Phenol, 2,4-bis(1,1-diMethylethyl)-5-nitro-

Product Name: Phenol, 2,4-bis(1,1-diMethylethyl)-5-nitro-
CAS No.: 873055-57-3
Chemical Name: Phenol, 2,4-bis(1,1-diMethylethyl)-5-nitro-
Synonyms: Ivacaftor Impurity 3;2,4-di-tert-butyl-5-nitro-phenol(97%);2,4-Bis(2-methyl-2-propanyl)-5-nitrophenol;Phenol, 2,4-bis(1,1-diMethylethyl)-5-nitro-
CBNumber: CB62624813
Molecular Formula: C14H21NO3
Formula Weight: 251.32
MOL File: 873055-57-3.mol

More

Less

Phenol, 2,4-bis(1,1-diMethylethyl)-5-nitro- Property

Boiling point:: 337.9±42.0 °C(Predicted)
Density: 1.078±0.06 g/cm3(Predicted)
storage temp.: 2-8°C
pka: 10.05±0.24(Predicted)
form: solid
color: Yellow

More

Less

Safety

HS Code: 2905599890

More

Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H332Harmful if inhaled

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

More

Less

N-Bromosuccinimide Price

Matrix Scientific

Product number: 058227
Product name: 2,4-Di-tert-butyl-5-nitrophenol
Purity: >95%
Packaging: 500mg
Price: $190
Updated: 2021/12/16

Matrix Scientific

Product number: 058227
Product name: 2,4-Di-tert-butyl-5-nitrophenol
Purity: >95%
Packaging: 1g
Price: $293
Updated: 2021/12/16

AK Scientific

Product number: 1199AF
Product name: 2,4-Di-tert-butyl-5-nitrophenol
Packaging: 1g
Price: $445
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: CHM0387800
Product name: 2,4-DI-TERT-BUTYL-5-NITROPHENOL
Purity: 95.00%
Packaging: 5MG
Price: $498.04
Updated: 2021/12/16

SynQuest Laboratories

Product number: 4754-1-0H
Product name: 2,4-Di-tert-butyl-5-nitrophenol
Packaging: 1g
Price: $656
Updated: 2021/12/16

More

Less

Phenol, 2,4-bis(1,1-diMethylethyl)-5-nitro- Chemical Properties,Usage,Production

Synthesis

873055-55-1

873055-56-2

873055-57-3

20039-94-5

The general procedure for the synthesis of 2,4-di-tert-butyl-5-nitrophenyl methyl carbonate and compound (CAS: 873055-56-2) from 2,4-di-tert-butyl-5-nitrophenol and 2,4-bis(tert-butyl)-6-nitrophenol was as follows. ester mixture (4.2 g, 12.9 mmol) was dissolved in methanol (65 mL) and potassium hydroxide (2.0 g, 36 mmol) was added. The reaction mixture was stirred at room temperature for 2 hours. Subsequently, the reaction mixture was acidified to pH 2-3 by addition of concentrated hydrochloric acid. the acidified mixture was partitioned between water and ether. The ether layer was separated, dried over magnesium sulfate, concentrated, and purified by column chromatography (0-5% ethyl acetate-hexane) to afford 2,4-di-tert-butyl-5-nitrophenol (1.31 g, two-step yield 29%) and 2,4-di-tert-butyl-6-nitrophenol.1H NMR (400 MHz, DMSO-d6) data for 2,4-di-tert-butyl-5-nitrophenol: δ 10.14 (s, 1H, OH), 7.34 (s, 1H), 6.83 (s, 1H), 1.36 (s, 9H), 1.30 (s, 9H).1H NMR (400 MHz, CDCl3) data of 2,4-di-tert-butyl-6-nitrophenol: δ 11.48 (s, 1H), 7.98 (d, J = 2.5Hz, 1H). 7.66 (d, J = 2.4 Hz, 1H), 1.47 (s, 9H), 1.34 (s, 9H).

References

[1] Patent: US2011/98311, 2011, A1
[2] Patent: US2008/90864, 2008, A1. Location in patent: Page/Page column 8
[3] Patent: WO2007/79139, 2007, A2. Location in patent: Page/Page column 47; 48

Phenol, 2,4-bis(1,1-diMethylethyl)-5-nitro- Preparation Products And Raw materials

Raw materials

Preparation Products

More

Less

Phenol, 2,4-bis(1,1-diMethylethyl)-5-nitro- Suppliers

China 49 India 1 United Kingdom 3 United States 5 Global 58

Adamas Reagent, Ltd.

Tel: 400-6009262 16621234537
Fax: 021-64823266
Email: chenyj@titansci.com
Country: China
ProdList: 14101
Advantage: 59

Nanjing JinruiJiuAn Biotechnology Co., Ltd.

Tel: 025-58196018 800028039
Fax: 025-83453306
Email: sales@fartop.net
Country: China
ProdList: 2229
Advantage: 55

shanghai aokchem co., ltd

Tel: 021-68712331 39130253
Fax: 18621350903
Email: aokchem@gmail.com
Country: China
ProdList: 332
Advantage: 58

ShangHai Onsyn-Chemical Technology Co., Ltd.

Tel: 021-58359326 15900795984
Fax: +86-21-58359326
Email: angsihuaxue@126.com
Country: China
ProdList: 252
Advantage: 55

Shanghai MOF Chemical Tech Limited

Tel: 13661494087 18964793018
Fax: 86-021-51821718 QQ：2427604606
Email: sales@mof-chemicals.com
Country: China
ProdList: 293
Advantage: 55

Shanghai YuanYe Biotechnology Co., Ltd.

Tel: 021-61312847; 18021002903
Fax: QQ:3008007432
Email: 3008007409@qq.com
Country: China
ProdList: 71826
Advantage: 60

Grader reagent

Tel: 18221735425
Email: sales@xinpingchem.com
Country: China
ProdList: 9942
Advantage: 58

Jinan elephant international trading co., LTD

Tel
Fax: -
Email: 13006575422@163.com
Country: China
ProdList: 6355
Advantage: 58

Amadis Chemical Company Limited

Tel: 571-89925085
Fax: 0086-571-89925065
Email: sales@amadischem.com
Country: China
ProdList: 131957
Advantage: 58

Dezhou LonWel Pharmaceutical Technology Co., Ltd.

Tel: 13761310616
Fax: QQ: 39324283
Email: 39324283@qq.com
Country: China
ProdList: 1629
Advantage: 58

More

Less

View Lastest Price from Phenol, 2,4-bis(1,1-diMethylethyl)-5-nitro- manufacturers

Career Henan Chemical Co

Product: 2,4-Bis(2-methyl-2-propanyl)-5-nitrophenol 873055-57-3
Price: US $9.80/KG
Min. Order: 1KG
Purity: ≥98%
Supply Ability: 20 tons
Release date: 2020-01-02

873055-57-3, Phenol, 2,4-bis(1,1-diMethylethyl)-5-nitro-Related Search:

2,4-di-tert-butyl-5-nitrophenyl methyl carbonate 4-HYDROXY-QUINOLINE-3-CARBOXYLIC ACID METHYL ESTER 2-PHENYLAMINOMETHYLENE-MALONIC ACIDDIETHYL ESTER 5-AMino-2,4-di-tert-butylphenol 4-OXO-1,4-DIHYDROQUINOLINE-3-CARBOXYLIC ACID VX-770

Phenol, 2,4-bis(1,1-diMethylethyl)-5-nitro-

2,4-di-tert-butyl-5-nitro-phenol(97%)

2,4-Bis(2-methyl-2-propanyl)-5-nitrophenol

Ivacaftor Impurity 3

873055-57-3