METHYL 3-BROMO-5-(HYDROXYMETHYL)BENZOATE

Product Name: METHYL 3-BROMO-5-(HYDROXYMETHYL)BENZOATE
CAS No.: 307353-32-8
Chemical Name: METHYL 3-BROMO-5-(HYDROXYMETHYL)BENZOATE
Synonyms: METHYL 3-BROMO-5-(HYDROXYMETHYL)BENZOATE;3-Bromo-5-hydroxymethyl-benzoic acid methyl ester;Benzoic acid, 3-bromo-5-(hydroxymethyl)-, methyl ester
CBNumber: CB62455255
Molecular Formula: C9H9BrO3
Formula Weight: 245.07
MOL File: 307353-32-8.mol

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METHYL 3-BROMO-5-(HYDROXYMETHYL)BENZOATE Property

Boiling point:: 354.2±32.0 °C(Predicted)
Density: 1.557±0.06 g/cm3(Predicted)
storage temp.: Sealed in dry,Room Temperature
pka: 14.08±0.10(Predicted)
Appearance: White to off-white Solid
InChI: InChI=1S/C9H9BrO3/c1-13-9(12)7-2-6(5-11)3-8(10)4-7/h2-4,11H,5H2,1H3
InChIKey: PWAJHVDGAMQOPF-UHFFFAOYSA-N
SMILES: C(OC)(=O)C1=CC(CO)=CC(Br)=C1

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Safety

HS Code: 2916399090

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

ChemScene

Product number: CS-B1348
Product name: Methyl3-bromo-5-(hydroxymethyl)benzoate
Purity: 96.56%
Packaging: 250mg
Price: $56
Updated: 2021/12/16

SynQuest Laboratories

Product number: 2629-9-40
Product name: Methyl 3-Bromo-5-(hydroxymethyl)benzoate
Packaging: 250mg
Price: $76
Updated: 2021/12/16

ChemScene

Product number: CS-B1348
Product name: Methyl3-bromo-5-(hydroxymethyl)benzoate
Purity: 96.56%
Packaging: 1g
Price: $155
Updated: 2021/12/16

SynQuest Laboratories

Product number: 2629-9-40
Product name: Methyl 3-Bromo-5-(hydroxymethyl)benzoate
Packaging: 1g
Price: $228
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: HCH0361628
Product name: METHYL-3-BROMO-5-(HYDROXYMETHYL)BENZOATE
Purity: 95.00%
Packaging: 5MG
Price: $503.51
Updated: 2021/12/16

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METHYL 3-BROMO-5-(HYDROXYMETHYL)BENZOATE Chemical Properties,Usage,Production

Synthesis

220286-47-5

307353-32-8

General procedure for the synthesis of methyl 3-bromo-5-(hydroxymethyl)benzoate from methyl 3-amino-5-(hydroxymethyl)benzoate: Methyl 3-amino-5-(hydroxymethyl)benzoate (2.4 g, 13.2 mmol) was dissolved in anhydrous acetonitrile (10 mL) and slowly added dropwise to a solution of acetonitrile (20 mL) containing copper(II) bromide (3.54 g, 15.8 mmol) and tert-butyl nitrite (2.24 mL, 18.9 mmol). (2.24 mL, 18.9 mmol) in acetonitrile (20 mL), and the reaction temperature was maintained at 65 °C. The reaction mixture was stirred at 65 °C. The reaction mixture was stirred at 65 °C for 30 min, then cooled to room temperature and subsequently poured into 1N hydrochloric acid solution and extracted with ether. The organic layers were combined, washed with brine (2 times), dried over anhydrous sodium sulfate and concentrated. Purification by silica gel column chromatography (eluent: 30% ethyl acetate/hexane) afforded the target product methyl 3-bromo-5-(hydroxymethyl)benzoate 2.0 g in 62% yield. The product was identified by 1H-NMR (CDCl3, 300 MHz): δ 8.04 (s, 1H), 7.90 (s, 1H), 7.69 (s, 1H), 4.70 (s, 2H), 3.89 (s, 3H). Mass spectrometry analysis showed a molecular ion peak of 246.98 (MH)+.

References

[1] Patent: US2007/249607, 2007, A1. Location in patent: Page/Page column 85

METHYL 3-BROMO-5-(HYDROXYMETHYL)BENZOATE Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from METHYL 3-BROMO-5-(HYDROXYMETHYL)BENZOATE manufacturers

Qingdao RENAS Polymer Material Co., Ltd.

Product: methyl 3-bromo-5-(hydroxymethyl)benzoate 307353-32-8
Price: US $0.00/kg
Min. Order: 20kg
Purity: 99%
Supply Ability: 20 tons
Release date: 2025-05-12

307353-32-8, METHYL 3-BROMO-5-(HYDROXYMETHYL)BENZOATERelated Search:

5-TERT-BUTYL METHYLISOPHTHALATE METHYL 3-BROMO-5-(HYDROXYMETHYL)BENZOATE 5-BROMO-1,3-DIHYDROXYMETHYLBENZENE DIMETHYL 5-BROMOISOPHTHALATE

METHYL 3-BROMO-5-(HYDROXYMETHYL)BENZOATE

3-Bromo-5-hydroxymethyl-benzoic acid methyl ester

Benzoic acid, 3-bromo-5-(hydroxymethyl)-, methyl ester

307353-32-8