LCL-161

ChemicalBook > CAS DataBase List > LCL-161

Product Name: LCL-161
CAS No.: 1005342-46-0
Chemical Name: LCL-161
Synonyms: CS-987;LCL-161;LCL-161; LCL161;LCL-161 USP/EP/BP;LCL161, inhibitor of Apoptosis Protein (IAP) family of proteins;LCL161, 98%, inhibitor of Apoptosis Protein (IAP) family of proteins;(S)-N-((S)-1-Cyclohexyl-2-((S)-2-(4-(4-fluorobenzoyl)thiazol-2-yl)pyrrolidin-1-yl)-2-oxoethyl);N-[(1S)-1-Cyclohexyl-2-{(2S)-2-[4-(4-fluorobenzoyl)-1,3-thiazol-2-yl]-1-pyrrolidinyl}-2-oxoethyl]-N2-MethylalaninaMide;(2S)-N-[(1S)-1-Cyclohexyl-2-[(2S)-2-[4-(4-fluorobenzoyl)-2-thiazolyl]-1-pyrrolidinyl]-2-oxoethyl]-2-(methylamino)-propanamide;N-[(1S)-1-cyclohexyl-2-[(2S)-2-[4-(4-fluorobenzoyl)-2-thiazolyl]-1-pyrrolidinyl]-2-oxoethyl]-2-(methylamino)-(2S)-propanamide
CBNumber: CB62650157
Molecular Formula: C26H33FN4O3S
Formula Weight: 500.63
MOL File: 1005342-46-0.mol

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LCL-161 Property

Boiling point:: 713.7±60.0 °C(Predicted)
Density: 1.245±0.06 g/cm3(Predicted)
storage temp.: Store at -20°C
solubility: ≥25.05 mg/mL in DMSO; insoluble in H2O; insoluble in EtOH
form: solid
pka: 14.25±0.46(Predicted)

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Safety

RIDADR: 3077
HS Code: 29341000

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

Precautionary statements

P280Wear protective gloves/protective clothing/eye protection/face protection.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Cayman Chemical

Product number: 22420
Product name: LCL-161
Purity: ≥98%
Packaging: 5mg
Price: $160
Updated: 2024/03/01

Cayman Chemical

Product number: 22420
Product name: LCL-161
Purity: ≥98%
Packaging: 10mg
Price: $286
Updated: 2024/03/01

Cayman Chemical

Product number: 22420
Product name: LCL-161
Purity: ≥98%
Packaging: 25mg
Price: $515
Updated: 2024/03/01

Cayman Chemical

Product number: 22420
Product name: LCL-161
Purity: ≥98%
Packaging: 50mg
Price: $869
Updated: 2024/03/01

TRC

Product number: L270000
Product name: LCL161
Packaging: 25mg
Price: $475
Updated: 2021/12/16

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LCL-161 Chemical Properties,Usage,Production

Description

LCL-161 is a small molecule Smac mimetic that inhibits multiple inhibitor of apoptosis (IAP) family proteins.

Uses

LCL 161 is a second mitochondria-derived activator of caspases (SMAC) inhibitor used to prolong patient survival by increasing apoptosis of anti-tumor drugs.

LCL-161 Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from LCL-161 manufacturers

Career Henan Chemical Co

Product: N-[(1S)-1-Cyclohexyl-2-{(2S)-2-[4-(4-fluorobenzoyl)-1,3-thiazol-2-yl]-1-pyrrolidinyl}-2-oxoethyl]-N2-methylalaninamide 1005342-46-0
Price: US $1.00/KG
Min. Order: 1KG
Purity: Min98% HPLC
Supply Ability: g/kg/ton
Release date: 2019-12-30

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LCL-161

N-[(1S)-1-Cyclohexyl-2-{(2S)-2-[4-(4-fluorobenzoyl)-1,3-thiazol-2-yl]-1-pyrrolidinyl}-2-oxoethyl]-N2-MethylalaninaMide

(2S)-N-[(1S)-1-Cyclohexyl-2-[(2S)-2-[4-(4-fluorobenzoyl)-2-thiazolyl]-1-pyrrolidinyl]-2-oxoethyl]-2-(methylamino)-propanamide

(S)-N-((S)-1-Cyclohexyl-2-((S)-2-(4-(4-fluorobenzoyl)thiazol-2-yl)pyrrolidin-1-yl)-2-oxoethyl)

N-[(1S)-1-cyclohexyl-2-[(2S)-2-[4-(4-fluorobenzoyl)-2-thiazolyl]-1-pyrrolidinyl]-2-oxoethyl]-2-(methylamino)-(2S)-propanamide

(2S)-N-[(1S)-1-Cyclohexyl-2-[(2S)-2-[4-(4-fluorobenzoyl)-2-thiazolyl]-1-pyrrolidinyl]-2-oxoethyl]-2-(methylamino)-propanamide LCL 161

LCL161, 98%, inhibitor of Apoptosis Protein (IAP) family of proteins

CS-987

LCL-161; LCL161

Propanamide, N-[(1S)-1-cyclohexyl-2-[(2S)-2-[4-(4-fluorobenzoyl)-2-thiazolyl]-1-pyrrolidinyl]-2-oxoethyl]-2-(methylamino)-, (2S)-

LCL-161 USP/EP/BP

LCL161, inhibitor of Apoptosis Protein (IAP) family of proteins

1005342-46-0

C26H33FN4O3S

Inhibitors