3-BROMO-5-HYDROXYBENZOIC ACID

Product Name: 3-BROMO-5-HYDROXYBENZOIC ACID
CAS No.: 140472-69-1
Chemical Name: 3-BROMO-5-HYDROXYBENZOIC ACID
Synonyms: 3-BROMO-5-HYDROXYBENZOIC ACID;5-Hydroxy-3-bromobenzoic acid;Benzoic acid, 3-broMo-5-hydroxy-;3-BroMo-5-hydroxybenzoic acid 97%;3-BroMo-5-hydroxybenzoic acid
CBNumber: CB1972245
Molecular Formula: C7H5BrO3
Formula Weight: 217.02
MOL File: 140472-69-1.mol

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3-BROMO-5-HYDROXYBENZOIC ACID Property

Melting point:: 237-241 °C
Boiling point:: 388.1±32.0 °C(Predicted)
Density: 1.861±0.06 g/cm3(Predicted)
storage temp.: Sealed in dry,Room Temperature
solubility: soluble in Methanol
form: powder to crystal
pka: 3.69±0.10(Predicted)
color: White to Light yellow to Light orange
InChI: InChI=1S/C7H5BrO3/c8-5-1-4(7(10)11)2-6(9)3-5/h1-3,9H,(H,10,11)
InChIKey: WGIBEMRBLBGETQ-UHFFFAOYSA-N
SMILES: C(O)(=O)C1=CC(O)=CC(Br)=C1
CAS DataBase Reference: 140472-69-1

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Safety

Hazard Codes: Xn,N
Risk Statements: 22-50
Safety Statements: 61
RIDADR: UN 2811 6.1/PG 3
WGK Germany: 3
HazardClass: 9
PackingGroup: III
HS Code: 2918290090
Storage Class: 6.1C - Combustible acute toxic Cat.3
toxic compounds or compounds which causing chronic effects
Hazard Classifications: Acute Tox. 3 Oral
Aquatic Acute 1

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Danger

Hazard statements

H301Toxic if swalloed

H400Very toxic to aquatic life

Precautionary statements

P273Avoid release to the environment.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 686417
Product name: 3-Bromo-5-hydroxybenzoic acid
Purity: 97%
Packaging: 5g
Price: $68.7
Updated: 2025/07/31

TCI Chemical

Product number: B4740
Product name: 3-Bromo-5-hydroxybenzoic Acid
Purity: >98.0%(GC)(T)
Packaging: 1g
Price: $49
Updated: 2025/07/31

TCI Chemical

Product number: B4740
Product name: 3-Bromo-5-hydroxybenzoic Acid
Purity: >98.0%(GC)(T)
Packaging: 5g
Price: $146
Updated: 2025/07/31

TRC

Product number: B699128
Product name: 3-Bromo-5-hydroxybenzoic acid
Packaging: 250mg
Price: $55
Updated: 2021/12/16

TRC

Product number: B699128
Product name: 3-Bromo-5-hydroxybenzoic acid
Packaging: 500mg
Price: $65
Updated: 2021/12/16

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3-BROMO-5-HYDROXYBENZOIC ACID Chemical Properties,Usage,Production

Uses

3-Bromo-5-hydroxybenzoic acid is a carboxylic acid derivative and is used in organic synthesis.

Synthesis Reference(s)

[1] Leukotriene b4 inhibitors. Patent no. US20100240678A1

Synthesis

To a solution of NaOH (12.2 g; 305.8 mmol) in 300 mL of water was added 3-bromo-5-iodo-benzoic acid (20 g, 61.2 mmol) and Cu2O (866 mg, 6.1 mmol). The reaction mixture was heated at 100° C. for 24 h. After complete consumption of the starting material, the reaction mixture was cooled to room temperature and filtered through celite. The filtrate was then acidified with 10% aq. HCl and extracted into ethyl acetate. The organic extract was dried over anhydrous sodium sulfate and concentrated under reduced pressure to afford the 3-Bromo-5-hydroxybenzoic acid as a tan solid (12.3 g, 93% yield).

Purification Methods

The acid crystallises from H2O (m 238-239o), and with Me2SO4 it yields the 3-methoxy derivative with m 190-191o (from EtOH). [Baddar et al. J Chem Soc 469 1955, Beilstein 10 IV 333.]

References

[1] Patent: US2010/240678, 2010, A1. Location in patent: Page/Page column 22
[2] Patent: WO2009/77385, 2009, A1. Location in patent: Page/Page column 63
[3] Patent: WO2005/113494, 2005, A2. Location in patent: Page/Page column 118-119

3-BROMO-5-HYDROXYBENZOIC ACID Preparation Products And Raw materials

Raw materials

Preparation Products

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3-BROMO-5-HYDROXYBENZOIC ACID Suppliers

Americas 1 Belgium 1 China 133 Europe 1 Germany 1 India 25 Japan 3 Switzerland 1 United Kingdom 6 United States 22 Global 194

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View Lastest Price from 3-BROMO-5-HYDROXYBENZOIC ACID manufacturers

Henan Aochuang Chemical Co.,Ltd.

Product: 3-BROMO-5-HYDROXYBENZOIC ACID 140472-69-1
Price: US $0.00-0.00/KG
Min. Order: 1KG
Purity: 98%
Supply Ability: 1ton
Release date: 2022-09-22

Shaanxi Dideu New Materials Co. Ltd

Product: 3-BROMO-5-HYDROXYBENZOIC ACID 140472-69-1
Price: US $0.00-0.00/KG
Min. Order: 1KG
Purity: 98.0%
Supply Ability: 10000KGS
Release date: 2025-02-27

Hebei Chuanghai Biotechnology Co,.LTD

Product: 3-BROMO-5-HYDROXYBENZOIC ACID 140472-69-1
Price: US $9.00/KG
Min. Order: 1KG
Purity: 99.9
Supply Ability: 1 ton
Release date: 2024-08-20

140472-69-1, 3-BROMO-5-HYDROXYBENZOIC ACIDRelated Search:

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Benzoic acid, 3-broMo-5-hydroxy-

5-Hydroxy-3-bromobenzoic acid

3-<WBR>BroMo-<WBR>5-<WBR>hydroxybenzoic acid

3-BroMo-5-hydroxybenzoic acid 97%

3-BROMO-5-HYDROXYBENZOIC ACID

140472-69-1

C7

Carbonyl Compounds

Carboxylic Acids