA 0.002 mg/m3
NIOSH: IDLH 4 mg/m3; TWA 0.002 mg/m3
InChI
InChI=1S/2ClH.2H2N.Pt/h2*1H;2*1H2;/q;;2*-1;+4/p-2
InChIKey
DQLATGHUWYMOKM-UHFFFAOYSA-L
SMILES
[Pt+2](N)(N)([Cl-])[Cl-]
EPA Substance Registry System
Platinum, diamminedichloro-, (SP-4-1)- (14913-33-8)
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Safety

Hazard Codes 
T,Xn
Risk Statements 
45-25-41-68-42/43-40-23/24/25
Safety Statements 
53-26-39-45-36/37-24-23
RIDADR 
UN 3288 6.1/PG 2
WGK Germany 
3
RTECS 
TP2455000
10-21
HazardClass 
6.1(a)
PackingGroup 
II
HS Code 
28439000
Hazardous Substances Data
14913-33-8(Hazardous Substances Data)
Toxicity
mouse,LD50,intraperitoneal,27mg/kg (27mg/kg),Chemico-Biological Interactions. Vol. 5, Pg. 415, 1972.
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H317May cause an allergic skin reaction

H318Causes serious eye damage

H334May cause allergy or asthma symptoms or breathing difficulties if inhaled

Precautionary statements

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
Y0001018
Product name
Cisplatin impurity A
Purity
European Pharmacopoeia (EP) Reference Standard
Packaging
15 mg
Price
$225
Updated
2025/07/31
Sigma-Aldrich
Product number
PHR3252
Product name
Transplatin
Purity
pharmaceutical secondary standard, certified reference material
Packaging
50MG
Price
$588.05
Updated
2025/07/31
Sigma-Aldrich
Product number
P1525
Product name
trans-Platinum(II)diammine dichloride
Packaging
1g
Price
$335
Updated
2025/07/31
Sigma-Aldrich
Product number
BP544
Product name
Transplatin
Purity
British Pharmacopoeia (BP) Reference Standard
Packaging
25MG
Price
$272
Updated
2025/07/31
Sigma-Aldrich
Product number
1672803
Product name
Transplatin
Purity
United States Pharmacopeia (USP) Reference Standard
Packaging
25mg
Price
$1300
Updated
2025/07/31
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trans-Dichlorodiamineplatinum(II) Chemical Properties,Usage,Production

Chemical Properties

Yellow Powder or Crystal

Uses

Transplatin is the trans stereoisomer impurity of Cisplatin (C499500), an antineoplastic used in the treatment of sarcomas, some carcinomas, lymphomas, and germ cell tumors. Transplatin binds to DNA but does not exhibit the same useful pharmacological effect as its cis stereoisomer.

Uses

Transplatin is the trans stereoisomer impurity of trans-Dichlorodiamineplatinum(II), an antineoplastic used in the treatment of sarcomas, some carcinomas, lymphomas, and germ cell tumors. Transplatin binds to DNA but does not exhibit the same useful pharmacological effect as its cis stereoisomer.

Definition

ChEBI: A diamminedichloroplatinum compound in which the two ammine ligands and two chloro ligands are oriented in a trans planar configuration around the central platinum ion. Unlike its cis-isomer, cisplatin, it does not exhibit any useful pharmacological effect and is toxic.

Safety Profile

Poison by intraperitoneal route. Questionable carcinogen with experimental tumorigenic data. Human mutation data reported. See also PLATINUM COMPOUNDS. When heated to decomposition it emits toxic fumes of NOx and Cl-.

trans-Dichlorodiamineplatinum(II) Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from trans-Dichlorodiamineplatinum(II) manufacturers

ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD
Product
trans-Dichlorodiamineplatinum(II) 14913-33-8
Price
US $2.00-5.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
100kg
Release date
2025-06-19
WUHAN FORTUNA CHEMICAL CO., LTD
Product
trans-Dichlorodiamineplatinum(II) 14913-33-8
Price
US $0.00-0.00/G
Min. Order
10G
Purity
98%min
Supply Ability
30kg/month
Release date
2025-05-24
Career Henan Chemical Co
Product
trans-Dichlorodiamineplatinum(II) 14913-33-8
Price
US $7.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
1000kg
Release date
2019-08-31

14913-33-8, trans-Dichlorodiamineplatinum(II)Related Search:


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