LUZINDOLE

Product Name: LUZINDOLE
CAS No.: 117946-91-5
Chemical Name: LUZINDOLE
Synonyms: N-0774;LUZINDOLE;Luzindole N;Luzindole Solution, 100ppm;N-ACETYL-2-BENZYLTRYPTAMINE;2-Benzyl-N-acetyltryptaMine;LuzindoleN-Acetyl-2-benzyltryptamine;N-(2-(2-benzyl-1H-indol-3-yl)ethyl)acetamide;n-[2-[2-(phenylmethyl)-1h-indol-3-yl]ethyl]acetamide;AcetaMide, N-[2-[2-(phenylMethyl)-1H-indol-3-yl]ethyl]-
CBNumber: CB6268781
Molecular Formula: C19H20N2O
Formula Weight: 292.37
MOL File: 117946-91-5.mol

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LUZINDOLE Property

Melting point:: 44-46°C
Boiling point:: 434.31°C (rough estimate)
Density: 1.1045 (rough estimate)
refractive index: 1.6140 (estimate)
storage temp.: -20°C
solubility: DMSO: 5 mg/mL
form: White to off-white crystalline solid.
pka: 16.36±0.46(Predicted)
color: Off-White to Yellow
Water Solubility: Soluble in DMSO (100 mM), ethanol (100 mM), chloroform, methanol, and water.
Stability:: Store at -20°C
CAS DataBase Reference: 117946-91-5(CAS DataBase Reference)

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Safety

Safety Statements: 24/25
WGK Germany: 3
RTECS: AC7765700
HS Code: 29339980

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: L2407
Product name: Luzindole
Purity: ≥90%
Packaging: 5mg
Price: $179
Updated: 2024/03/01

TCI Chemical

Product number: L0316
Product name: Luzindole
Purity: >98.0%(HPLC)
Packaging: 25mg
Price: $300
Updated: 2024/03/01

Alfa Aesar

Product number: J61915
Product name: Luzindole, 97%
Packaging: 5mg
Price: $125.65
Updated: 2024/03/01

Alfa Aesar

Product number: J61915
Product name: Luzindole, 97%
Packaging: 25mg
Price: $453
Updated: 2021/12/16

Cayman Chemical

Product number: 15998
Product name: Luzindole
Purity: ≥98%
Packaging: 5mg
Price: $62
Updated: 2024/03/01

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LUZINDOLE Chemical Properties,Usage,Production

Chemical Properties

Off-White Amorphous Solid

Uses

A melatonin receptor antagonist

Uses

Luzindole significantly antagonizes melatonin-mediated antinociception, suggesting that MEL-1B-R plays a further role as a mediator of melatonin modulation of pain signaling. It is used both in vitro and in vivo to evaluate the roles of melatonin receptor signaling in diverse pathways, including circadian rhythms, animal behavior, and melanophore response

Definition

ChEBI: A member of the class of indoles that is tryptamine in which one of the amino hydrogens is replaced by an acetyl group while the hydrogen at position 2 is replaced by a benzyl group.

Biological Activity

Melatonin antagonist.

Biochem/physiol Actions

Luzindole is a melatonin (mel) receptor antagonist. It has higher affinity towards the Mel 1b receptor than the Mel 1a receptor subtype.

storage

Store at -20°C

LUZINDOLE Preparation Products And Raw materials

Raw materials

Preparation Products

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LUZINDOLE Suppliers

Americas 1 Belgium 1 Canada 1 China 83 Europe 1 Germany 3 India 3 Japan 3 Switzerland 2 United Kingdom 6 United States 16 Global 120

J & K SCIENTIFIC LTD.

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3B Pharmachem (Wuhan) International Co.,Ltd.

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Chemsky（shanghai）International Co.,Ltd.

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Hangzhou Sage Chemical Co., Ltd.

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Thermo Fisher Scientific

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TOKYO CHEMICAL INDUSTRY CO., LTD.

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TCI Europe

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TCI AMERICA

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117946-91-5, LUZINDOLERelated Search:

N-Acetyl-D-galactosamine N-Acetylglycine Tadalafil 1-(1-PHENYL-1,3,4,9-TETRAHYDRO-BETA-CARBOLIN-2-YL)-ETHANONE LUZINDOLE TADALAFIL-METHYL-D3 1-[1-(4-NITRO-PHENYL)-1,3,4,9-TETRAHYDRO-BETA-CARBOLIN-2-YL]-ETHANONE 1-[1-(4-METHOXY-PHENYL)-1,3,4,9-TETRAHYDRO-BETA-CARBOLIN-2-YL]-ETHANONE CIS-1-(1,3-BENZODIOXOL-5-YL)-2-(CHLOROACETYL)-2,3,4,9-TETRAHYDRO-, 1H-PYRIDO[3,4-B]INDOLE-3-CARBOXYLIC ACID METHYL ESTER DH 97 Chloropretadalafil

LUZINDOLE

n-[2-[2-(phenylmethyl)-1h-indol-3-yl]ethyl]acetamide

N-[2-[2-(Phenylmethyl)-1H-indol-3-yl]ethyl]acetamide, N-Acetyl-2-benzyltryptamine

N-ACETYL-2-BENZYLTRYPTAMINE

N-0774

LuzindoleN-Acetyl-2-benzyltryptamine

N-(2-(2-benzyl-1H-indol-3-yl)ethyl)acetamide

2-Benzyl-N-acetyltryptaMine

AcetaMide, N-[2-[2-(phenylMethyl)-1H-indol-3-yl]ethyl]-

Luzindole Solution, 100ppm

Luzindole N

117946-91-5

Melatonin receptor

Aromatics Compounds

Aromatics