USNIC ACID

Product Name: USNIC ACID
CAS No.: 125-46-2
Chemical Name: USNIC ACID
Synonyms: usno;Usnic;USNEIN;USNIACIN;UNSICACID;SNIC ACID;Usnea acid;USNIC ACID;usninsaeure;2-USNICACID
CBNumber: CB6237422
Molecular Formula: C18H16O7
Formula Weight: 344.32
MOL File: 125-46-2.mol

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USNIC ACID Property

Melting point:: 200°C
alpha: D16 +509.4° (c = 0.697 in chloroform)
Boiling point:: 399.43°C (rough estimate)
Density: 1.2869 (rough estimate)
refractive index: 495 ° (C=0.7, CHCl3)
storage temp.: under inert gas (nitrogen or Argon) at 2-8°C
solubility: DMF:2.5(Max Conc. mg/mL);7.26(Max Conc. mM)
form: A crystalline solid
pka: 4.00±0.40(Predicted)
Merck: 9893
LogP: 2.880
CAS DataBase Reference: 125-46-2(CAS DataBase Reference)
EPA Substance Registry System: Usnic acid (125-46-2)

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Safety

Hazard Codes: T,N
Risk Statements: 25-50/53
Safety Statements: 22-24/25-61-60-45
RTECS: HP5270000
Hazardous Substances Data: 125-46-2(Hazardous Substances Data)
Toxicity: LD50 i.v. in mice: 25 mg/kg (Gottlieb, Shaw)

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

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N-Bromosuccinimide Price

Cayman Chemical

Product number: 22585
Product name: Usnic Acid
Purity: ≥98%
Packaging: 1g
Price: $25
Updated: 2024/03/01

Cayman Chemical

Product number: 22585
Product name: Usnic Acid
Purity: ≥98%
Packaging: 5g
Price: $61
Updated: 2024/03/01

Cayman Chemical

Product number: 22585
Product name: Usnic Acid
Purity: ≥98%
Packaging: 10g
Price: $107
Updated: 2024/03/01

Cayman Chemical

Product number: 22585
Product name: Usnic Acid
Purity: ≥98%
Packaging: 25g
Price: $202
Updated: 2024/03/01

TRC

Product number: U850153
Product name: UsnicAcid
Packaging: 10g
Price: $100
Updated: 2021/12/16

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USNIC ACID Chemical Properties,Usage,Production

Chemical Properties

Crystalline, yellow solid. Insoluble in water; slightly soluble in alcohol and ether.

Uses

Usnic acid is an enzyme inhibiting antitumor agent.

Uses

antibacterial

Uses

Usnic acid is a major metabolite from a number of lichen and fungal species and is perhaps one of the longest known microbial metabolites, first isolated in 1844. Usnic acid exhibits a broad range of biological activity, indeed it is easier to list the bioassays in which it does not exhibit activity. More often than not, potency is low and of limited value. Usnic acid is an important metabolite for dereplication in discovery research programs.

Definition

ChEBI: A member of the class of dibenzofurans that is dibenzo[b,d]furan-1(9bH)-one substituted by acetyl groups at positions 2 and 6, hydroxy groups at positions 3 and 7 and methyl groups at positions 8 and 9b.

Contact allergens

Usnic acid is a component of lichens, also used as a topical antibiotic. Allergic contact dermatitis from lichens occurs mainly occupationally in forestry and horticultural workers, and in lichen pickers.

Purification Methods

This very weak acid is the natural form which is recrystallised from Me2CO, MeOH or *C6H6. At 25o it is soluble in H2O (<0.01%), Me2CO (0.77%), EtOAc (0.88%), MeOCH2CH2OH (0.22%) and furfural (7.32%). [Curd & Robertson J Chem Soc 894 1937, Barton & Brunn J Chem Soc 603 1953, resolution: Dean et al. J Chem Soc 1250 1953, synthesis: Barton et al. J Chem Soc 538 1956, Beilstein 18/5 V 586.]

USNIC ACID Preparation Products And Raw materials

Raw materials

Preparation Products

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USNIC ACID Suppliers

Australia 1 China 247 Germany 3 India 5 Poland 2 South Korea 1 United Kingdom 7 United States 29 USA 1 Global 296

J & K SCIENTIFIC LTD.

