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GGSTOPTM

Product Name
GGSTOPTM
CAS No.
926281-37-0
Chemical Name
GGSTOPTM
Synonyms
GGsTop;GGSTOPTM;GGsTop(R);GGsTop (Nahlsgen);GGsTop (Synonyms: Nahlsgen);3-[[(3-Amino-3-carboxypropyl)methoxyphosphinyl]oxy]benzeneacetic acid;2-Amino-4-((3-(carboxymethyl)phenoxy)(methoxy)phosphoryl)butanoic acid;Benzeneacetic acid, 3-[[(3-amino-3-carboxypropyl)methoxyphosphinyl]oxy]-
CBNumber
CB62467186
Molecular Formula
C13H18NO7P
Formula Weight
331.26
MOL File
926281-37-0.mol
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GGSTOPTM Property

Boiling point:
557.7±50.0 °C(Predicted)
Density 
1.403±0.06 g/cm3(Predicted)
storage temp. 
Store at -20°C
solubility 
<33.13mg/ml in H2O; <33.13mg/ml in DMSO
form 
solid
pka
2.18±0.10(Predicted)
color 
White
Cosmetics Ingredients Functions
ANTIOXIDANT
SKIN CONDITIONING
HUMECTANT
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P337+P313IF eye irritation persists: Get medical advice/attention.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Tocris
Product number
4452
Product name
GGsTop
Purity
≥95%(HPLC)
Packaging
10
Price
$235
Updated
2021/12/16
TRC
Product number
N497063
Product name
Nahlsgen
Packaging
10mg
Price
$160
Updated
2021/12/16
Usbiological
Product number
255372
Product name
GGsTop
Packaging
10mg
Price
$522
Updated
2021/12/16
ApexBio Technology
Product number
B5602
Product name
GGsTop
Packaging
10mg
Price
$345
Updated
2021/12/16
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GGSTOPTM Chemical Properties,Usage,Production

Uses

Nahlsgen is a highly selective, and irreversible γ-glutamyl transpeptidase (GGT) inhibitor with no inhibitory activity on glutamine amidotransferases.

in vivo

GGsTop (1 mg/kg) lowers levels of ALT, AST, γ-GT at 12, 24, and 48 h after ischemia-reperfusion in rats[3].
GGsTop also reduces 4-HNE and TNF-α production, and decreases hepatic necrosis in rats[3].

Animal Model:Male rats (9 week old)[3]
Dosage:1 mg/kg
Administration:Injected into the inferior vena cava for 12, 24, 48 h
Result:Lowered the serum levels of ALT, AST, prevented the increase of serum γ-GT levels in IR-GGsTop group.

storage

Store at -20°C

GGSTOPTM Preparation Products And Raw materials

Raw materials

Preparation Products

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GGSTOPTM Suppliers

Beijing HwrkChemical Technology Co., Ltd
Tel
89508211 18501085097
Fax
010-89508210
Email
sales.bj@hwrkchemical.com
Country
China
ProdList
9416
Advantage
55
Nanjing Chemlin Chemical Co., Ltd
Tel
025-83697070 13770331960
Fax
+86-25-83453306
Email
info@chemlin.com.cn
Country
China
ProdList
15984
Advantage
64
Shanghai Aladdin Bio-Chem Technology Co.,LTD
Tel
400-6206333 13167063860
Fax
021-50323701
Email
anhua.mao@aladdin-e.com
Country
China
ProdList
26312
Advantage
65
MedChemexpress LLC
Tel
021-58955995
Fax
609-228-5909
Email
sales@medchemexpress.cn
Country
United States
ProdList
4861
Advantage
58
Nanjing Dulai Biotechnology Co., Ltd.
Tel
025-84699383-8003;025-846993838003-8003 18013301593;18013301590
Fax
025-84699383-8003
Email
njduly@126.com
Country
China
ProdList
3293
Advantage
55
Bide Pharmatech Ltd.
Tel
400-400-164-7117 18317119277
Fax
+86-21-61629029
Email
product02@bidepharm.com
Country
China
ProdList
40000
Advantage
60
Zhengzhou Alfachem Co., Ltd.
Tel
0371-53765687 18937137882
Fax
QQ:2885373884
Email
3969243885@qq.com
Country
China
ProdList
7810
Advantage
55
Shanghai YuanYe Biotechnology Co., Ltd.
Tel
021-61312847; 18021002903
Fax
QQ:3008007432
Email
3008007409@qq.com
Country
China
ProdList
71615
Advantage
60
Jinan Yaoyan Pharmaceutical Co., Ltd.
Tel
Fax
-
Email
jnyaoyan@163.com
Country
China
ProdList
3069
Advantage
58
Taizhou Crene Biotechnology Co. Ltd.
Tel
+86-0576-88813233 +86-13396860566
Email
sales@pharm-intermediates.com
Country
China
ProdList
1982
Advantage
58

926281-37-0, GGSTOPTMRelated Search:


  • GGSTOPTM
  • 3-[[(3-Amino-3-carboxypropyl)methoxyphosphinyl]oxy]benzeneacetic acid
  • GGsTop
  • GGsTop (Nahlsgen)
  • GGsTop (Synonyms: Nahlsgen)
  • Benzeneacetic acid, 3-[[(3-amino-3-carboxypropyl)methoxyphosphinyl]oxy]-
  • 2-Amino-4-((3-(carboxymethyl)phenoxy)(methoxy)phosphoryl)butanoic acid
  • GGsTop(R)
  • 926281-37-0