ChemicalBook > CAS DataBase List > USNIC ACID

USNIC ACID

Product Name
USNIC ACID
CAS No.
125-46-2
Chemical Name
USNIC ACID
Synonyms
usno;Usnic;USNEIN;USNIACIN;UNSICACID;SNIC ACID;Usnea acid;USNIC ACID;usninsaeure;2-USNICACID
CBNumber
CB6237422
Molecular Formula
C18H16O7
Formula Weight
344.32
MOL File
125-46-2.mol
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USNIC ACID Property

Melting point:
200°C
alpha 
D16 +509.4° (c = 0.697 in chloroform)
Boiling point:
399.43°C (rough estimate)
Density 
1.2869 (rough estimate)
refractive index 
495 ° (C=0.7, CHCl3)
storage temp. 
under inert gas (nitrogen or Argon) at 2-8°C
solubility 
DMF:2.5(Max Conc. mg/mL);7.26(Max Conc. mM)
form 
A crystalline solid
pka
4.00±0.40(Predicted)
Merck 
9893
LogP
2.880
CAS DataBase Reference
125-46-2(CAS DataBase Reference)
EPA Substance Registry System
Usnic acid (125-46-2)
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Safety

Hazard Codes 
T,N
Risk Statements 
25-50/53
Safety Statements 
22-24/25-61-60-45
RTECS 
HP5270000
Hazardous Substances Data
125-46-2(Hazardous Substances Data)
Toxicity
LD50 i.v. in mice: 25 mg/kg (Gottlieb, Shaw)
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

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N-Bromosuccinimide Price

Cayman Chemical
Product number
22585
Product name
Usnic Acid
Purity
≥98%
Packaging
1g
Price
$25
Updated
2024/03/01
Cayman Chemical
Product number
22585
Product name
Usnic Acid
Purity
≥98%
Packaging
5g
Price
$61
Updated
2024/03/01
Cayman Chemical
Product number
22585
Product name
Usnic Acid
Purity
≥98%
Packaging
10g
Price
$107
Updated
2024/03/01
Cayman Chemical
Product number
22585
Product name
Usnic Acid
Purity
≥98%
Packaging
25g
Price
$202
Updated
2024/03/01
TRC
Product number
U850153
Product name
UsnicAcid
Packaging
10g
Price
$100
Updated
2021/12/16
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USNIC ACID Chemical Properties,Usage,Production

Chemical Properties

Crystalline, yellow solid. Insoluble in water; slightly soluble in alcohol and ether.

Uses

Usnic acid is an enzyme inhibiting antitumor agent.

Uses

antibacterial

Uses

Usnic acid is a major metabolite from a number of lichen and fungal species and is perhaps one of the longest known microbial metabolites, first isolated in 1844. Usnic acid exhibits a broad range of biological activity, indeed it is easier to list the bioassays in which it does not exhibit activity. More often than not, potency is low and of limited value. Usnic acid is an important metabolite for dereplication in discovery research programs.

Definition

ChEBI: A member of the class of dibenzofurans that is dibenzo[b,d]furan-1(9bH)-one substituted by acetyl groups at positions 2 and 6, hydroxy groups at positions 3 and 7 and methyl groups at positions 8 and 9b.

Contact allergens

Usnic acid is a component of lichens, also used as a topical antibiotic. Allergic contact dermatitis from lichens occurs mainly occupationally in forestry and horticultural workers, and in lichen pickers.

Purification Methods

This very weak acid is the natural form which is recrystallised from Me2CO, MeOH or *C6H6. At 25o it is soluble in H2O (<0.01%), Me2CO (0.77%), EtOAc (0.88%), MeOCH2CH2OH (0.22%) and furfural (7.32%). [Curd & Robertson J Chem Soc 894 1937, Barton & Brunn J Chem Soc 603 1953, resolution: Dean et al. J Chem Soc 1250 1953, synthesis: Barton et al. J Chem Soc 538 1956, Beilstein 18/5 V 586.]

