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GGSTOPTM

Product Name
GGSTOPTM
CAS No.
926281-37-0
Chemical Name
GGSTOPTM
Synonyms
GGsTop;GGSTOPTM;GGsTop(R);GGsTop (Nahlsgen);GGsTop (Synonyms: Nahlsgen);3-[[(3-Amino-3-carboxypropyl)methoxyphosphinyl]oxy]benzeneacetic acid;2-Amino-4-((3-(carboxymethyl)phenoxy)(methoxy)phosphoryl)butanoic acid;Benzeneacetic acid, 3-[[(3-amino-3-carboxypropyl)methoxyphosphinyl]oxy]-
CBNumber
CB62467186
Molecular Formula
C13H18NO7P
Formula Weight
331.26
MOL File
926281-37-0.mol
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GGSTOPTM Property

Boiling point:
557.7±50.0 °C(Predicted)
Density 
1.403±0.06 g/cm3(Predicted)
storage temp. 
Store at -20°C
solubility 
<33.13mg/ml in H2O; <33.13mg/ml in DMSO
form 
solid
pka
2.18±0.10(Predicted)
color 
White
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Tocris
Product number
4452
Product name
GGsTop
Purity
≥95%(HPLC)
Packaging
10
Price
$235
Updated
2021/12/16
TRC
Product number
N497063
Product name
Nahlsgen
Packaging
10mg
Price
$160
Updated
2021/12/16
Usbiological
Product number
255372
Product name
GGsTop
Packaging
10mg
Price
$522
Updated
2021/12/16
ApexBio Technology
Product number
B5602
Product name
GGsTop
Packaging
10mg
Price
$345
Updated
2021/12/16
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GGSTOPTM Chemical Properties,Usage,Production

Uses

Nahlsgen is a highly selective, and irreversible γ-?glutamyl transpeptidase (GGT) inhibitor with no inhibitory activity on glutamine amidotransferases.

in vivo

GGsTop (1 mg/kg) lowers levels of ALT, AST, γ-GT at 12, 24, and 48 h after ischemia-reperfusion in rats[3].
GGsTop also reduces 4-HNE and TNF-α production, and decreases hepatic necrosis in rats[3].

Animal Model:Male rats (9 week old)[3]
Dosage:1 mg/kg
Administration:Injected into the inferior vena cava for 12, 24, 48 h
Result:Lowered the serum levels of ALT, AST, prevented the increase of serum γ-GT levels in IR-GGsTop group.

storage

Store at -20°C

GGSTOPTM Preparation Products And Raw materials

Raw materials

Preparation Products

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GGSTOPTM Suppliers

Shenzhen Fulkare Biotechnology Co., Ltd.
Tel
15953196022
Email
fulkare@163.com
Country
China
ProdList
94
Advantage
58
Beijing HwrkChemical Technology Co., Ltd
Tel
18515581800 18501085097
Fax
010-89508210
Email
sales.bj@hwrkchemical.com
Country
China
ProdList
9400
Advantage
55
Nanjing Chemlin Chemical Co., Ltd
Tel
025-83697070
Fax
+86-25-83453306
Email
info@chemlin.com.cn
Country
China
ProdList
15883
Advantage
64
Shanghai Aladdin Bio-Chem Technology Co.,LTD
Tel
400-6206333 13167063860
Fax
021-50323701
Email
anhua.mao@aladdin-e.com
Country
China
ProdList
25003
Advantage
65
MedChemexpress LLC
Tel
021-58955995
Fax
609-228-5909
Email
sales@medchemexpress.cn
Country
United States
ProdList
4861
Advantage
58
Nanjing Dulai Biotechnology Co., Ltd.
Tel
025-846993838003-8003 18013301590
Fax
025-84699383-8003
Email
njduly@126.com
Country
China
ProdList
3249
Advantage
55
Zhengzhou Alfachem Co., Ltd.
Tel
0371-53765687 18937137882
Fax
QQ:2885373884
Email
2853979813@qq.com
Country
China
ProdList
7992
Advantage
55
Shanghai YuanYe Biotechnology Co., Ltd.
Tel
021-61312847; 18021002903
Fax
QQ:3008007432
Email
3008007409@qq.com
Country
China
ProdList
71826
Advantage
60
Jinan Yaoyan Pharmaceutical Co., Ltd.
Tel
Fax
-
Email
jnyaoyan@163.com
Country
China
ProdList
3069
Advantage
58
Taizhou Crene Biotechnology Co. Ltd.
Tel
+86-0576-88813233 +86-13396860566
Email
sales@pharm-intermediates.com
Country
China
ProdList
1991
Advantage
58

926281-37-0, GGSTOPTMRelated Search:


  • GGSTOPTM
  • 3-[[(3-Amino-3-carboxypropyl)methoxyphosphinyl]oxy]benzeneacetic acid
  • GGsTop
  • GGsTop (Nahlsgen)
  • GGsTop (Synonyms: Nahlsgen)
  • Benzeneacetic acid, 3-[[(3-amino-3-carboxypropyl)methoxyphosphinyl]oxy]-
  • 2-Amino-4-((3-(carboxymethyl)phenoxy)(methoxy)phosphoryl)butanoic acid
  • GGsTop(R)
  • 926281-37-0