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ISOCORYDINE HYDROCHLORIDE

Product Name
ISOCORYDINE HYDROCHLORIDE
CAS No.
475-67-2
Chemical Name
ISOCORYDINE HYDROCHLORIDE
Synonyms
luteanin;LUTEANINE;artabotrin;Aids138466;Uzokoridin;Isocorydine;Aids-138466;d-isocorydine;l-(+)-isocorydine;S-ISOCORYDINE (+)
CBNumber
CB6238999
Molecular Formula
C20H23NO4
Formula Weight
341.4
MOL File
475-67-2.mol
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ISOCORYDINE HYDROCHLORIDE Property

Melting point:
216-220 °C(lit.)
alpha 
D20 +195° (chloroform)
Boiling point:
477.03°C (rough estimate)
Density 
1.2064 (rough estimate)
refractive index 
1.5614 (estimate)
solubility 
Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
form 
Cryst.
pka
9.41±0.20(Predicted)
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Safety

WGK Germany 
3
RTECS 
CE1057950
Toxicity
LD50 intraperitoneal in mouse: 104mg/kg
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Cayman Chemical
Product number
30101
Product name
Isocorydine
Packaging
10mg
Price
$56
Updated
2024/03/01
Cayman Chemical
Product number
30101
Product name
Isocorydine
Packaging
25mg
Price
$116
Updated
2024/03/01
Cayman Chemical
Product number
30101
Product name
Isocorydine
Packaging
5mg
Price
$37
Updated
2024/03/01
Cayman Chemical
Product number
30101
Product name
Isocorydine
Packaging
50mg
Price
$178
Updated
2024/03/01
Usbiological
Product number
361810
Product name
Isocorydine
Packaging
20mg
Price
$546
Updated
2021/12/16
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ISOCORYDINE HYDROCHLORIDE Chemical Properties,Usage,Production

Description

Isocorydine is an aporphine alkaloid that has been found in A. squamosa that has vasodilatory and anticancer activities. It reduces the action potential duration and increases the effective refractory period in isolated canine Purkinje fibers when used at a concentration of 30 μM. Isocorydine induces relaxation of norepinephrine-precontracted isolated rabbit aortic strips with an EC50 value of 12.6 μM. It is cytotoxic to A549 lung cancer cells (IC50 = 197.7 μM), as well as Huh7, HepG2, SNU-449, and SNU-387 hepatic cancer cells (IC50s = 161.3, 148, 262.2, and 254.1 μg/ml, respectively). Isocorydine, in combination with doxorubicin, reduces tumor growth in a Huh7 mouse xenograft model.

Uses

Isocorydine Hydrochloride is the hydrochloric acid of Isocorydine(I797000) which is an alkaloid inhibitor of eukaryotic kinases.

Uses

sedative, cholinergic

Uses

Isocorydine is an alkaloid inhibitor of eukaryotic kinases.

Definition

ChEBI: Isocorydine is an aporphine alkaloid.

target

Dopamine Receptor | P450 (e.g. CYP17)

References

See Isocorydine

ISOCORYDINE HYDROCHLORIDE Preparation Products And Raw materials

Raw materials

Preparation Products

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ISOCORYDINE HYDROCHLORIDE Suppliers

China 124 Germany 1 Switzerland 3 Ukraine 1 United Kingdom 7 United States 16 Global 152
Carbosynth
Tel
--
Fax
--
Email
sales@carbosynth.com
Country
United Kingdom
ProdList
6005
Advantage
58
MOLEKULA Ltd.
Tel
--
Fax
--
Email
kevinbanks@molekula.com
Country
United Kingdom
ProdList
6140
Advantage
66
CARBONE SCIENTIFIC CO.,LTD
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Email
sales@carbonesci.com
Country
United Kingdom
ProdList
6666
Advantage
30
Apin Chemicals Limited (UK)
Tel
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Email
info@apinchemicals.com
Country
United Kingdom
ProdList
6184
Advantage
60
ETA SCIENTIFIC Co.,Ltd
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Email
sales@etascientific.com
Country
United Kingdom
ProdList
6090
Advantage
34
Sequoia Research Products Ltd.
Tel
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Fax
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Email
sales@seqchem.com
Country
United Kingdom
ProdList
3113
Advantage
69
Apin Chemicals Ltd.
Tel
--
Fax
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Email
info@apinchemicals.com
Country
United Kingdom
ProdList
6807
Advantage
42
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View Lastest Price from ISOCORYDINE HYDROCHLORIDE manufacturers

