3-BROMO-5-HYDROXYBENZOIC ACID
- Product Name
- 3-BROMO-5-HYDROXYBENZOIC ACID
- CAS No.
- 140472-69-1
- Chemical Name
- 3-BROMO-5-HYDROXYBENZOIC ACID
- Synonyms
- 3-BROMO-5-HYDROXYBENZOIC ACID;5-Hydroxy-3-bromobenzoic acid;Benzoic acid, 3-broMo-5-hydroxy-;3-BroMo-5-hydroxybenzoic acid 97%;3-
BroMo- 5- hydroxybenzoic acid - CBNumber
- CB1972245
- Molecular Formula
- C7H5BrO3
- Formula Weight
- 217.02
- MOL File
- 140472-69-1.mol
3-BROMO-5-HYDROXYBENZOIC ACID Property
- Melting point:
- 237-241 °C
- Boiling point:
- 388.1±32.0 °C(Predicted)
- Density
- 1.861±0.06 g/cm3(Predicted)
- storage temp.
- Sealed in dry,Room Temperature
- solubility
- soluble in Methanol
- form
- powder to crystal
- pka
- 3.69±0.10(Predicted)
- color
- White to Light yellow to Light orange
- InChI
- InChI=1S/C7H5BrO3/c8-5-1-4(7(10)11)2-6(9)3-5/h1-3,9H,(H,10,11)
- InChIKey
- WGIBEMRBLBGETQ-UHFFFAOYSA-N
- SMILES
- C(O)(=O)C1=CC(O)=CC(Br)=C1
- CAS DataBase Reference
- 140472-69-1
N-Bromosuccinimide Price
- Product number
- 686417
- Product name
- 3-Bromo-5-hydroxybenzoic acid
- Purity
- 97%
- Packaging
- 5g
- Price
- $68.7
- Updated
- 2025/07/31
- Product number
- B4740
- Product name
- 3-Bromo-5-hydroxybenzoic Acid
- Purity
- >98.0%(GC)(T)
- Packaging
- 1g
- Price
- $49
- Updated
- 2025/07/31
- Product number
- B4740
- Product name
- 3-Bromo-5-hydroxybenzoic Acid
- Purity
- >98.0%(GC)(T)
- Packaging
- 5g
- Price
- $146
- Updated
- 2025/07/31
- Product number
- B699128
- Product name
- 3-Bromo-5-hydroxybenzoic acid
- Packaging
- 250mg
- Price
- $55
- Updated
- 2021/12/16
- Product number
- B699128
- Product name
- 3-Bromo-5-hydroxybenzoic acid
- Packaging
- 500mg
- Price
- $65
- Updated
- 2021/12/16
3-BROMO-5-HYDROXYBENZOIC ACID Chemical Properties,Usage,Production
Uses
3-Bromo-5-hydroxybenzoic acid is a carboxylic acid derivative and is used in organic synthesis.
Synthesis Reference(s)
[1] Leukotriene b4 inhibitors. Patent no. US20100240678A1
Synthesis
To a solution of NaOH (12.2 g; 305.8 mmol) in 300 mL of water was added 3-bromo-5-iodo-benzoic acid (20 g, 61.2 mmol) and Cu2O (866 mg, 6.1 mmol). The reaction mixture was heated at 100° C. for 24 h. After complete consumption of the starting material, the reaction mixture was cooled to room temperature and filtered through celite. The filtrate was then acidified with 10% aq. HCl and extracted into ethyl acetate. The organic extract was dried over anhydrous sodium sulfate and concentrated under reduced pressure to afford the 3-Bromo-5-hydroxybenzoic acid as a tan solid (12.3 g, 93% yield).
Purification Methods
The acid crystallises from H2O (m 238-239o), and with Me2SO4 it yields the 3-methoxy derivative with m 190-191o (from EtOH). [Baddar et al. J Chem Soc 469 1955, Beilstein 10 IV 333.]
References
[1] Patent: US2010/240678, 2010, A1. Location in patent: Page/Page column 22
[2] Patent: WO2009/77385, 2009, A1. Location in patent: Page/Page column 63
[3] Patent: WO2005/113494, 2005, A2. Location in patent: Page/Page column 118-119
3-BROMO-5-HYDROXYBENZOIC ACID Preparation Products And Raw materials
Raw materials
Preparation Products
3-BROMO-5-HYDROXYBENZOIC ACID Suppliers
- Tel
- 800-4238616
- Fax
- +1-888-520-1075 / +1-503-283-1987
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- Country
- Americas
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- Advantage
- 75
View Lastest Price from 3-BROMO-5-HYDROXYBENZOIC ACID manufacturers
- Product
- 3-BROMO-5-HYDROXYBENZOIC ACID 140472-69-1
- Price
- US $0.00-0.00/KG
- Min. Order
- 1KG
- Purity
- 98%
- Supply Ability
- 1ton
- Release date
- 2022-09-22
- Product
- 3-BROMO-5-HYDROXYBENZOIC ACID 140472-69-1
- Price
- US $0.00-0.00/KG
- Min. Order
- 1KG
- Purity
- 98.0%
- Supply Ability
- 10000KGS
- Release date
- 2025-02-27
- Product
- 3-BROMO-5-HYDROXYBENZOIC ACID 140472-69-1
- Price
- US $9.00/KG
- Min. Order
- 1KG
- Purity
- 99.9
- Supply Ability
- 1 ton
- Release date
- 2024-08-20