USNIC ACID Preparation Products And Raw materials

Raw materials

Preparation Products

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USNIC ACID Suppliers

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View Lastest Price from USNIC ACID manufacturers

BINBO BIOLOGICAL CO.,LTD
Product
Usnic Acid 125-46-2
Price
US $0.00/kg
Min. Order
1kg
Purity
98%
Supply Ability
1000 kg
Release date
2024-04-29
Ouhuang Engineering Materials (Hubei) Co., Ltd
Product
(±)-Usnic acid 125-46-2
Price
US $15.00/kg
Min. Order
1kg
Purity
99.912%
Supply Ability
10ton
Release date
2024-04-22
Ouhuang Engineering Materials (Hubei) Co., Ltd
Product
(±)-Usnic acid 125-46-2
Price
US $15.00/kg
Min. Order
1kg
Purity
99.912%
Supply Ability
10ton
Release date
2024-04-22

125-46-2, USNIC ACIDRelated Search:

2-tert-Butyl-4,6-dimethylphenol 2',4'-DIHYDROXY-3'-PROPYLACETOPHENONE 2,3-DIHYDRO-1-BENZOFURAN-7-CARBALDEHYDE 3-TERT-BUTYL-2-HYDROXYBENZALDEHYDE 2-N-HEXYLOXYBENZALDEHYDE 3-Methylphenethyl alcohol 3-METHOXY-2-CYCLOHEXEN-1-ONE 2-tert-Butyl-6-methylphenol 3-METHYL-1-PHENYL-2-BUTANONE USNIC ACID 5-TERT-BUTYL-2-HYDROXY-BENZALDEHYDE 3-METHYLPHENYLACETONE 2-(1,1-DIMETHYLPROPYL)PHENOL USNIC ACID, SODIUM SALT,USNIC ACID SODIUM,USNIC ACID SODIUM SALT, (+)-(RG) (+)-Usniacin (-)-USNIC ACID,l-Usnic acid,(-)-USNIC ACID 97% Dibenzofuran 3-(3,5-DIMETHYLPHENYL)-1-PROPENE

  • (+-)-uanicacid
  • 2,6-diacetyl-1,
  • 2,6-diacetyl-1,2,3,9b-tetrahydro-7,9-dihydroxy-8,9b-dimethyldibenzofuran-1,3-dione
  • 2,6-diacetyl-7,9-dihydroxy-8,9b-dimethyl-1,3(2h,9bh)-dibenzofurandione
  • Usnic acid, usinic acid
  • 10 GM and 25 GM
  • Carbonusninic acid
  • 2,6-diacetyl-7,9-dihydroxy-8,9b-diMethyldibenzo[b,d]furan-1,3(2H,9bH)-dione
  • Usninic acid, Carbonusninic acid, Usno
  • Usnic acid/Usnic acid sodium
  • Usnea acid
  • D-2,6-Diacetyl-7
  • Pine nut acid
  • 2,6-diacetyl-7,9-dihydroxy-8,9b-dimethyldibenzofuran-1,3-dione
  • 3(2H,9bH)-Dibenzofurandione,2,6-diacetyl-7,9-dihydroxy-8,9b-dimethyl-1
  • 9bh)-dibenzofurandione,2,6-diacetyl-7,9-dihydroxy-8,9b-dimethyl-3(2h
  • usninsaeure
  • usno
  • Usnic
  • 1,3(2H,9bH)-Dibenzofurandione, 2,6-diacetyl-7,9-dihydroxy-8,9b-dimethyl-
  • USNIC ACID, (+)-(RG)
  • Usnein,Usniacin,Usninicacid
  • UNSICACID
  • 2-hydroxy-6-methylanisic acid
  • USNINIC ACID
  • USNEIN
  • USNIACIN
  • USNIC ACID
  • Antibiotic lichen acid
  • 2,6-DIACETYL-7,9-DIHYDROXY-8,9B-DIMETHYL-9BH-DIBENZOFURAN-1,3-DIONE
  • 2-USNICACID
  • USNIC ACID USP/EP/BP
  • SNIC ACID
  • Usnic Acid, ≥ 98.0%
  • 125-46-2
  • C18H16O7
  • CH3OC6H2OHCH3COOH
  • Inhibitors
  • 231-456-0
  • chemical reagent
  • pharmaceutical intermediate
  • phytochemical
  • reference standards from Chinese medicinal herbs (TCM).
  • standardized herbal extract
  • Miscellaneous Natural Products