Uses
ChemicalBook > CAS DataBase List > (2-BROMO-6-FLUOROPHENYL)METHANOL

(2-BROMO-6-FLUOROPHENYL)METHANOL

Uses
Product Name
(2-BROMO-6-FLUOROPHENYL)METHANOL
CAS No.
261723-33-5
Chemical Name
(2-BROMO-6-FLUOROPHENYL)METHANOL
Synonyms
2-Bromo-6-fluorobenzyl alcohol;6-Bromo-2-fluorobenzyl alcohol;2-bromo-6-fluoroBenzenemethanol;(2-BROMO-6-FLUOROPHENYL)METHANOL;BenzeneMethanol, 2-broMo-6-fluoro-
CBNumber
CB62449432
Molecular Formula
C7H6BrFO
Formula Weight
205.02
MOL File
261723-33-5.mol
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(2-BROMO-6-FLUOROPHENYL)METHANOL Property

Melting point:
40-60°
Boiling point:
256.7±25.0 °C(Predicted)
Density 
1.658±0.06 g/cm3(Predicted)
storage temp. 
Sealed in dry,Room Temperature
pka
13.47±0.10(Predicted)
form 
solid
color 
White
InChI
InChI=1S/C7H6BrFO/c8-6-2-1-3-7(9)5(6)4-10/h1-3,10H,4H2
InChIKey
HHGJENWYHVFPSA-UHFFFAOYSA-N
SMILES
C1(CO)=C(F)C=CC=C1Br
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Safety

HS Code 
2906290090
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P405Store locked up.

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N-Bromosuccinimide Price

TRC
Product number
B692105
Product name
2-Bromo-6-fluorobenzylalcohol
Packaging
500mg
Price
$65
Updated
2021/12/16
TRC
Product number
B692105
Product name
2-Bromo-6-fluorobenzylalcohol
Packaging
100mg
Price
$45
Updated
2021/12/16
SynQuest Laboratories
Product number
2701-B-01
Product name
2-Bromo-6-fluorobenzyl alcohol
Packaging
5G
Price
$48
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
HCH0036852
Product name
(2-BROMO-6-FLUOROPHENYL)METHANOL
Purity
95.00%
Packaging
5G
Price
$909.56
Updated
2021/12/16
ChemScene
Product number
CS-W006374
Product name
(2-Bromo-6-fluorophenyl)methanol
Purity
99.86%
Packaging
10g
Price
$67
Updated
2021/12/16
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(2-BROMO-6-FLUOROPHENYL)METHANOL Chemical Properties,Usage,Production

Uses

2-Bromo-6-fluorobenzyl alcohol is an important pharmaceutical intermediate.

Synthesis

360575-28-6

261723-33-5

General procedure for the synthesis of 2-fluoro-6-bromobenzenemethanol from 2-bromo-6-fluorobenzaldehyde: Sodium borohydride (284 g, 7.93 mol) was added batchwise to a solution of 2-bromo-6-fluorobenzaldehyde (1.60 kg, 7.91 mol) in methanol (14 L) at 0 °C, with a controlled rate of addition to regulate exothermic and gas production. After 15 minutes of reaction, the reaction was quenched with water (500 mL) and the reaction mixture was subsequently concentrated to give a yellow oil. The oil was dissolved in ethyl acetate (6L) and washed with (3L) water. The aqueous layer was back-extracted with ethyl acetate (1L). The organic phases were combined, washed with brine (2L), dried over anhydrous sodium sulfate, filtered and concentrated to give 2-fluoro-6-bromobenzenemethanol as an orange oil (1614 g, 100%). The product was characterized by 1H NMR (CDCl3): δ 7.40 (d, 1H), 7.18 (m, 1H), 7.07 (t, 1H), 4.86 (s, 2H).

References

[1] Patent: US2009/163472, 2009, A1. Location in patent: Page/Page column 18
[2] Patent: US2011/65727, 2011, A1. Location in patent: Page/Page column 16
[3] Patent: US2011/65699, 2011, A1. Location in patent: Page/Page column 14
[4] Advanced Synthesis and Catalysis, 2014, vol. 356, # 16, p. 3415 - 3421

(2-BROMO-6-FLUOROPHENYL)METHANOL Preparation Products And Raw materials

Raw materials

Preparation Products

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(2-BROMO-6-FLUOROPHENYL)METHANOL Suppliers

China 82 India 1 Italy 1 United Kingdom 2 United States 5 Global 91
AS WATER CO., LTD.
Tel
+86-18994963526 +8618994963526
Email
1346073549@qq.com
Country
United Kingdom
ProdList
176
Advantage
58
Apollo Scientific Ltd.
Tel
--
Fax
--
Email
sales@apolloscientific.co.uk
Country
United Kingdom
ProdList
6084
Advantage
88
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View Lastest Price from (2-BROMO-6-FLUOROPHENYL)METHANOL manufacturers

Shaanxi Dideu Medichem Co. Ltd
Product
2-Bromo-6-fluorobenzyl alcohol 261723-33-5
Price
US $0.00-0.00/KG
Min. Order
10mg
Purity
99%HPLC
Supply Ability
2000tons
Release date
2020-01-17
Hangzhou ICH Biofarm Co., Ltd
Product
2-Bromo-6-fluorobenzyl alcohol 261723-33-5
Price
US $0.00/kg
Min. Order
1kg
Purity
98%
Supply Ability
2000kg
Release date
2023-06-09
Henan Bao Enluo International TradeCo.，LTD
Product
(2-BROMO-6-FLUOROPHENYL)METHANOL 261723-33-5
Price
US $20.00/kg
Min. Order
1kg
Purity
99.99%
Supply Ability
50000tons
Release date
2023-08-08

261723-33-5, (2-BROMO-6-FLUOROPHENYL)METHANOLRelated Search:

6-BROMO-2,3-DIFLUOROBENZENEMETHANOL 2,4-DIBROMO-6-FLUOROBENZOIC ACID 6-Bromo-2-fluoro-3-methoxy-benzoic acid 2-Bromo-6-fluorobenzoic acid 2-BROMO-6-FLUOROBENZOIC ACID ETHYL ESTER RARECHEM AL BP 1302 6-Bromo-2,3,4-Trifluorobenzoic Acid 2-BROMO-3,4,5,6-TETRAFLUOROBENZYLALCOHOL 2-BROMO-6-FLUOROBENZOIC ACID METHYL ESTER 2,4-DIBROMO-6-FLUOROBENZYL ALCOHOL 2-Bromo-3,4,5,6-tetrafluorobenzoic acid ethyl 2-bromo-6-fluorobenzimidate RARECHEM AL BI 1302 RARECHEM AL BF 1302 (2-BROMO-6-FLUOROPHENYL)METHANOL 2,3-DIFLUORO-6-BROMOBENZOIC ACID

  • 2-bromo-6-fluoroBenzenemethanol
  • (2-BROMO-6-FLUOROPHENYL)METHANOL
  • 6-Bromo-2-fluorobenzyl alcohol
  • 2-Bromo-6-fluorobenzyl alcohol
  • BenzeneMethanol, 2-broMo-6-fluoro-
  • 261723-33-5