4-bromo-1H-pyrrolo[2,3-c]pyridine
- Product Name
- 4-bromo-1H-pyrrolo[2,3-c]pyridine
- CAS No.
- 69872-17-9
- Chemical Name
- 4-bromo-1H-pyrrolo[2,3-c]pyridine
- Synonyms
- 4-BroM-6-azaindol;4-Bromo-6-azaindole;4-Bromo-6-azaindole 97%;4-broMo-1H-pyrrolo[2,3-c]pyridin;4-bromo-1H-pyrrolo[2,3-c]pyridine;1H-PYRROLO[2,3-C]-PYRIDINE,4-BROMO-;4-Bromo-1H-pyrrolo[2,3-c]pyridine (69872-17-9)
- CBNumber
- CB62484383
- Molecular Formula
- C7H5BrN2
- Formula Weight
- 197.03
- MOL File
- 69872-17-9.mol
4-bromo-1H-pyrrolo[2,3-c]pyridine Property
- Melting point:
- 188-189℃
- Boiling point:
- 337.6±22.0 °C(Predicted)
- Density
- 1.770
- storage temp.
- 2-8°C(protect from light)
- pka
- 13.73±0.40(Predicted)
- form
- solid
- color
- White to light brown
- InChI
- InChI=1S/C7H5BrN2/c8-6-3-9-4-7-5(6)1-2-10-7/h1-4,10H
- InChIKey
- NZUWATDXQMWXMY-UHFFFAOYSA-N
- SMILES
- C1=NC=C(Br)C2C=CNC1=2
Safety
- RIDADR
- UN2811
- HazardClass
- IRRITANT
- HS Code
- 2933998090
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P260Do not breathe dust/fume/gas/mist/vapours/spray.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
N-Bromosuccinimide Price
- Product number
- B687173
- Product name
- 4-Bromo-1H-pyrrolo[2,3-c]pyridine
- Packaging
- 250mg
- Price
- $75
- Updated
- 2021/12/16
- Product number
- OR55212
- Product name
- 4-Bromo-6-azaindole
- Purity
- 97%
- Packaging
- 1g
- Price
- $63
- Updated
- 2021/12/16
- Product number
- 3H32-9-89
- Product name
- 4-Bromo-1H-pyrrolo[2,3-c]pyridine
- Purity
- 97%
- Packaging
- 1g
- Price
- $69
- Updated
- 2021/12/16
- Product number
- FB137463
- Product name
- 4-Bromo-1H-pyrrolo[2,3-c]pyridine
- Packaging
- 100mg
- Price
- $70
- Updated
- 2021/12/16
- Product number
- FB137463
- Product name
- 4-Bromo-1H-pyrrolo[2,3-c]pyridine
- Packaging
- 250mg
- Price
- $100
- Updated
- 2021/12/16
4-bromo-1H-pyrrolo[2,3-c]pyridine Chemical Properties,Usage,Production
Synthesis
2-(3-bromo-5-nitropyridin-4-yl)-N, N-dimethylethylenamine (2.38 g, 8.78 mmol) and iron powder (~325 mesh, 2.45 g, 43.9 mmol) were stirred in acetic acid (25 mL). The red mixture was heated to reflux and turned grayish-green with a white precipitate. After refluxing for 45 min, the reaction was cooled, diluted with EtOAc (150 mL), filtered through Celite and rinsed with additional EtOAc. The filtrate was slowly basified to pH 8 with saturated aqueous NaHCO3, and the aqueous layer was extracted with EtOAc. The combined organics were washed with brine, dried (MgSO4), filtered, and concentrated in vacuo. Silica gel chromatography (eluding with 5% MeOH in EtOAc) afforded 4-bromo-1H-pyrrolo[2,3-c]pyridine (1.26 g, 73%) as a yellow solid.
References
[1] Patent: US2005/90529, 2005, A1. Location in patent: Page/Page column 82-83
[2] Patent: WO2010/145201, 2010, A1. Location in patent: Page/Page column 25
4-bromo-1H-pyrrolo[2,3-c]pyridine Preparation Products And Raw materials
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View Lastest Price from 4-bromo-1H-pyrrolo[2,3-c]pyridine manufacturers
- Product
- 4-bromo-1H-pyrrolo[2,3-c]pyridine 69872-17-9
- Price
- US $150.00-1000.00/g
- Min. Order
- 5g
- Purity
- 99%
- Supply Ability
- 30
- Release date
- 2024-07-10
- Product
- 4-Bromo-6-azaindole 69872-17-9
- Price
- US $1.00/g
- Min. Order
- 1g
- Purity
- 95-99%
- Supply Ability
- 1ton
- Release date
- 2020-01-10
- Product
- 4-Bromo-6-azaindole 69872-17-9
- Price
- US $1.00/g
- Min. Order
- 1g
- Purity
- 95-99%
- Supply Ability
- 1ton
- Release date
- 2020-01-09