5-TERT-BUTYL METHYLISOPHTHALATE
- Product Name
- 5-TERT-BUTYL METHYLISOPHTHALATE
- CAS No.
- 161796-10-7
- Chemical Name
- 5-TERT-BUTYL METHYLISOPHTHALATE
- Synonyms
- CHEMPACIFIC 41251;3-Bromo-5-(methoxycarbonyl);Methyl 5-broMoisophthalic acid;monomethyl 5-bromoisophthalate;5-TERT-BUTYL METHYLISOPHTHALATE;3-TERT-BUTYL METHYLISOPHTHALATE;5-TERT-BUTYL DIMETHYLISOPHTHALATE;3-BROMO-5-(METHOXYCARBONYL)BENZOIC ACID;METHYL 5-TERT-BUTYL-ISOPHTHALATE DIESTER;5-BROMOISOPHTHALIC ACID MONOMETHYL ESTER
- CBNumber
- CB6121039
- Molecular Formula
- C9H7BrO4
- Formula Weight
- 259.05
- MOL File
- 161796-10-7.mol
5-TERT-BUTYL METHYLISOPHTHALATE Property
- Melting point:
- 191-193 °C
- Boiling point:
- 385.3±32.0 °C(Predicted)
- Density
- 1.660±0.06 g/cm3(Predicted)
- storage temp.
- Sealed in dry,Room Temperature
- pka
- 3.44±0.10(Predicted)
- Appearance
- White to yellow Solid
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H332Harmful if inhaled
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- B696665
- Product name
- 3-Bromo-5-(methoxycarbonyl)benzoicacid
- Packaging
- 50mg
- Price
- $55
- Updated
- 2021/12/16
- Product number
- FB142306
- Product name
- 3-Bromo-5-(methoxycarbonyl)benzoic acid
- Packaging
- 100mg
- Price
- $84
- Updated
- 2021/12/16
- Product number
- J99028
- Product name
- 3-Bromo-5-(methoxycarbonyl)benzoicacid
- Packaging
- 1g
- Price
- $105
- Updated
- 2021/12/16
- Product number
- FB142306
- Product name
- 3-Bromo-5-(methoxycarbonyl)benzoic acid
- Packaging
- 250mg
- Price
- $167.5
- Updated
- 2021/12/16
- Product number
- FB142306
- Product name
- 3-Bromo-5-(methoxycarbonyl)benzoic acid
- Packaging
- 500mg
- Price
- $290
- Updated
- 2021/12/16
5-TERT-BUTYL METHYLISOPHTHALATE Chemical Properties,Usage,Production
Synthesis
28179-47-7
161796-10-7
Step G (2): synthesis of 3-bromo-5-(methoxycarbonyl)benzoic acid. To a mixed solution containing copper(II) bromide (5.5 g, 24.6 mmol), tert-butyl nitrite (3.17 g, 30.75 mmol), and acetonitrile (300 mL) was slowly added a solution of acetonitrile (300 mL) of 3-amino-5-(methoxycarbonyl)benzoic acid (4.0 g, 20.5 mmol) for 30 min at 0 °C. Subsequently, the reaction mixture was warmed to room temperature and stirring was continued for 3 hours. Upon completion of the reaction, water was added and the acetonitrile was removed by distillation under reduced pressure. To the residue, ethyl acetate (600 mL) was added, and the organic layer was washed sequentially with 3N HCl, water, dried with anhydrous Na2SO4, and concentrated under reduced pressure to afford the target product methyl 3-bromo-5-carboxybenzoate in 97% yield. The product was characterized as follows: 1H NMR (CDCl3, 500 MHz) δ 3.96 (3H, s), 8.41 (1H, s), 8.67 (1H, s); MS (ESI) m/z 259.02 (M-H)-.
References
[1] Patent: WO2006/99352, 2006, A1. Location in patent: Page/Page column 41
[2] Journal of the American Chemical Society, 2003, vol. 125, # 34, p. 10241 - 10249
[3] Patent: WO2009/15166, 2009, A1. Location in patent: Page/Page column 87-88
[4] Bioorganic and Medicinal Chemistry Letters, 2009, vol. 19, # 10, p. 2654 - 2660
[5] Patent: US2006/223759, 2006, A1. Location in patent: Page/Page column 193
5-TERT-BUTYL METHYLISOPHTHALATE Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from 5-TERT-BUTYL METHYLISOPHTHALATE manufacturers
- Product
- 3-Bromo-5-(methoxycarbonyl)benzoic acid 161796-10-7
- Price
- US $0.00/KG
- Min. Order
- 1KG
- Purity
- 97.8%
- Supply Ability
- 100 tons
- Release date
- 2022-02-08
- Product
- 5-TERT-BUTYL METHYLISOPHTHALATE 161796-10-7
- Price
- US $1.00/KG
- Min. Order
- 1KG
- Purity
- 98%
- Supply Ability
- 150KG
- Release date
- 2019-07-09