2,6-DICHLORO-4-METHOXY-PYRIDINE
- Product Name
- 2,6-DICHLORO-4-METHOXY-PYRIDINE
- CAS No.
- 17228-75-0
- Chemical Name
- 2,6-DICHLORO-4-METHOXY-PYRIDINE
- Synonyms
- 4-Methoxy-2,6-dichloropyridine;2,6-DICHLORO-4-METHOXY-PYRIDINE;Pyridine, 2,6-dichloro-4-methoxy-;2,6-Dichloro-4-methoxypyridine 99%
- CBNumber
- CB62446547
- Molecular Formula
- C6H5Cl2NO
- Formula Weight
- 178.02
- MOL File
- 17228-75-0.mol
2,6-DICHLORO-4-METHOXY-PYRIDINE Property
- Boiling point:
- 255.0±35.0 °C(Predicted)
- Density
- 1.363±0.06 g/cm3(Predicted)
- storage temp.
- Inert atmosphere,Room Temperature
- pka
- -0.91±0.10(Predicted)
- form
- solid
- color
- White to off-white
- InChI
- InChI=1S/C6H5Cl2NO/c1-10-4-2-5(7)9-6(8)3-4/h2-3H,1H3
- InChIKey
- MMQWWYZZOZBFHY-UHFFFAOYSA-N
- SMILES
- C1(Cl)=NC(Cl)=CC(OC)=C1
Safety
- HS Code
- 2933399990
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P280Wear protective gloves/protective clothing/eye protection/face protection.
P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- D437270
- Product name
- 2,6-Dichloro-4-methoxypyridine
- Packaging
- 100mg
- Price
- $60
- Updated
- 2021/12/16
- Product number
- CS-W021523
- Product name
- 2,6-Dichloro-4-methoxypyridine
- Purity
- 99.37%
- Packaging
- 1g
- Price
- $42
- Updated
- 2021/12/16
- Product number
- 4H56-5-9B
- Product name
- 2,6-Dichloro-4-methoxypyridine
- Packaging
- 1g
- Price
- $48
- Updated
- 2021/12/16
- Product number
- FD144045
- Product name
- 2,6-Dichloro-4-methoxypyridine
- Packaging
- 250mg
- Price
- $52.5
- Updated
- 2021/12/16
- Product number
- Y7807
- Product name
- 2,6-Dichloro-4-methoxypyridine
- Packaging
- 100mg
- Price
- $74
- Updated
- 2021/12/16
2,6-DICHLORO-4-METHOXY-PYRIDINE Chemical Properties,Usage,Production
Synthesis
67-56-1
16063-69-7
17228-75-0
To a solution of 2,4,6-trichloropyridine (3.64 g, 20.0 mmol) in DMF (20 mL) was slowly added NaH (60% dispersed in mineral oil, 840 mg, 21 mmol) and methanol (673 mg, 21 mmol) at 0 °C. The reaction mixture was stirred at room temperature for 16 hours. Upon completion of the reaction, the mixture was concentrated and partitioned between ethyl acetate (30 mL) and water (15 mL). The organic layer was dried over anhydrous sodium sulfate, filtered and concentrated. The residue was purified by silica gel column chromatography to afford 2,6-dichloro-4-methoxypyridine (3.0 g, yield: 94%) using ethyl acetate (0-5%) in hexane as eluent.
References
[1] Patent: WO2018/106459, 2018, A1. Location in patent: Paragraph 00110
[2] Bioorganic and Medicinal Chemistry, 2017, vol. 25, # 15, p. 3947 - 3963
2,6-DICHLORO-4-METHOXY-PYRIDINE Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from 2,6-DICHLORO-4-METHOXY-PYRIDINE manufacturers
- Product
- 2,6-DICHLORO-4-METHOXY-PYRIDINE 17228-75-0
- Price
- US $9.80/KG
- Min. Order
- 1g
- Purity
- ≥99%
- Supply Ability
- 100kg
- Release date
- 2020-01-08