ChemicalBook > CAS DataBase List > BenzenesulfonaMide, N-[1,6-dihydro-5-(2-Methoxyphenoxy)-6-oxo[2,2'-bipyriMidin]-4-yl]-4-(1,1-diMethylethyl)-

BenzenesulfonaMide, N-[1,6-dihydro-5-(2-Methoxyphenoxy)-6-oxo[2,2'-bipyriMidin]-4-yl]-4-(1,1-diMethylethyl)-

Product Name
BenzenesulfonaMide, N-[1,6-dihydro-5-(2-Methoxyphenoxy)-6-oxo[2,2'-bipyriMidin]-4-yl]-4-(1,1-diMethylethyl)-
CAS No.
174227-14-6
Chemical Name
BenzenesulfonaMide, N-[1,6-dihydro-5-(2-Methoxyphenoxy)-6-oxo[2,2'-bipyriMidin]-4-yl]-4-(1,1-diMethylethyl)-
Synonyms
Bosentan USP RC B;Bosentan IMpurity D;Bosentan EP Impurity-B;O-Deshydroxyethyl Bosentan;Bosentan Related CoMpound B;Bosentan USP Related Compound B;Bosentan Related Compound B (O-Deshydroxyethyl Bosentan);4-(tert-butyl)-N-(6-hydroxy-5-(2-methoxyphenoxy)-[2,2-bipyrimidin]-4-yl)benzenesulfonamide;p-tert-butyl-N-[6-(hydroxy)-5-(2-methoxyphenoxy)[2,2'-bipyrimidin]-4-yl]benzene sulfonamide;4-(tert-butyl)-N-(6-hydroxy-5-(2-methoxyphenoxy)-[2,2'-bipyrimidin]-4-yl)benzenesulfonamide
CBNumber
CB62667876
Molecular Formula
C25H25N5O5S
Formula Weight
507.56
MOL File
174227-14-6.mol
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BenzenesulfonaMide, N-[1,6-dihydro-5-(2-Methoxyphenoxy)-6-oxo[2,2'-bipyriMidin]-4-yl]-4-(1,1-diMethylethyl)- Property

Melting point:
>218°C (dec.)
Boiling point:
690.0±65.0 °C(Predicted)
Density 
1.34±0.1 g/cm3(Predicted)
storage temp. 
Refrigerator
solubility 
DMSO (Slightly), Chloroform (Slightly), Methanol (Slightly)
form 
Solid
pka
4.48±0.50(Predicted)
color 
Pale Beige to Light Beige
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Safety

HS Code 
2935909550
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P321Specific treatment (see … on this label).

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P362Take off contaminated clothing and wash before reuse.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
1076137
Product name
Bosentan Related Compound B
Purity
United States Pharmacopeia (USP) Reference Standard
Packaging
15mg
Price
$1300
Updated
2025/07/31
TRC
Product number
D290485
Product name
O-DeshydroxyethylBosentan
Packaging
500mg
Price
$1390
Updated
2021/12/16
Biosynth Carbosynth
Product number
FD64077
Product name
O-Deshydroxyethyl bosentan
Packaging
10mg
Price
$650
Updated
2021/12/16
Biosynth Carbosynth
Product number
FD64077
Product name
O-Deshydroxyethyl bosentan
Packaging
25mg
Price
$950
Updated
2021/12/16
Biosynth Carbosynth
Product number
FD64077
Product name
O-Deshydroxyethyl bosentan
Packaging
1mg
Price
$120
Updated
2021/12/16
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BenzenesulfonaMide, N-[1,6-dihydro-5-(2-Methoxyphenoxy)-6-oxo[2,2'-bipyriMidin]-4-yl]-4-(1,1-diMethylethyl)- Chemical Properties,Usage,Production

Uses

O-Deshydroxyethyl Bosentan (Bosentan USP Related Compound B) is an impurity of Bosentan (B675900); a mixed endothelin receptor antagonist. Used as a vasodilator and antihypertensive.

BenzenesulfonaMide, N-[1,6-dihydro-5-(2-Methoxyphenoxy)-6-oxo[2,2'-bipyriMidin]-4-yl]-4-(1,1-diMethylethyl)- Preparation Products And Raw materials

Raw materials

Preparation Products

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BenzenesulfonaMide, N-[1,6-dihydro-5-(2-Methoxyphenoxy)-6-oxo[2,2'-bipyriMidin]-4-yl]-4-(1,1-diMethylethyl)- Suppliers

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174227-14-6, BenzenesulfonaMide, N-[1,6-dihydro-5-(2-Methoxyphenoxy)-6-oxo[2,2'-bipyriMidin]-4-yl]-4-(1,1-diMethylethyl)-Related Search:

Bosentan Related Compound 4 4-tert-Butyl-N-(6-chloro-5-(2-methoxyphenoxy)-2,2'-bipyrimidin-4-yl)benzenesulfonamide 4-tert-Butylbenzenesulfonamide Bosentan Impurity 15 HCl 4,6-Dichloro-5-(2-methoxyphenoxy)-2,2'-bipyrimidine Bosentan Related Compound 5 Bosentan hydrate BenzenesulfonaMide, N,N'-[1,2-ethanediylbis[oxy[5-(2-Methoxyphenoxy)[2,2'-bipyriMidine]-6,4-diyl]]]bis[4-(1,1-diMethylethyl)- HYDROXY DESMETHYL BOSENTAN DESMETHYL BOSENTAN Hydroxy Bosentan

  • BenzenesulfonaMide, N-[1,6-dihydro-5-(2-Methoxyphenoxy)-6-oxo[2,2'-bipyriMidin]-4-yl]-4-(1,1-diMethylethyl)-
  • Bosentan USP Related Compound B
  • p-tert-butyl-N-[6-(hydroxy)-5-(2-methoxyphenoxy)[2,2'-bipyrimidin]-4-yl]benzene sulfonamide
  • Bosentan USP RC B
  • Bosentan IMpurity D
  • Bosentan Related CoMpound B
  • N-[1,6-Dihydro-5-(2-methoxyphenoxy)-6-oxo[2,2'-bipyrimidin]-4-yl]-4-(1,1-dimethylethyl)benzenesulfonamide
  • Bosentan Related Compound B (15 mg) (4-(tert-butyl)-N-[6-hydroxy-5-(2-methoxyphenoxy)-(2,2'-bipyrimidin)-4-yl]benzenesulfonamide)
  • O-Deshydroxyethyl Bosentan
  • Bosentan USP Related Compound B: 4-(tert-Butyl)-N-[6-hydroxy-5-(2-methoxyphenoxy)-(2,2'-bipyrimidin)-4-yl]benzenesulfonamide
  • 4-(tert-butyl)-N-(6-hydroxy-5-(2-methoxyphenoxy)-[2,2-bipyrimidin]-4-yl)benzenesulfonamide
  • Bosentan Related Compound B (O-Deshydroxyethyl Bosentan)
  • Bosentan Related Compound B (4-(tert-butyl)-N-[6-hydroxy-5-(2-methoxyphenoxy)-(2,2''-bipyrimidin)-4- (1076137)
  • 4-(tert-butyl)-N-(6-hydroxy-5-(2-methoxyphenoxy)-[2,2'-bipyrimidin]-4-yl)benzenesulfonamide
  • Bosentan EP Impurity-B
  • 174227-14-6
  • C25H25N5O5S