1-BROMO-3-CHLORO-2-IODOBENZENE

Product Name: 1-BROMO-3-CHLORO-2-IODOBENZENE
CAS No.: 450412-28-9
Chemical Name: 1-BROMO-3-CHLORO-2-IODOBENZENE
Synonyms: 2-Bromo-6-chloroiodobenzene;1-BROMO-3-CHLORO-2-IODOBENZENE;2-Bromo-6-chloroiodobenzene 99%;1-Bromo-3-chloro-2-Iodobenzenne;Benzene, 1-bromo-3-chloro-2-iodo-;1-Bromo-3-chloro-2-iodobenzene,97%
CBNumber: CB62452476
Molecular Formula: C6H3BrClI
Formula Weight: 317.35
MOL File: 450412-28-9.mol

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1-BROMO-3-CHLORO-2-IODOBENZENE Property

Melting point:: 75-76 °C(Solv: ethanol (64-17-5))
Boiling point:: 285.9±20.0 °C(Predicted)
Density: 2.272±0.06 g/cm3(Predicted)
storage temp.: Keep in dark place,Sealed in dry,Room Temperature
form: Solid
Appearance: Off-white to light brown Solid
Sensitive: Light Sensitive
InChI: InChI=1S/C6H3BrClI/c7-4-2-1-3-5(8)6(4)9/h1-3H
InChIKey: GIMVCZMZRZGDTL-UHFFFAOYSA-N
SMILES: C1(Br)=CC=CC(Cl)=C1I

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Safety

HS Code: 2903998090

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P405Store locked up.

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N-Bromosuccinimide Price

TCI Chemical

Product number: B5765
Product name: 1-Bromo-3-chloro-2-iodobenzene
Packaging: 1G
Price: $45
Updated: 2025/07/31

TCI Chemical

Product number: B5765
Product name: 1-Bromo-3-chloro-2-iodobenzene
Packaging: 5G
Price: $155
Updated: 2025/07/31

TRC

Product number: B415633
Product name: 1-Bromo-3-chloro-2-iodobenzene
Packaging: 100mg
Price: $75
Updated: 2021/12/16

Apolloscientific

Product number: OR400660
Product name: 2-Bromo-6-chloroiodobenzene
Purity: 99%
Packaging: 1g
Price: $15
Updated: 2021/12/16

SynQuest Laboratories

Product number: 1600-W-02
Product name: 2-Bromo-6-chloroiodobenzene
Purity: 99%
Packaging: 1g
Price: $24
Updated: 2021/12/16

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1-BROMO-3-CHLORO-2-IODOBENZENE Chemical Properties,Usage,Production

Synthesis

108-37-2

450412-28-9

Step 1. Synthesis of 1-bromo-3-chloro-2-iodobenzene: To an anhydrous THF (664 mL) solution containing diisopropylamine (76 mL, 0.4 mol) was slowly added dropwise a n-hexane (220 mL) solution of 2.5 M n-butyllithium (n-BuLi, 160 mL, 0.4 mol) at -78 °C for 1 h under nitrogen protection. The reaction temperature was maintained at -78 °C and stirring was continued for 1 h. A solution of 1-bromo-3-chlorobenzene (76 g, 0.4 mol) in anhydrous THF (300 mL) was added slowly dropwise. After the dropwise addition, the reaction was kept at -78 °C for 1 h. Subsequently, a solution of anhydrous THF (400 mL) with iodine (101 g, 0.4 mol) was added slowly dropwise. The reaction system was gradually warmed to room temperature over 2 hours and stirring was continued at room temperature for 18 hours. After completion of the reaction, the mixture was concentrated under reduced pressure to give the crude product (120 g). The crude product was purified by distillation under reduced pressure to give 1-bromo-3-chloro-2-iodobenzene (115 g, 91% yield). The structure of the product was confirmed by 1H NMR (400 MHz, CDCl3) and mass spectrometry (MS): 1H NMR δ 7.12-7.18 (t, 1H), 7.35-7.41 (dd, 1H), 7.49-7.54 (dd, 1H); MS (E/Z): 317 (M+H+).

References

[1] Patent: WO2008/124575, 2008, A1. Location in patent: Page/Page column 103
[2] Patent: US2010/317697, 2010, A1. Location in patent: Page/Page column 47
[3] Patent: WO2008/124582, 2008, A1. Location in patent: Page/Page column 86-87
[4] Patent: WO2007/117560, 2007, A2. Location in patent: Page/Page column 169
[5] Patent: WO2008/124577, 2008, A1. Location in patent: Page/Page column 69

1-BROMO-3-CHLORO-2-IODOBENZENE Preparation Products And Raw materials

Raw materials

Preparation Products

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1-BROMO-3-CHLORO-2-IODOBENZENE Suppliers

Americas 1 China 95 Europe 1 India 5 Japan 1 United Kingdom 1 United States 6 Global 110

Shanghai Wuping Biological Technology Co., Ltd.

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Energy Chemical

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Shanghai Topbiochem Technology Co., Ltd

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TOKYO CHEMICAL INDUSTRY CO., LTD.

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View Lastest Price from 1-BROMO-3-CHLORO-2-IODOBENZENE manufacturers

Career Henan Chemical Co

Product: 1-BROMO-3-CHLORO-2-IODOBENZENE 450412-28-9
Price: US $1.00/g
Min. Order: 1g
Purity: 97%
Supply Ability: 100kg
Release date: 2020-01-09

450412-28-9, 1-BROMO-3-CHLORO-2-IODOBENZENERelated Search:

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1-Bromo-3-chloro-2-Iodobenzenne

2-Bromo-6-chloroiodobenzene 99%

1-BROMO-3-CHLORO-2-IODOBENZENE

Benzene, 1-bromo-3-chloro-2-iodo-

1-Bromo-3-chloro-2-iodobenzene,97%

2-Bromo-6-chloroiodobenzene

450412-28-9