trans-Dichlorodiamineplatinum(II)
- Product Name
- trans-Dichlorodiamineplatinum(II)
- CAS No.
- 14913-33-8
- Chemical Name
- trans-Dichlorodiamineplatinum(II)
- Synonyms
- CPDC;CIS-DDP;PLATINOL;PLATINEX;BRIPLATIN;CISPLATYL;CISMAPLAT;nsc131558;TRANS-DDP;NEOPLATIN
- CBNumber
- CB6236182
- Molecular Formula
- Cl2H4N2Pt
- Formula Weight
- 298.03
- MOL File
- 14913-33-8.mol
trans-Dichlorodiamineplatinum(II) Property
- Melting point:
- 340 °C (dec.)(lit.)
- storage temp.
- 2-8°C
- solubility
- DMSO (Sparingly)
- form
- crystalline
- color
- yellow
- Water Solubility
- Soluble in dimethylsulfoxide and dimethylformamide. Slightly soluble in water.
- Exposure limits
- ACGIH: TWA 0.002 mg/m3
NIOSH: IDLH 4 mg/m3; TWA 0.002 mg/m3 - EPA Substance Registry System
- Platinum, diamminedichloro-, (SP-4-1)- (14913-33-8)
Safety
- Hazard Codes
- T,Xn
- Risk Statements
- 45-25-41-68-42/43-40-23/24/25
- Safety Statements
- 53-26-39-45-36/37-24-23
- RIDADR
- UN 3288 6.1/PG 2
- WGK Germany
- 3
- RTECS
- TP2455000
- F
- 10-21
- HazardClass
- 6.1(a)
- PackingGroup
- II
- HS Code
- 28439000
- Hazardous Substances Data
- 14913-33-8(Hazardous Substances Data)
- Toxicity
- mouse,LD50,intraperitoneal,27mg/kg (27mg/kg),Chemico-Biological Interactions. Vol. 5, Pg. 415, 1972.
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Danger
- Hazard statements
-
H317May cause an allergic skin reaction
H318Causes serious eye damage
H334May cause allergy or asthma symptoms or breathing difficulties if inhaled
- Precautionary statements
-
P280Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352IF ON SKIN: wash with plenty of soap and water.
N-Bromosuccinimide Price
- Product number
- PHR3252
- Product name
- Transplatin
- Purity
- pharmaceutical secondary standard, certified reference material
- Packaging
- 50MG
- Price
- $576
- Updated
- 2024/03/01
- Product number
- P1525
- Product name
- trans-Platinum(II)diammine dichloride
- Packaging
- 1g
- Price
- $323
- Updated
- 2024/03/01
- Product number
- BP544
- Product name
- Transplatin
- Purity
- British Pharmacopoeia (BP) Reference Standard
- Packaging
- 25MG
- Price
- $266
- Updated
- 2024/03/01
- Product number
- 1672803
- Product name
- Transplatin
- Purity
- United States Pharmacopeia (USP) Reference Standard
- Packaging
- 25mg
- Price
- $1490
- Updated
- 2024/03/01
- Product number
- 010472
- Product name
- trans-Diamminedichloroplatinum(II), Pt 64.5% min
- Packaging
- 1g
- Price
- $211
- Updated
- 2024/03/01
trans-Dichlorodiamineplatinum(II) Chemical Properties,Usage,Production
Chemical Properties
Yellow Powder or Crystal
Uses
Transplatin is the trans stereoisomer impurity of Cisplatin (C499500), an antineoplastic used in the treatment of sarcomas, some carcinomas, lymphomas, and germ cell tumors. Transplatin binds to DNA but does not exhibit the same useful pharmacological effect as its cis stereoisomer.
Uses
Transplatin is the trans stereoisomer impurity of trans-Dichlorodiamineplatinum(II), an antineoplastic used in the treatment of sarcomas, some carcinomas, lymphomas, and germ cell tumors. Transplatin binds to DNA but does not exhibit the same useful pharmacological effect as its cis stereoisomer.
Definition
ChEBI: A diamminedichloroplatinum compound in which the two ammine ligands and two chloro ligands are oriented in a trans planar configuration around the central platinum ion. Unlike its cis-isomer, cisplatin, it does not exhibit any useful pharmacological effect and is toxic.
Safety Profile
Poison by intraperitoneal route. Questionable carcinogen with experimental tumorigenic data. Human mutation data reported. See also PLATINUM COMPOUNDS. When heated to decomposition it emits toxic fumes of NOx and Cl-.
trans-Dichlorodiamineplatinum(II) Preparation Products And Raw materials
Raw materials
Preparation Products
trans-Dichlorodiamineplatinum(II) Suppliers
View Lastest Price from trans-Dichlorodiamineplatinum(II) manufacturers
- Product
- trans-Dichlorodiamineplatinum(II) 14913-33-8
- Price
- US $0.00/G
- Min. Order
- 10G
- Purity
- 98%min
- Supply Ability
- 30kg/month
- Release date
- 2023-02-08
- Product
- trans-Dichlorodiamineplatinum(II) 14913-33-8
- Price
- US $7.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 1000kg
- Release date
- 2019-08-31