7-Nitro-1,2,3,4-tetrahydroquinoline
- Product Name
- 7-Nitro-1,2,3,4-tetrahydroquinoline
- CAS No.
- 30450-62-5
- Chemical Name
- 7-Nitro-1,2,3,4-tetrahydroquinoline
- Synonyms
- 7-Nitro-1;7-Nitro-1,2,3,4-Terahydroquinoline;7-NITRO-1,2,3,4-TETRAHYDROQUINOLINE;1,2,3,4-TETRAHYDRO-7-NITROQUINOLINE;7-Nitro-1,2,3,4-tetrahydroquinoline>Quinoline, 1,2,3,4-tetrahydro-7-nitro-;7-Nitro-1,2,3,4-tetrahydroquinoline,95%;7-NITRO-1,2,3,4-TETRAHYDRO-QUINOLINE HYDROCHLORIDE;7-Nitro-1,2,3,4-tetrahydroquinoline 1,2,3,4-Tetrahydro-7-nitroquinoline
- CBNumber
- CB6246251
- Molecular Formula
- C9H10N2O2
- Formula Weight
- 178.19
- MOL File
- 30450-62-5.mol
7-Nitro-1,2,3,4-tetrahydroquinoline Property
- Melting point:
- 61.0 to 65.0 °C
- Boiling point:
- 325.2±31.0 °C(Predicted)
- Density
- 1.236±0.06 g/cm3(Predicted)
- storage temp.
- Keep in dark place,Sealed in dry,Room Temperature
- solubility
- soluble in Methanol
- pka
- 3.44±0.20(Predicted)
- form
- Powder
- color
- Red
- InChI
- InChI=1S/C9H10N2O2/c12-11(13)8-4-3-7-2-1-5-10-9(7)6-8/h3-4,6,10H,1-2,5H2
- InChIKey
- WSWMGHRLUYADNA-UHFFFAOYSA-N
- SMILES
- N1C2=C(C=CC([N+]([O-])=O)=C2)CCC1
- CAS DataBase Reference
- 30450-62-5(CAS DataBase Reference)
N-Bromosuccinimide Price
- Product number
- MNO000018
- Product name
- 7-Nitro-1,2,3,4-tetrahydroquinoline
- Purity
- Aldrich
- Packaging
- 1g
- Price
- $73.1
- Updated
- 2025/07/31
- Product number
- N0955
- Product name
- 7-Nitro-1,2,3,4-tetrahydroquinoline
- Purity
- >98.0%(GC)(T)
- Packaging
- 5g
- Price
- $69
- Updated
- 2025/07/31
- Product number
- N0955
- Product name
- 7-Nitro-1,2,3,4-tetrahydroquinoline
- Purity
- >98.0%(GC)(T)
- Packaging
- 25g
- Price
- $224
- Updated
- 2025/07/31
- Product number
- N497115
- Product name
- 7-Nitro-1,2,3,4-tetrahydroquinoline
- Packaging
- 10mg
- Price
- $45
- Updated
- 2021/12/16
- Product number
- N497115
- Product name
- 7-Nitro-1,2,3,4-tetrahydroquinoline
- Packaging
- 50mg
- Price
- $60
- Updated
- 2021/12/16
7-Nitro-1,2,3,4-tetrahydroquinoline Chemical Properties,Usage,Production
Uses
7-Nitro-1,2,3,4-tetrahydroquinoline is a quinoline compound that can be used as a reagent in chemical reactions or as an intermediate in organic synthesis. It can be used to prepare 7-Aminoquinoline and 7-Nitroquinoline.
Synthesis
7-Nitro-1,2,3,4-tetrahydroquinoline is synthesised by the reaction of 1,2,3,4-tetrahydroquinoline and nitric acid in sulphuric acid solution. The specific synthesis steps are as follows:
Concentrated sulfuric acid (30.00 mL) was cooled to -10° C. with an ice/salt bath.
To this, 1,2,3,4-tetrahydro-quinoline (10.60 g, 75.60 mmol) and a solution of nitric acid (99.5percent, 4.80 g, 75.60 mmol) in sulfuric acid (15.00 mL) were added simultaneously within 1 hour, so that the temperature of the reaction mixture does not exceed 10° C.
The mixture was stirred then for 2.5 hours at -5° C., then poured over ice and treated with sodium carbonate (0.10 kg) until pH 8-9 was reached.
The solid was filtered, washing with water, then dissolved in dichloromethane.
The organic phase was washed with water, dried over magnesium sulphate and evaporated.
7-Nitro-1,2,3,4-tetrahydro-quinoline was obtained as a viscous brown oil, 13.70 g (85percent), 84percent purity.
References
[1] Patent: US2008/153805, 2008, A1. Location in patent: Page/Page column 15
[2] Patent: US9512111, 2016, B2. Location in patent: Page/Page column 93; 94
[3] Patent: US9522908, 2016, B2. Location in patent: Page/Page column 55; 58; 59
[4] Chemistry - A European Journal, 2008, vol. 14, # 6, p. 1784 - 1792
[5] European Journal of Organic Chemistry, 2010, # 19, p. 3593 - 3610
7-Nitro-1,2,3,4-tetrahydroquinoline Preparation Products And Raw materials
Raw materials
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View Lastest Price from 7-Nitro-1,2,3,4-tetrahydroquinoline manufacturers
- Product
- 7-Nitro-1,2,3,4-tetrahydroquinoline 30450-62-5
- Price
- US $0.00/G
- Min. Order
- 10G
- Purity
- 98%min
- Supply Ability
- 300KG/month
- Release date
- 2023-01-10
- Product
- 1,2,3,4-TETRAHYDRO-7-NITROQUINOLINE 30450-62-5
- Price
- US $1.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 100KG
- Release date
- 2019-12-25