(S)-2-((Methoxycarbonyl)aMino)-3-Methylbutanoic acid
- Product Name
- (S)-2-((Methoxycarbonyl)aMino)-3-Methylbutanoic acid
- CAS No.
- 74761-42-5
- Chemical Name
- (S)-2-((Methoxycarbonyl)aMino)-3-Methylbutanoic acid
- Synonyms
- (methoxycarbonyl)-L-valine;MOC-L-Valine;N-(Methoxycarbonyl)-L-valine;MOC-L;MOC-Val;MOC-L-Val;Moc-Val-OH;Moc-L-Val-OH;Methoxycarbonyl valine;Oliceridine Impurity 8
- CBNumber
- CB62593005
- Molecular Formula
- C7H13NO4
- Formula Weight
- 175.18
- MOL File
- 74761-42-5.mol
(S)-2-((Methoxycarbonyl)aMino)-3-Methylbutanoic acid Property
- Melting point:
- 109.0 to 113.0 °C
- Boiling point:
- 315.9±25.0 °C(Predicted)
- Density
- 1.154±0.06 g/cm3(Predicted)
- storage temp.
- Sealed in dry,Room Temperature
- form
- powder to crystal
- pka
- 4.44±0.10(Predicted)
- color
- White to Almost white
- InChI
- InChI=1S/C7H13NO4/c1-4(2)5(6(9)10)8-7(11)12-3/h4-5H,1-3H3,(H,8,11)(H,9,10)/t5-/m0/s1
- InChIKey
- CEFVHPDFGLDQKU-YFKPBYRVSA-N
- SMILES
- C(O)(=O)[C@H](C(C)C)NC(OC)=O
Safety
- HS Code
- 2924297099
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- M2857
- Product name
- N-(Methoxycarbonyl)-L-valine
- Purity
- >98.0%(HPLC)(T)
- Packaging
- 5g
- Price
- $30
- Updated
- 2024/03/01
- Product number
- M2857
- Product name
- N-(Methoxycarbonyl)-L-valine
- Purity
- >98.0%(HPLC)(T)
- Packaging
- 25g
- Price
- $51
- Updated
- 2024/03/01
- Product number
- M219945
- Product name
- (S)-2-((Methoxycarbonyl)amino)-4-methylbutanoicAcid
- Packaging
- 1g
- Price
- $60
- Updated
- 2021/12/16
- Product number
- M219945
- Product name
- (S)-2-((Methoxycarbonyl)amino)-4-methylbutanoicAcid
- Packaging
- 5g
- Price
- $75
- Updated
- 2021/12/16
- Product number
- AS90227
- Product name
- (S)-2-[(Methoxycarbonyl)amino]-3-methylbutyric Acid
- Purity
- 98+% ee
- Packaging
- 100g
- Price
- $113
- Updated
- 2021/12/16
(S)-2-((Methoxycarbonyl)aMino)-3-Methylbutanoic acid Chemical Properties,Usage,Production
Uses
(S)-2-((Methoxycarbonyl)aMino)-3-Methylbutanoic acid can be used as Ledipasvir Intermediate, mainly used in laboratory R&D process and chemical production process.
Synthesis
Na2CO3 (1.83 g, 17.2 mmol) was added to an aq solution of NaOH (33 mL of 1 M/H2O, 33 mmol) and L-valine (3.900 g, 33.29 mmol) and the resulting solution was cooled with ice-water bath. Methyl chloroformate (2.8 mL, 36.1 mmol) was added dropwise, the cooling bath was removed and the reaction mixture was stirred at ambient temperature for 3.25 h. The reaction mixture was washed with ether (3x17 mL), and the aqueous phase was cooled with ice-water bath and acidified with conc HCl to a pH of 1-2, and extracted with CH2Cl2 (3x17 mL). The organic phase was dried (anhyd MgSO4), filtered, and concentrated in vacuo. Cap-1 as a white solid (5.00 g, 86%).
(S)-2-((Methoxycarbonyl)aMino)-3-Methylbutanoic acid Preparation Products And Raw materials
Raw materials
Preparation Products
(S)-2-((Methoxycarbonyl)aMino)-3-Methylbutanoic acid Suppliers
View Lastest Price from (S)-2-((Methoxycarbonyl)aMino)-3-Methylbutanoic acid manufacturers
- Product
- MOC-L-Valine 74761-42-5
- Price
- US $0.00/Kg/Drum
- Min. Order
- 1KG
- Purity
- 98.5%min
- Supply Ability
- 10 tons
- Release date
- 2021-08-09
- Product
- (S)-2-((Methoxycarbonyl)aMino)-3-Methylbutanoic acid 74761-42-5
- Price
- US $50.00/KG
- Min. Order
- 25KG
- Purity
- 98
- Supply Ability
- 200ton
- Release date
- 2023-08-17
- Product
- MOC-L-Valine 74761-42-5
- Price
- US $0.00/kg
- Min. Order
- 1kg
- Purity
- 99%
- Supply Ability
- 5T/month
- Release date
- 2023-07-26