ISOMENTHONE Property

FEMA 

3460 | D,L-ISOMENTHONE

color 

A colourless slightly oily liquid

Safety

Toxicity

The acute dermal LD 5 0 in rabbits was reported as > 5 ml/kg (Levenstein, 1973).

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H317May cause an allergic skin reaction

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P272Contaminated work clothing should not be allowed out of the workplace.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P321Specific treatment (see … on this label).

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P333+P313IF SKIN irritation or rash occurs: Get medical advice/attention.

P362Take off contaminated clothing and wash before reuse.

P363Wash contaminated clothing before reuse.

P501Dispose of contents/container to..…

ISOMENTHONE Chemical Properties,Usage,Production

Occurrence

d-Isomenthone has been reported to have been isolated from Micromeria abissinica Benth., Pelargonium tomentosum Jacquin and others. /-Isomenthone has been identified in Reunion geranium, Pelargonium capitatum and others (FenaroWs Handbook of Flavor Ingredients, 1971).

Preparation

By hydrogénation of piperitone.

Definition

ChEBI: (-)-isomenthone is an isomenthone. It is an enantiomer of a (+)-isomenthone.

Metabolism

d-Isomenthone undergoes reduction in the rabbit, since d-isomethylglucuronide is excreted in the urine. The other possible reduction product, d-neoisomenthol is not excreted (Williams, 1959).