ChemicalBook > CAS DataBase List > 2(1H)-QUINAZOLINONE, 1-(1-METHYLETHYL)-4-[4-(1-METHYLETHYL)PHENYL]-6-(2-PROPYN-1-YLOXY)-

2(1H)-QUINAZOLINONE, 1-(1-METHYLETHYL)-4-[4-(1-METHYLETHYL)PHENYL]-6-(2-PROPYN-1-YLOXY)-

Product Name
2(1H)-QUINAZOLINONE, 1-(1-METHYLETHYL)-4-[4-(1-METHYLETHYL)PHENYL]-6-(2-PROPYN-1-YLOXY)-
CAS No.
478963-79-0
Chemical Name
2(1H)-QUINAZOLINONE, 1-(1-METHYLETHYL)-4-[4-(1-METHYLETHYL)PHENYL]-6-(2-PROPYN-1-YLOXY)-
Synonyms
CaSR-IN-10a;Calcium-sensing receptor antagonist 1;CalciuM-Sensing Receptor Antagonists I;1-(1-methylethyl)-4-[4-(1-methylethyl)phenyl]-6-(2-propyn-1-yloxy)-;CalciumSensing Receptor Antagonists I,Calcium Sensing Receptor Antagonists I;1-(1-Methylethyl)-4-[4-(1-methylethyl)phenyl]-6-(2-propyn-1-yloxy)-2(1H)-Quinazolinone;2(1H)-QUINAZOLINONE, 1-(1-METHYLETHYL)-4-[4-(1-METHYLETHYL)PHENYL]-6-(2-PROPYN-1-YLOXY)-
CBNumber
CB62468567
Molecular Formula
C23H24N2O2
Formula Weight
360.45
MOL File
478963-79-0.mol
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2(1H)-QUINAZOLINONE, 1-(1-METHYLETHYL)-4-[4-(1-METHYLETHYL)PHENYL]-6-(2-PROPYN-1-YLOXY)- Property

Boiling point:
510.1±60.0 °C(Predicted)
Density 
1.08±0.1 g/cm3(Predicted)
storage temp. 
Store at -20°C
solubility 
Soluble in DMSO
pka
0.50±0.20(Predicted)
form 
Powder
color 
Light yellow to yellow
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

ChemScene
Product number
CS-0307
Product name
Calcium-SensingReceptorAntagonistsI
Purity
99.91%
Packaging
10mg
Price
$200
Updated
2021/12/16
ApexBio Technology
Product number
A3275
Product name
Calcium-SensingReceptorAntagonistsI
Packaging
10mg
Price
$376
Updated
2021/12/16
ChemScene
Product number
CS-0307
Product name
Calcium-SensingReceptorAntagonistsI
Purity
99.91%
Packaging
50mg
Price
$550
Updated
2021/12/16
ChemScene
Product number
CS-0307
Product name
Calcium-SensingReceptorAntagonistsI
Purity
99.91%
Packaging
100mg
Price
$850
Updated
2021/12/16
ApexBio Technology
Product number
A3275
Product name
Calcium-SensingReceptorAntagonistsI
Packaging
100mg
Price
$1475
Updated
2021/12/16
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2(1H)-QUINAZOLINONE, 1-(1-METHYLETHYL)-4-[4-(1-METHYLETHYL)PHENYL]-6-(2-PROPYN-1-YLOXY)- Chemical Properties,Usage,Production

Uses

Calcium-Sensing receptor antagonist I is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

References

[1] Widler, Leo et al. 1-Alkyl-4-phenyl-6-alkoxy-1H-quinazolin-2-ones: A Novel Series of Potent Calcium-Sensing Receptor Antagonists.Journal of Medicinal Chemistry(2010),53(5), 2250-2263.

2(1H)-QUINAZOLINONE, 1-(1-METHYLETHYL)-4-[4-(1-METHYLETHYL)PHENYL]-6-(2-PROPYN-1-YLOXY)- Preparation Products And Raw materials

Raw materials

Preparation Products

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2(1H)-QUINAZOLINONE, 1-(1-METHYLETHYL)-4-[4-(1-METHYLETHYL)PHENYL]-6-(2-PROPYN-1-YLOXY)- Suppliers

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478963-79-0, 2(1H)-QUINAZOLINONE, 1-(1-METHYLETHYL)-4-[4-(1-METHYLETHYL)PHENYL]-6-(2-PROPYN-1-YLOXY)-Related Search:


  • 2(1H)-QUINAZOLINONE, 1-(1-METHYLETHYL)-4-[4-(1-METHYLETHYL)PHENYL]-6-(2-PROPYN-1-YLOXY)-
  • CalciuM-Sensing Receptor Antagonists I
  • 1-(1-Methylethyl)-4-[4-(1-methylethyl)phenyl]-6-(2-propyn-1-yloxy)-2(1H)-Quinazolinone
  • Calcium-sensing receptor antagonist 1
  • 1-(1-methylethyl)-4-[4-(1-methylethyl)phenyl]-6-(2-propyn-1-yloxy)-
  • CaSR-IN-10a
  • CalciumSensing Receptor Antagonists I,Calcium Sensing Receptor Antagonists I
  • 478963-79-0