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Email: market03@meryer.com
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Chembest Research Laboratories Limited

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Energy Chemical

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Shandong Xiya Chemical Co., Ltd

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Aktin Chemicals, Inc.

Tel: 86-28-85159085
Fax: 86-28-85152372
Email: info@aktinchem.com
Country: China
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View Lastest Price from USNIC ACID manufacturers

Ouhuang Engineering Materials (Hubei) Co., Ltd

Product: (±)-Usnic acid 125-46-2
Price: US $15.00/kg
Min. Order: 1kg
Purity: 99.912%
Supply Ability: 10ton
Release date: 2024-04-22

Ouhuang Engineering Materials (Hubei) Co., Ltd

Product: (±)-Usnic acid 125-46-2
Price: US $15.00/kg
Min. Order: 1kg
Purity: 99.912%
Supply Ability: 10ton
Release date: 2024-04-22

Ouhuang Engineering Materials (Hubei) Co., Ltd

Product: (±)-Usnic acid 125-46-2
Price: US $15.00/kg
Min. Order: 1kg
Purity: 99.912%
Supply Ability: 10ton
Release date: 2024-04-22

125-46-2, USNIC ACIDRelated Search:

2-tert-Butyl-4,6-dimethylphenol 2',4'-DIHYDROXY-3'-PROPYLACETOPHENONE 2,3-DIHYDRO-1-BENZOFURAN-7-CARBALDEHYDE 3-TERT-BUTYL-2-HYDROXYBENZALDEHYDE 2-N-HEXYLOXYBENZALDEHYDE 3-Methylphenethyl alcohol 3-METHOXY-2-CYCLOHEXEN-1-ONE 2-tert-Butyl-6-methylphenol 3-METHYL-1-PHENYL-2-BUTANONE USNIC ACID 5-TERT-BUTYL-2-HYDROXY-BENZALDEHYDE 3-METHYLPHENYLACETONE 2-(1,1-DIMETHYLPROPYL)PHENOL USNIC ACID, SODIUM SALT,USNIC ACID SODIUM,USNIC ACID SODIUM SALT, (+)-(RG) (+)-Usniacin (-)-USNIC ACID,l-Usnic acid,(-)-USNIC ACID 97% Dibenzofuran 3-(3,5-DIMETHYLPHENYL)-1-PROPENE

(+-)-uanicacid

2,6-diacetyl-1,

2,6-diacetyl-1,2,3,9b-tetrahydro-7,9-dihydroxy-8,9b-dimethyldibenzofuran-1,3-dione

2,6-diacetyl-7,9-dihydroxy-8,9b-dimethyl-1,3(2h,9bh)-dibenzofurandione

Usnic acid, usinic acid

10 GM and 25 GM

Carbonusninic acid

2,6-diacetyl-7,9-dihydroxy-8,9b-diMethyldibenzo[b,d]furan-1,3(2H,9bH)-dione

Usninic acid, Carbonusninic acid, Usno

Usnic acid/Usnic acid sodium

Usnea acid

D-2,6-Diacetyl-7

Pine nut acid

2,6-diacetyl-7,9-dihydroxy-8,9b-dimethyldibenzofuran-1,3-dione

3(2H,9bH)-Dibenzofurandione,2,6-diacetyl-7,9-dihydroxy-8,9b-dimethyl-1

9bh)-dibenzofurandione,2,6-diacetyl-7,9-dihydroxy-8,9b-dimethyl-3(2h

usninsaeure

usno

Usnic

1,3(2H,9bH)-Dibenzofurandione, 2,6-diacetyl-7,9-dihydroxy-8,9b-dimethyl-

USNIC ACID, (+)-(RG)

Usnein,Usniacin,Usninicacid

UNSICACID

2-hydroxy-6-methylanisic acid

USNINIC ACID

USNEIN

USNIACIN

USNIC ACID

Antibiotic lichen acid

2,6-DIACETYL-7,9-DIHYDROXY-8,9B-DIMETHYL-9BH-DIBENZOFURAN-1,3-DIONE

2-USNICACID

USNIC ACID USP/EP/BP

SNIC ACID

Usnic Acid, ≥ 98.0%

125-46-2

C18H16O7

CH3OC6H2OHCH3COOH

Inhibitors

231-456-0

chemical reagent

pharmaceutical intermediate

phytochemical

reference standards from Chinese medicinal herbs (TCM).

standardized herbal extract

Miscellaneous Natural Products