(S)-Ketorolac
- Product Name
- (S)-Ketorolac
- CAS No.
- 66635-92-5
- Chemical Name
- (S)-Ketorolac
- Synonyms
- Ketorolac S-IsoMer;(S)-Ketorolac ISO 9001：2015 REACH;Ketorolac impurity 2/Ketorolac S-Isomer;Phosphorousacid,tris(1,5-dimethylethyl)ester;1H-Pyrrolizine-1-carboxylic acid, 5-benzoyl-2,3-dihydro-, (1S)-
- CBNumber
- CB62485724
- Molecular Formula
- C15H13NO3
- Formula Weight
- 255.27
- MOL File
- 66635-92-5.mol
(S)-Ketorolac Property
- Melting point:
- 160-167?C
- Boiling point:
- 493.2±40.0 °C(Predicted)
- Density
- 1.33±0.1 g/cm3(Predicted)
- storage temp.
- Refrigerator
- solubility
- Chloroform: Slightly; Ethanol: >1mg/ml; Methanol: Slightly
- form
- A crystalline solid
- pka
- 4.29±0.20(Predicted)
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Danger
- Hazard statements
-
H301Toxic if swalloed
- Precautionary statements
-
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P270Do not eat, drink or smoke when using this product.
P301+P310IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.
P405Store locked up.
P501Dispose of contents/container to..…
N-Bromosuccinimide Price
- Product number
- SML3299
- Product name
- S-Ketorolac
- Purity
- ≥98% (HPLC)
- Packaging
- 5MG
- Price
- $116
- Updated
- 2023/06/20
- Product number
- SML3299
- Product name
- S-Ketorolac
- Purity
- ≥98% (HPLC)
- Packaging
- 25MG
- Price
- $469
- Updated
- 2023/06/20
- Product number
- 11348
- Product name
- (S)-Ketorolac
- Purity
- ≥98%
- Packaging
- 1mg
- Price
- $106
- Updated
- 2024/03/01
- Product number
- 11348
- Product name
- (S)-Ketorolac
- Purity
- ≥98%
- Packaging
- 5mg
- Price
- $414
- Updated
- 2024/03/01
- Product number
- K235605
- Product name
- (S)-Ketorolac
- Packaging
- 2mg
- Price
- $155
- Updated
- 2021/12/16
(S)-Ketorolac Chemical Properties,Usage,Production
Description
(S)-Ketorolac is a non-selective COX inhibitor and non-steroidal anti-inflammatory drug (NSAID; IC50s = 0.1 and 2.7 μM for COX-1 and COX-2, respectively). (S)-Ketorolac is approximately twice as potent as the racemic mixture and 60 times more potent than (R)-ketorolac in a rat pain assay. (S)-Ketorolac is cleared from rat kidney and liver more quickly than (R)-ketorolac. Formulations containing ketorolac have been used to manage postoperative pain as well as an ophthalmic solution to treat ocular pain and inflammation.
Chemical Properties
Off-White Solid
Uses
The R-enantiomer of Ketorolac. The (S)-enantiomer is about 60 times more potent than (R)-enantiomer. Prostaglandin biosynthesis inhibitor. Analgesic; anti-inflammatory.
Uses
(S)-Ketorolac is the S-enantiomer of Ketorolac. The (S)-enantiomer is about 60 times more potent than (R)-enantiomer. Prostaglandin biosynthesis inhibitor. Analgesic; anti-inflammatory.
Definition
ChEBI: A 5-benzoyl-2,3-dihydro-1H-pyrrolizine-1-carboxylic acid that has S configuration. While (S)-ketorolac is a COX1 and COX2 inhibitor, both enantiomers exhibit analgesic effects. Racemic ketorolac, known s mply as ketorolac, is used (mainly as the tromethamine salt) as a potent analgesic for the short-term management of post-operative pain, and in eye drops to relieve the ocular itching associated with seasonal allergic conjunctivitis.
(S)-Ketorolac Preparation Products And Raw materials
Raw materials
Preparation Products
View Lastest Price from (S)-Ketorolac manufacturers
- Product
- (S)-Ketorolac 66635-92-5
- Price
- US $1.10/g
- Min. Order
- 1g
- Purity
- 99.0% min
- Supply Ability
- 100 tons min
- Release date
- 2021-05-25
- Product
- (S)-Ketorolac 66635-92-5
- Price
- US $1.10/g
- Min. Order
- 1g
- Purity
- 99.00%
- Supply Ability
- 100 Tons Min
- Release date
- 2021-10-21