Cyclopenta[c]pyrrole-2(1H)-carboxylic acid, hexahydro-5-hydroxy-, 1,1-diMethylethyl ester

Product Name: Cyclopenta[c]pyrrole-2(1H)-carboxylic acid, hexahydro-5-hydroxy-, 1,1-diMethylethyl ester
CAS No.: 203663-25-6
Chemical Name: Cyclopenta[c]pyrrole-2(1H)-carboxylic acid, hexahydro-5-hydroxy-, 1,1-diMethylethyl ester
Synonyms: 2-Boc-octahydrocyclopenta[c]pyrrol-5-ol;tert-butyl 5-hydroxy-octahydrocyclopenta[c]pyrrole-2-carboxylate;tert-butyl 5-hydroxy-hexahydrocyclopenta[c]pyrrole-2(1H)-carboxylate;5-Hydroxyhexahydrocyclopenta[c]pyrrole-2(1H)-carboxylic acid tert-butyl ester;tert-butyl 5-hydroxy-3,3a,4,5,6,6a-hexahydro-1H-cyclopenta[c]pyrrole-2-carboxylate;Cyclopenta[c]pyrrole-2(1H)-carboxylic acid, hexahydro-5-hydroxy-, 1,1-diMethylethyl ester
CBNumber: CB62603931
Molecular Formula: C12H21NO3
Formula Weight: 227.3
MOL File: 203663-25-6.mol

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Cyclopenta[c]pyrrole-2(1H)-carboxylic acid, hexahydro-5-hydroxy-, 1,1-diMethylethyl ester Property

storage temp.: 2-8°C
Appearance: White to off-white Solid
InChI: InChI=1S/C12H21NO3/c1-12(2,3)16-11(15)13-6-8-4-10(14)5-9(8)7-13/h8-10,14H,4-7H2,1-3H3
InChIKey: DIDQRACXWWEPDZ-UHFFFAOYSA-N
SMILES: N1(C(OC(C)(C)C)=O)CC2CC(O)CC2C1

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H317May cause an allergic skin reaction

Precautionary statements

P280Wear protective gloves/protective clothing/eye protection/face protection.

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N-Bromosuccinimide Price

TRC

Product number: B943540
Product name: tert-Butyl5-Hydroxy-hexahydrocyclopenta[C]pyrrole-2(1h)-carboxylate
Packaging: 100mg
Price: $200
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: CHM1554717
Product name: TERT-BUTYL-5-HYDROXY-OCTAHYDROCYCLOPENTA[C]PYRROLE-2-CARBOXYLATE
Purity: 95.00%
Packaging: 5MG
Price: $451.44
Updated: 2021/12/16

Ambeed

Product number: A168950
Product name: tert-Butyl5-hydroxyhexahydrocyclopenta[c]pyrrole-2(1H)-carboxylate
Purity: 95%
Packaging: 100mg
Price: $70
Updated: 2021/12/16

Ambeed

Product number: A168950
Product name: tert-Butyl5-hydroxyhexahydrocyclopenta[c]pyrrole-2(1H)-carboxylate
Purity: 95%
Packaging: 250mg
Price: $110
Updated: 2021/12/16

Ambeed

Product number: A168950
Product name: tert-Butyl5-hydroxyhexahydrocyclopenta[c]pyrrole-2(1H)-carboxylate
Purity: 95%
Packaging: 1g
Price: $230
Updated: 2021/12/16

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Cyclopenta[c]pyrrole-2(1H)-carboxylic acid, hexahydro-5-hydroxy-, 1,1-diMethylethyl ester Chemical Properties,Usage,Production

Synthesis

148404-28-8

203663-25-6

Step 4) 2-(tert-butoxycarbonyl)hexahydrocyclopenta[c]pyrrol-5(1H)-one (0.9 g, 4 mmol) was dissolved in EtOH (20 mL), and NaBH4 (0.82 g, 21.7 mmol) was added in batches. The reaction mixture was stirred at room temperature for 4.5 h and then concentrated under vacuum. The residue was diluted with EtOAc (50 mL) and washed sequentially with H2O (50 mL) and brine (50 mL). The resulting organic phase was dried over anhydrous Na2SO4 and concentrated in vacuum to afford tert-butyl 5-hydroxy-hexahydrocyclopenta[c]pyrrole-2(1H)-carboxylate as a yellow oil (0.99 g, 100% yield), which was used directly in the subsequent reaction.

References

[1] Patent: WO2013/138210, 2013, A1. Location in patent: Paragraph 0296
[2] Patent: WO2018/133858, 2018, A1. Location in patent: Paragraph 00207
[3] Patent: EP3401315, 2018, A1. Location in patent: Paragraph 0157; 0161
[4] Patent: US6518423, 2003, B1
[5] Chemical Biology and Drug Design, 2012, vol. 80, # 3, p. 388 - 397

Cyclopenta[c]pyrrole-2(1H)-carboxylic acid, hexahydro-5-hydroxy-, 1,1-diMethylethyl ester Preparation Products And Raw materials

Raw materials

Preparation Products

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Cyclopenta[c]pyrrole-2(1H)-carboxylic acid, hexahydro-5-hydroxy-, 1,1-diMethylethyl ester Suppliers

China 40 India 1 United States 3 Global 44

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203663-25-6, Cyclopenta[c]pyrrole-2(1H)-carboxylic acid, hexahydro-5-hydroxy-, 1,1-diMethylethyl esterRelated Search:

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Cyclopenta[c]pyrrole-2(1H)-carboxylic acid, hexahydro-5-hydroxy-, 1,1-diMethylethyl ester

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5-Hydroxyhexahydrocyclopenta[c]pyrrole-2(1H)-carboxylic acid tert-butyl ester

tert-butyl 5-hydroxy-3,3a,4,5,6,6a-hexahydro-1H-cyclopenta[c]pyrrole-2-carboxylate

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203663-25-6