Shanghai Standard Technology Co., Ltd.
Product
Isocorydine 475-67-2
Price
US $0.00/mg
Min. Order
20mg
Purity
≥98%(HPLC)
Supply Ability
100 g
Release date
2020-08-19
Career Henan Chemical Co
Product
ISOCORYDINE HYDROCHLORIDE 475-67-2
Price
US $9.80/KG
Min. Order
1KG
Purity
≥98%
Supply Ability
20 tons
Release date
2020-01-09

475-67-2, ISOCORYDINE HYDROCHLORIDERelated Search:

(S)-1-(3,4-Dimethoxyphenyl)ethylamine 2-METHOXYBIPHENYL 1-BIPHENYL-2-YL-N-METHYLMETHYLAMINE 4-CHLORO-2-FLUOROBENZYLAMINE HYDROCHLORIDE ISOCORYDINE HYDROCHLORIDE ISOCORYDINE HYDROCHLORIDE (S)-1,2,3,4-tetrahydro-1-[(3-hydroxy-4-methoxyphenyl)methyl]-6-methoxy-2-methylisoquinolin-7-ol 2,6-Dimethylbenzylamine 3,4,5-TRIMETHYLPHENOL 2,2'-Biphenol 3-[(1S)-1-(Dimethylaminoethyl)]phenol (S)-7-METHOXY-1-METHYL-1,2,3,4-TETRAHYDRO-ISOQUINOLIN-6-OL (R)-4-(1-Aminoethyl)phenol (S)-hydroxybutanedioate salt SALSOLIDINE 2,6-DIMETHYL-4-HYDROXYBENZYLAMINE (S)-o-Methyl-a-phenylethylamine 8-methyl-1,2,3,4-tetrahydroisoquinoline 6,7-DIMETHOXY-1-METHYL-1,2,3,4-TETRAHYDROISOQUINOLINE

  • LUTEANINE
  • LUTEANINE HYDROCHLORIDE
  • 1,2,10-trimethoxy-6a-alpha-aporphin-11-o
  • 4h-dibenzo(de,g)quinolin-11-ol,5,6,6a,7-tetrahydro-1,2,10-trimethoxy-6-methy
  • artabotrin
  • d-isocorydine
  • l-(+)-isocorydine
  • luteanin
  • luteanine(aporphine)
  • D-ISOCORYDINE HYDROCHLORIDE
  • (+)-ISOCORYDINE HCL
  • ISOCORYDINE HCL, (+)-
  • (+)-ISOCORYDINE HYDROCHLORIDE
  • ISOCORYDINE HYDROCHLORIDE
  • (6aS)-5,6,6a,7-Tetrahydro-1,2,10-trimethoxy-6-methyl-4H-dibenzo[de,g]quinolin-11-ol
  • 11-HYDROXY-1,2,10-TRIMETHOXYAPORPHINE
  • 11-HYDROXY-1,2,10-TRIMETHOXYAPORPHINE HYDROCHLORIDE
  • (+)-Isocorynoline hydrochloride
  • (6aS)-5,6,6a,7-Tetrahydro-1,2,10-trimethoxy-6-methyl-4H-dibenzo[de,g]quinoline-11-ol
  • [6aS,(+)]-5,6,6a,7-Tetrahydro-1,2,10-trimethoxy-6-methyl-4H-dibenzo[de,g]quinoline-11-ol
  • Isocorydine
  • S-ISOCORYDINE (+)
  • 1,2,10-Trimethoxy-6-methyl-5,6,6A,7-tetrahydro-4H-dibenzo[de,G]quinolin-11-ol
  • Aids138466
  • Aids-138466
  • Aporphin-11-ol, 1,2,10-trimethoxy-
  • (+)-isocorynoline
  • Uzokoridin
  • 4H-Dibenzo[de,g]quinolin-11-ol, 5,6,6a,7-tetrahydro-1,2,10-trimethoxy-6-methyl-, (6aS)-
  • Artabotrin|||S-Isocorydine(+)|||Luteanin|||Uzokoridin|||(+)-Isocorynoline
  • 475-67-2
  • Analytical Chromatography Product Catalog
  • Analytical Standards
  • Asymmetric Synthesis
  • Chiral Building Blocks
  • Others
  • Drug Standards
  • Chromatography
  • Forensic and Veterinary Standards
  • Heterocyclic Building Blocks
  • Inhibitors
  • Miscellaneous Natural Products
  • Alkaloids