Cyclopenta[c]pyrrole-2(1H)-carboxylic acid, hexahydro-5-hydroxy-, 1,1-diMethylethyl ester
- Product Name
- Cyclopenta[c]pyrrole-2(1H)-carboxylic acid, hexahydro-5-hydroxy-, 1,1-diMethylethyl ester
- CAS No.
- 203663-25-6
- Chemical Name
- Cyclopenta[c]pyrrole-2(1H)-carboxylic acid, hexahydro-5-hydroxy-, 1,1-diMethylethyl ester
- Synonyms
- 2-Boc-octahydrocyclopenta[c]pyrrol-5-ol;tert-butyl 5-hydroxy-octahydrocyclopenta[c]pyrrole-2-carboxylate;tert-butyl 5-hydroxy-hexahydrocyclopenta[c]pyrrole-2(1H)-carboxylate;5-Hydroxyhexahydrocyclopenta[c]pyrrole-2(1H)-carboxylic acid tert-butyl ester;tert-butyl 5-hydroxy-3,3a,4,5,6,6a-hexahydro-1H-cyclopenta[c]pyrrole-2-carboxylate;Cyclopenta[c]pyrrole-2(1H)-carboxylic acid, hexahydro-5-hydroxy-, 1,1-diMethylethyl ester
- CBNumber
- CB62603931
- Molecular Formula
- C12H21NO3
- Formula Weight
- 227.3
- MOL File
- 203663-25-6.mol
Cyclopenta[c]pyrrole-2(1H)-carboxylic acid, hexahydro-5-hydroxy-, 1,1-diMethylethyl ester Property
- storage temp.
- 2-8°C
- Appearance
- White to off-white Solid
- InChI
- InChI=1S/C12H21NO3/c1-12(2,3)16-11(15)13-6-8-4-10(14)5-9(8)7-13/h8-10,14H,4-7H2,1-3H3
- InChIKey
- DIDQRACXWWEPDZ-UHFFFAOYSA-N
- SMILES
- N1(C(OC(C)(C)C)=O)CC2CC(O)CC2C1
N-Bromosuccinimide Price
- Product number
- B943540
- Product name
- tert-Butyl5-Hydroxy-hexahydrocyclopenta[C]pyrrole-2(1h)-carboxylate
- Packaging
- 100mg
- Price
- $200
- Updated
- 2021/12/16
- Product number
- CHM1554717
- Product name
- TERT-BUTYL-5-HYDROXY-OCTAHYDROCYCLOPENTA[C]PYRROLE-2-CARBOXYLATE
- Purity
- 95.00%
- Packaging
- 5MG
- Price
- $451.44
- Updated
- 2021/12/16
- Product number
- A168950
- Product name
- tert-Butyl5-hydroxyhexahydrocyclopenta[c]pyrrole-2(1H)-carboxylate
- Purity
- 95%
- Packaging
- 5g
- Price
- $681
- Updated
- 2021/12/16
- Product number
- CM327684
- Product name
- tert-butyl5-hydroxy-3,3a,4,5,6,6a-hexahydro-1H-cyclopenta[c]pyrrole-2-carboxylate
- Purity
- 95%+
- Packaging
- 5g
- Price
- $1031
- Updated
- 2021/12/16
- Product number
- CD11168855
- Product name
- tert-Butyl5-hydroxyhexahydrocyclopenta[c]pyrrole-2(1H)-carboxylate
- Purity
- 95+%
- Packaging
- 5g
- Price
- $1089
- Updated
- 2021/12/16
Cyclopenta[c]pyrrole-2(1H)-carboxylic acid, hexahydro-5-hydroxy-, 1,1-diMethylethyl ester Chemical Properties,Usage,Production
Synthesis
148404-28-8
203663-25-6
Step 4) 2-(tert-butoxycarbonyl)hexahydrocyclopenta[c]pyrrol-5(1H)-one (0.9 g, 4 mmol) was dissolved in EtOH (20 mL), and NaBH4 (0.82 g, 21.7 mmol) was added in batches. The reaction mixture was stirred at room temperature for 4.5 h and then concentrated under vacuum. The residue was diluted with EtOAc (50 mL) and washed sequentially with H2O (50 mL) and brine (50 mL). The resulting organic phase was dried over anhydrous Na2SO4 and concentrated in vacuum to afford tert-butyl 5-hydroxy-hexahydrocyclopenta[c]pyrrole-2(1H)-carboxylate as a yellow oil (0.99 g, 100% yield), which was used directly in the subsequent reaction.
References
[1] Patent: WO2013/138210, 2013, A1. Location in patent: Paragraph 0296
[2] Patent: WO2018/133858, 2018, A1. Location in patent: Paragraph 00207
[3] Patent: EP3401315, 2018, A1. Location in patent: Paragraph 0157; 0161
[4] Patent: US6518423, 2003, B1
[5] Chemical Biology and Drug Design, 2012, vol. 80, # 3, p. 388 - 397
Cyclopenta[c]pyrrole-2(1H)-carboxylic acid, hexahydro-5-hydroxy-, 1,1-diMethylethyl ester Preparation Products And Raw materials
Raw materials
Preparation Products
Cyclopenta[c]pyrrole-2(1H)-carboxylic acid, hexahydro-5-hydroxy-, 1,1-diMethylethyl ester Suppliers
- Tel
- +1-5166625404;
- Fax
- 1-516-927-0118
- Info@alfa-chemistry.com
- Country
- United States
- ProdList
- 20405
- Advantage
- 58
- Tel
- tp@aladdinsci.com
- Country
- United States
- ProdList
- 52923
- Advantage
- 58
- Tel
- --
- Fax
- --
- info@synthonix.com
- Country
- United States
- ProdList
- 6872
- Advantage
- 58