5-AMino-2,4-di-tert-butylphenol

Product Name: 5-AMino-2,4-di-tert-butylphenol
CAS No.: 873055-58-4
Chemical Name: 5-AMino-2,4-di-tert-butylphenol
Synonyms: VX-770 intermediate;4,6-dichloropyridazin-4-ol;2,4-ditert-butyl-5-aminophenol;5-AMino-2,4-di-tert-butylphenol;5-Amino-2,4-ditertiarybutyphenol;5-Amino-2,4-ditertiarybutylphenol;5-Amino-2,4-bis(2-methyl-2-propanyl)phenol;Phenol, 5-amino-2,4-bis(1,1-dimethylethyl)-;2,4-Di-tert-butyl-5-aMinophenyl Methyl carbonate;5-amino-2,4-di-tert-butylphenol hydrochloride (base)
CBNumber: CB52637683
Molecular Formula: C14H23NO
Formula Weight: 221.34
MOL File: 873055-58-4.mol

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5-AMino-2,4-di-tert-butylphenol Property

Boiling point:: 319.7±30.0 °C(Predicted)
Density: 0.990±0.06 g/cm3(Predicted)
storage temp.: 2-8°C(protect from light)
pka: 11.63±0.23(Predicted)
InChI: InChI=1S/C14H23NO/c1-13(2,3)9-7-10(14(4,5)6)12(16)8-11(9)15/h7-8,16H,15H2,1-6H3
InChIKey: BKSDHPHOWDUJNB-UHFFFAOYSA-N
SMILES: C1(O)=CC(N)=C(C(C)(C)C)C=C1C(C)(C)C

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

TRC

Product number: A604628
Product name: 5-Amino-2,4-di-tert-butylphenol
Packaging: 100mg
Price: $295
Updated: 2021/12/16

TRC

Product number: A604628
Product name: 5-Amino-2,4-di-tert-butylphenol
Packaging: 250mg
Price: $605
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: CHM0386179
Product name: 5-AMINO-2,4-DI-TERT-BUTYLPHENOL
Purity: 95.00%
Packaging: 5MG
Price: $500.94
Updated: 2021/12/16

Chemcia Scientific

Product number: CC00-7587
Product name: 5-Amino-2,4-di-tert-butyl-phenol
Purity: 95%
Packaging: 25g
Price: $540
Updated: 2021/12/16

Ambeed

Product number: A601459
Product name: 5-Amino-2,4-di-tert-butylphenol
Purity: 95+%
Packaging: 100mg
Price: $40
Updated: 2021/12/16

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5-AMino-2,4-di-tert-butylphenol Chemical Properties,Usage,Production

Uses

5-Amino-2,4-di-tert-butylphenol is an intermediate used in the preparation of ivacaftor via condensation of oxo dihydroquinoline carboxylic acid with amino ditert butylphenol.

Synthesis

To a refluxing solution of 2,4-di-tert-butyl-5-nitro-phenol (1.86 g, 7.40 mmol) and ammonium formate (1.86 g) in ethanol (75 mL) was added Pd-5% wt on activated carbon (900 mg). The reaction mixture was stirred at reflux for 2 h, cooled to room temperature, and filtered through Celite. The Celite was washed with methanol, and the combined filtrates were concentrated to yield 5-amino-2,4-di-tert-butyl-phenol as a grey solid (1.66 g, quant.).

5-AMino-2,4-di-tert-butylphenol Preparation Products And Raw materials

Raw materials

Preparation Products

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5-AMino-2,4-di-tert-butylphenol Suppliers

China 136 India 14 United States 4 Global 154

ShangHai Onsyn-Chemical Technology Co., Ltd.

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View Lastest Price from 5-AMino-2,4-di-tert-butylphenol manufacturers

Shaanxi Dideu New Materials Co. Ltd

Product: 5-AMino-2,4-di-tert-butylphenol 873055-58-4
Price: US $0.00-0.00/KG
Min. Order: 1KG
Purity: 98.0%
Supply Ability: 10000KGS
Release date: 2024-11-14

Career Henan Chemical Co

Product: 5-Amino-2,4-di-tert-butylphenol 873055-58-4
Price: US $100.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: Customized
Release date: 2018-07-26

873055-58-4, 5-AMino-2,4-di-tert-butylphenolRelated Search:

2,4-di-tert-butyl-5-nitrophenyl methyl carbonate 4-HYDROXY-QUINOLINE-3-CARBOXYLIC ACID METHYL ESTER Phenol, 2,4-bis(1,1-diMethylethyl)-5-nitro- 2-PHENYLAMINOMETHYLENE-MALONIC ACIDDIETHYL ESTER 4-OXO-1,4-DIHYDROQUINOLINE-3-CARBOXYLIC ACID VX-770

5-AMino-2,4-di-tert-butylphenol

2,4-Di-tert-butyl-5-aMinophenyl Methyl carbonate

Phenol, 5-amino-2,4-bis(1,1-dimethylethyl)-

4,6-dichloropyridazin-4-ol

5-Amino-2,4-ditertiarybutyphenol

5-Amino-2,4-bis(2-methyl-2-propanyl)phenol

VX-770 intermediate

5-amino-2,4-di-tert-butylphenol hydrochloride (base)

5-Amino-2,4-ditertiarybutylphenol

2,4-ditert-butyl-5-aminophenol

5-Amino-2,4-di-tert-butyl-phenol (Ivacaftor intermediate)

873055-58-4

973055-58-4