ChemicalBook > CAS DataBase List > 4-c]pyridine

4-c]pyridine

Product Name
4-c]pyridine
CAS No.
1357947-08-0
Chemical Name
4-c]pyridine
Synonyms
5-broMo-3-iodo-1H-pyrazolo[3,4-c]pyridine;1H-Pyrazolo[3,4-c]pyridine, 5-bromo-3-iodo-
CBNumber
CB62616490
Molecular Formula
C6H3BrIN3
Formula Weight
323.92
MOL File
1357947-08-0.mol
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4-c]pyridine Property

Boiling point:
458.7±40.0 °C(Predicted)
Density 
2.559±0.06 g/cm3(Predicted)
storage temp. 
under inert gas (nitrogen or Argon) at 2–8 °C
form 
solid
pka
7.72±0.40(Predicted)
Appearance
Off-white to light yellow Solid
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Safety

Hazard Codes 
Xn
Risk Statements 
22
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

Precautionary statements

P280Wear protective gloves/protective clothing/eye protection/face protection.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

TRC
Product number
B681098
Product name
5-Bromo-3-Iodo-1h-Pyrazolo[3,4-C]Pyridine
Packaging
50mg
Price
$90
Updated
2021/12/16
Matrix Scientific
Product number
189029
Product name
5-Bromo-3-iodo-1H-pyrazolo[3,4-c]pyridine
Packaging
1g
Price
$556
Updated
2021/12/16
Matrix Scientific
Product number
189029
Product name
5-Bromo-3-iodo-1H-pyrazolo[3,4-c]pyridine
Packaging
5g
Price
$1800
Updated
2021/12/16
Matrix Scientific
Product number
189029
Product name
5-Bromo-3-iodo-1H-pyrazolo[3,4-c]pyridine
Packaging
10g
Price
$2880
Updated
2021/12/16
Ambeed
Product number
A117844
Product name
5-Bromo-3-iodo-1H-pyrazolo[3,4-c]pyridine
Purity
97%
Packaging
100mg
Price
$38
Updated
2021/12/16
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4-c]pyridine Chemical Properties,Usage,Production

Synthesis

Step I. Preparation of 5-bromo-1H-pyrazolo[3,4-c]pyridine

To a solution of 6-bromo-4-methylpyridin-3-amine (7.76 g, 0.0415 mol) in acetic acid (412.8 mL, 7.260 mol) was added 4.0 ml of a 4.0 ml aqueous solution of sodium nitrite (2.87 g, 0.0416 mol) (Bioorg. Med. Chem. 15 (2007) 2441- 2452). The reaction mixture was stirred for 15 min and allowed to stand at room temperature (rt) for 2 days (d). The reaction mixture was concentrated and diluted with EtOAc and then washed with NaHCO3 and brine. The organic layer was dried over Na2SO4, filtered and concentrated. The crude was purified by chromatography (DCM/ MeOH, eluting with 5% MeOH) to afford 5-bromo-1H-pyrazolo[3,4-c]pyridine (79.1% yield).

Step II. Preparation of 5-bromo-3-iodo-1H-pyrazolo[3,4-c]pyridine

A solution containing 5-bromo-1H-pyrazolo[3,4-c]pyridine (168.0 g, 848.4 mmol) and NIS (286.3 g, 1.27 mol) in DMF (1.2 L) was stirred at room temperature. The reaction mixture was poured into water then filtered. The solid was washed with water and 5% Na2S2O5. The crude product was dried under high vacuum overnight to give 5-bromo-3-iodo-1H-pyrazolo[3,4-c]pyridine.

4-c]pyridine Preparation Products And Raw materials

Raw materials

Preparation Products

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4-c]pyridine Suppliers

China 59 India 2 United States 4 Global 65
J & K SCIENTIFIC LTD.
Tel
18210857532; 18210857532
Fax
86-10-82849933
Email
jkinfo@jkchemical.com
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China
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96815
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76
Adamas Reagent, Ltd.
Tel
400-6009262 15618770481
Fax
021-64823266
Email
yhx@titansci.com
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China
ProdList
14100
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59
Shanghai Hanhong Scientific Co.,Ltd.
Tel
021-54306202 13764082696
Email
info@hanhongsci.com
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China
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42934
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64
Bide Pharmatech Ltd.
Tel
400-400-164-7117 18317119277
Fax
+86-21-61629029
Email
product02@bidepharm.com
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China
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Nantong MYBio-pharm. Co., Ltd.
Tel
0513-85921823 18662920231
Fax
86-513-85012876
Email
sales@ntminyanmedical.com
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China
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4323
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Credit Asia Chemical Co., Ltd.
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+86 (21) 61124340
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+86 (21) 6129-4103
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China
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Bellen Chemistry Co., Ltd.
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010-60400365-8001 15910885229
Fax
010-60400361
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service@bellenchem.com
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China
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Jiaxing Rich Biological Technology Co., Ltd.
Tel
0573-11111111-1111 18969316891
Fax
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richmol@163.com
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China
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457
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SuZhou ShiYa Biopharmaceuticals, Inc.
Tel
0512-0512-52358471 17715136450
Fax
05125235 6881
Email
sales@shiyabiopharm.com
Country
China
ProdList
12127
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58
Shanghai YuanYe Biotechnology Co., Ltd.
Tel
021-61312847; 18021002903
Fax
QQ:3008007432
Email
3008007409@qq.com
Country
China
ProdList
89689
Advantage
60
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View Lastest Price from 4-c]pyridine manufacturers

Career Henan Chemical Co
Product
4-c]pyridine 1357947-08-0
Price
US $1.00/g
Min. Order
1g
Purity
99%
Supply Ability
200kg
Release date
2020-01-14

1357947-08-0, 4-c]pyridineRelated Search:

5-bromo-3-iodo-1H-pyrazolo[3,4-b]pyridine 4-Iodopyrazole 3-BROMO-1H-PYRAZOLE

  • 5-broMo-3-iodo-1H-pyrazolo[3,4-c]pyridine
  • 1H-Pyrazolo[3,4-c]pyridine, 5-bromo-3-iodo-
  • 1357947-08-0