Methyl 4-fluoro-3-(trifluoroMethyl)benzoate
- Product Name
- Methyl 4-fluoro-3-(trifluoroMethyl)benzoate
- CAS No.
- 176694-36-3
- Chemical Name
- Methyl 4-fluoro-3-(trifluoroMethyl)benzoate
- Synonyms
- Methyl 4-fluoro-3-(trifluoroMethyl)benzoate;4-Fluoro-3-trifluoromethylbenzoic acid methyl ester;Benzoic acid, 4-fluoro-3-(trifluoroMethyl)-, Methyl ester
- CBNumber
- CB62550325
- Molecular Formula
- C9H6F4O2
- Formula Weight
- 222.14
- MOL File
- 176694-36-3.mol
Methyl 4-fluoro-3-(trifluoroMethyl)benzoate Property
- storage temp.
- Sealed in dry,Room Temperature
- Appearance
- Colorless to light yellow Liquid
Safety
- HS Code
- 2916399090
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
- Precautionary statements
-
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P332+P313IF SKIN irritation occurs: Get medical advice/attention.
P337+P313IF eye irritation persists: Get medical advice/attention.
N-Bromosuccinimide Price
- Product number
- M305763
- Product name
- Methyl4-Fluoro-3-(trifluoromethyl)benzoate
- Packaging
- 100mg
- Price
- $75
- Updated
- 2021/12/16
- Product number
- CS-W022853
- Product name
- Methyl4-fluoro-3-(trifluoromethyl)benzoate
- Purity
- 99.18%
- Packaging
- 25g
- Price
- $143
- Updated
- 2021/12/16
- Product number
- 074664
- Product name
- Methyl 4-fluoro-3-(trifluoromethyl)benzoate
- Purity
- 95+%
- Packaging
- 25g
- Price
- $370
- Updated
- 2021/12/16
- Product number
- CS-W022853
- Product name
- Methyl4-fluoro-3-(trifluoromethyl)benzoate
- Purity
- 99.18%
- Packaging
- 100g
- Price
- $385
- Updated
- 2021/12/16
- Product number
- HCH0142627
- Product name
- METHYL-4-FLUORO-3-(TRIFLUOROMETHYL)BENZOATE
- Purity
- 95.00%
- Packaging
- 250MG
- Price
- $831.6
- Updated
- 2021/12/16
Methyl 4-fluoro-3-(trifluoroMethyl)benzoate Chemical Properties,Usage,Production
Synthesis
67-56-1
67515-55-3
176694-36-3
Concentrated hydrochloric acid was slowly added to a stirred solution of 4-fluoro-3-(trifluoromethyl)benzoic acid (10.0 g, 48.1 mmol) in methanol (100 mL). Subsequently, sulfuric acid (4 mL, 73.4 mmol) was added dropwise at room temperature and the reaction mixture was heated to reflux for 5 hours. Upon completion of the reaction, 200 mL of aqueous sodium bicarbonate was added to neutralize the reaction mixture, which was then extracted with ethyl acetate (100 mL × 3). The organic phases were combined, washed with saturated saline (100 mL × 2), dried over anhydrous sodium sulfate, and concentrated under reduced pressure to afford the title compound methyl 4-fluoro-3-trifluoromethylbenzoate (9.4 g, 88% yield) as a light yellow oil.1H NMR (400 MHz, CDCl3) δ 8.33 (dd, J = 6.8, 1.6 Hz, 1H), 8.28- 8.22 (m, 1H), 7.28 (t, 1H), 3.95 (s, 3H).
References
[1] Patent: WO2014/206344, 2014, A1. Location in patent: Page/Page column 100
[2] Patent: WO2006/50830, 2006, A1. Location in patent: Page/Page column 47
Methyl 4-fluoro-3-(trifluoroMethyl)benzoate Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from Methyl 4-fluoro-3-(trifluoroMethyl)benzoate manufacturers
- Product
- Methyl 4-fluoro-3-(trifluoroMethyl)benzoate 176694-36-3
- Price
- US $15.00-10.00/KG
- Min. Order
- 1KG
- Purity
- 99%+ HPLC
- Supply Ability
- Monthly supply of 1 ton
- Release date
- 2021-07-11
- Product
- Methyl 4-fluoro-3-(trifluoromethyl)benzoate 176694-36-3
- Price
- US $1.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 200kg
- Release date
- 2020-01-09