(+)-AJ 76 HYDROCHLORIDE

Product Name: (+)-AJ 76 HYDROCHLORIDE
CAS No.: 85379-09-5
Chemical Name: (+)-AJ 76 HYDROCHLORIDE
Synonyms: AJ-76;U-80278A;(+)-AJ76 HCL;(+)-AJ 76 HYDROCHLORIDE;5-methoxy-1-methyl-2-(n-propylamino)tetralin;N-Propyl-1α-methyl-5-methoxytetralin-2α-amine;(1S,2R)-5-methoxy-1-methyl-2-(propylamino)tetralin;(1S,2R)-CIS-5-METHOXY-1-METHYL-2-(N-PROPYLAMINO)-TETRALIN HCL;(1S,2R)-cis-5-Methoxy-1-methyl-2-(N-propylamino)tetralinehydrochloride;(1S,2R)-CIS-5-METHOXY-1-METHYL-2-(N-PROPYLAMINO)TETRALIN HYDROCHLORIDE
CBNumber: CB6241438
Molecular Formula: C15H23NO
Formula Weight: 233.35
MOL File: 85379-09-5.mol

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(+)-AJ 76 HYDROCHLORIDE Property

Boiling point:: 345.3±42.0 °C(Predicted)
Density: 1.00±0.1 g/cm3(Predicted)
storage temp.: Store at RT
solubility: Soluble to 10 mM in H2O
form: White crystalline solid.
pka: 10.28±0.40(Predicted)

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

TRC

Product number: A965323
Product name: AJ-76
Packaging: 10mg
Price: $115
Updated: 2021/12/16

ApexBio Technology

Product number: B6403
Product name: (+)-AJ76hydrochloride
Packaging: 10mg
Price: $257
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: API0009809
Product name: (+)-AJ 76 HYDROCHLORIDE
Purity: 95.00%
Packaging: 10MG
Price: $716.1
Updated: 2021/12/16

ApexBio Technology

Product number: B6403
Product name: (+)-AJ76hydrochloride
Packaging: 50mg
Price: $1083
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: API0009809
Product name: (+)-AJ 76 HYDROCHLORIDE
Purity: 95.00%
Packaging: 100MG
Price: $1686.3
Updated: 2021/12/16

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(+)-AJ 76 HYDROCHLORIDE Chemical Properties,Usage,Production

Uses

(+)-AJ 76 Hydrochloride was used in asymmetric synthesis of methoxymethyl(di-n-propylamino)tetralin hydrochloride.

Definition

ChEBI: A secondary amino compound that consists of tetralin bearing methyl, propylamino and methoxy groups at positions 1, 2 and 5 respectively. Dopamine receptor antagonist with preferential action at presynaptic receptors (pKi values are 6.95, 6.67, 6.37, 6.21 nd 6.07 at hD3. hD4, hD2S, hD2L and rD2 receptors respectively).

Biological Activity

Dopamine receptor antagonist with preferential action at presynaptic receptors (pK i values are 6.95, 6.67, 6.37, 6.21 and 6.07 at hD 3 . hD 4 , hD 2S , hD 2L and rD 2 receptors respectively).

References

[1]. kullingsjö h, carlsson a, svensson k. effects of repeated administration of the preferential dopamine autoreceptor antagonist, (+)-aj76, on locomotor activity and brain da metabolism in the rat. eur j pharmacol, 1991, 205(3): 241-246.
[2]. piercey mf, lum jt, hoffmann we, et al. antagonism of cocaine's pharmacological effects by the stimulant dopaminergic antagonists, (+)-aj76 and (+)-uh232. brain res, 1992; 588(2): 217-222.
[3]. waters n, hansson l, löfberg l, et al. intracerebral infusion of (+)-aj76 and (+)-uh232: effects on dopamine release and metabolism in vivo. eur j pharmacol, 1994, 251(2-3): 181-190.

(+)-AJ 76 HYDROCHLORIDE Preparation Products And Raw materials

Raw materials

Preparation Products

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(+)-AJ 76 HYDROCHLORIDE Suppliers

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85379-09-5, (+)-AJ 76 HYDROCHLORIDERelated Search:

Vanoxerine dihydrochloride Clozapine REMOXIPRIDE HYDROCHLORIDE CLOTHIAPINE BTCP HCL Bromocriptine mesylate 2-phenyl-4-azabicyclo[5.4.0]undeca-7,9,11-triene-9,10-diol U-99194 MALEATE R-(-)-7-Chloro-8-hydroxy-3-methyl-1-phenyl-2,3,4,5-tetrahydro-1H-3-benzazepine, hydrochloride LE 300 (RS)-TRANS-7-HYDROXY-2-[N-PROPYL-N-(3'-IODO-2'-PROPENYL)AMINO]TETRALIN MALEATE (R)-2-AMINOTETRALIN (5-METHOXY-1,2,3,4-TETRAHYDRO-NAPHTHALEN-2-YL)-PROPYL-AMINE HYDROCHLORIDE (R)-(+)-5-METHOXY 2-AMINOTETRALIN ((R)-5-METHOXY-1,2,3,4-TETRAHYDRO-NAPHTHALEN-2-YL)-PROPYL-AMINE HYDROCHLORIDE 2-PROPYLAMINO-5-METHOXYTETRALIN (+)-AJ 76 HYDROCHLORIDE (+)-UH 232 MALEATE

AJ-76

(+)-AJ76 HCL

(+)-AJ 76 HYDROCHLORIDE

(1S,2R)-CIS-5-METHOXY-1-METHYL-2-(N-PROPYLAMINO)-TETRALIN HCL

(1S,2R)-CIS-5-METHOXY-1-METHYL-2-(N-PROPYLAMINO)TETRALIN HYDROCHLORIDE

(1S,2R)-cis-5-Methoxy-1-methyl-2-(N-propylamino)tetralinehydrochloride

5-methoxy-1-methyl-2-(n-propylamino)tetralin

(1S)-1,2,3,4-Tetrahydro-5-methoxy-1α-methyl-N-propyl-2α-naphthalenamine

(1S,2R)-1,2,3,4-Tetrahydro-5-methoxy-1-methyl-N-propyl-2-naphthalenamine

N-Propyl-1α-methyl-5-methoxytetralin-2α-amine

U-80278A

(1S,2R)-5-methoxy-1-methyl-2-(propylamino)tetralin

2-Naphthalenamine, 1,2,3,4-tetrahydro-5-methoxy-1-methyl-N-propyl-, (1S,2R)-

(1S,2R)-5-methoxy-1-methyl-N-propyl-1,2,3,4-tetrahydronaphthalen-2-amine

85379-09-5