ChemicalBook > CAS DataBase List > 5,7-difluorochroman-4-one

5,7-difluorochroman-4-one

Product Name
5,7-difluorochroman-4-one
CAS No.
844648-22-2
Chemical Name
5,7-difluorochroman-4-one
Synonyms
Tegoprazan Impurity 10;5,7-difluorochroman-4-one;Tigola produces impurity 10;5,7-difluoro-2,3-dihydrochromen-4-one;5,7-Difluoro-3,4-dihydro-4H-chromen-4-one;5,7-Difluoro-2,3-dihydro-4H-chromen-4-one;5,7-DIFLUORO-2,3-DIHYDRO-1-BENZOPYRAN-4-ONE;5,7-Difluoro-2,3-dihydro-4H-1-benzopyran-4-one;5,7-difluoro-3,4-dihydro-2H-1-benzopyran-4-one;4H-1-Benzopyran-4-one, 5,7-difluoro-2,3-dihydro-
CBNumber
CB62489782
Molecular Formula
C9H6F2O2
Formula Weight
184.14
MOL File
844648-22-2.mol
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5,7-difluorochroman-4-one Property

Boiling point:
283℃
Density 
1.392
Flash point:
121℃
storage temp. 
Sealed in dry,Room Temperature
Appearance
White to light yellow Solid
InChI
InChI=1S/C9H6F2O2/c10-5-3-6(11)9-7(12)1-2-13-8(9)4-5/h3-4H,1-2H2
InChIKey
OJVRCPGUGZXUAP-UHFFFAOYSA-N
SMILES
C1OC2=CC(F)=CC(F)=C2C(=O)C1
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Safety

HS Code 
2932990090
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Apolloscientific
Product number
PC201320
Product name
5,7-Difluorochroman-4-one
Purity
95%
Packaging
250mg
Price
$90
Updated
2021/12/16
AK Scientific
Product number
J55733
Product name
5,7-Difluorochroman-4-one
Packaging
250mg
Price
$95
Updated
2021/12/16
Apolloscientific
Product number
PC201320
Product name
5,7-Difluorochroman-4-one
Purity
95%
Packaging
1g
Price
$225
Updated
2021/12/16
AK Scientific
Product number
J55733
Product name
5,7-Difluorochroman-4-one
Packaging
1g
Price
$238
Updated
2021/12/16
SynQuest Laboratories
Product number
2H17-3-0B
Product name
5,7-Difluorochroman-4-one
Purity
95%
Packaging
1g
Price
$360
Updated
2021/12/16
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5,7-difluorochroman-4-one Chemical Properties,Usage,Production

Uses

5,7-Difluorochroman-4-one is used as a reagent in the prepaation of tetrazolinone compounds,used as pest control agents.

Synthesis

844648-19-7

844648-22-2

At 50 °C, 3-(3,5-difluorophenoxy)propionic acid (20.0 g, 99 mmol) was added to 60 mL of concentrated sulfuric acid in batches and stirred until completely dissolved. The resulting yellow-green solution was stirred continuously at 50 °C for 1.5 hours. Upon completion of the reaction, the mixture was cooled to room temperature and slowly poured into 800 mL of ice water. After standing for 1 hour, the colorless precipitate was collected by filtration and washed well with cold water. The resulting 5,7-difluorobenzodihydropyran-4-one was dried over phosphorus pentoxide to give 15.69 g of colorless solid in 86% yield.

References

[1] Patent: WO2008/151927, 2008, A2. Location in patent: Page/Page column 61
[2] Patent: KR2018/11830, 2018, A. Location in patent: Paragraph 0061; 0076; 0077
[3] Patent: US2005/38032, 2005, A1. Location in patent: Page/Page column 31

5,7-difluorochroman-4-one Preparation Products And Raw materials

Raw materials

Preparation Products

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5,7-difluorochroman-4-one Suppliers

DoEasy Pharma Co., Ltd.
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0571-0571-28806358 15397199029
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0571-89057225
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songxy@doepharma.com
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China
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Kaifeng Mingren Pharmaceutical Co.,LTD
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0371-65741762
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QQ:2860768577
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China
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2380
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Shandong Zhonghan Pharmaceutical Co.,Ltd.
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19862069201
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China
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Shandong Winner Biotechnology Co., Ltd.
Tel
15315319889
Email
wannaswsw@163.com
Country
China
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299
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58
Shanghai Yuanding Chem. Sci. & Tech. Co., Ltd.
Tel
21-57721279
Fax
QQ:14057904
Email
sales@shydchem.com.cn
Country
China
ProdList
998
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Adamas Reagent, Ltd.
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021-64823266
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China
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Shanghai Hanhong Scientific Co.,Ltd.
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021-54306202 13764082696
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China
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Daicel Chiral Technologies (China)CO.,LTD
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021-50460086-9 15921403865
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+86-21-50462321
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Tongchuang Pharma(Suzhou). Co., Ltd.
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0512-63263366 18912765016
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0512-6326 3366
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tongtf110@sina.com
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China
ProdList
993
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Hangzhou Sage Chemical Co., Ltd.
Tel
+86057186818502 13588463833
Fax
Pls mail us for more information!
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info@sagechem.com
Country
China
ProdList
10266
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View Lastest Price from 5,7-difluorochroman-4-one manufacturers

ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD
Product
5,7-difluorochroman-4-one 844648-22-2
Price
US $2.20-8.80/kg
Min. Order
1kg
Purity
99%min
Supply Ability
100kg
Release date
2025-06-12

844648-22-2, 5,7-difluorochroman-4-oneRelated Search:


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