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LUZINDOLE

Product Name
LUZINDOLE
CAS No.
117946-91-5
Chemical Name
LUZINDOLE
Synonyms
N-0774;LUZINDOLE;Luzindole N;Luzindole Solution, 100ppm;N-ACETYL-2-BENZYLTRYPTAMINE;2-Benzyl-N-acetyltryptaMine;LuzindoleN-Acetyl-2-benzyltryptamine;N-(2-(2-benzyl-1H-indol-3-yl)ethyl)acetamide;n-[2-[2-(phenylmethyl)-1h-indol-3-yl]ethyl]acetamide;AcetaMide, N-[2-[2-(phenylMethyl)-1H-indol-3-yl]ethyl]-
CBNumber
CB6268781
Molecular Formula
C19H20N2O
Formula Weight
292.37
MOL File
117946-91-5.mol
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LUZINDOLE Property

Melting point:
44-46°C
Boiling point:
434.31°C (rough estimate)
Density 
1.1045 (rough estimate)
refractive index 
1.6140 (estimate)
storage temp. 
-20°C
solubility 
DMSO: 5 mg/mL
form 
White to off-white crystalline solid.
pka
16.36±0.46(Predicted)
color 
Off-White to Yellow
Water Solubility 
Soluble in DMSO (100 mM), ethanol (100 mM), chloroform, methanol, and water.
Stability:
Store at -20°C
CAS DataBase Reference
117946-91-5(CAS DataBase Reference)
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Safety

Safety Statements 
24/25
WGK Germany 
3
RTECS 
AC7765700
HS Code 
29339980
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
L2407
Product name
Luzindole
Purity
≥90%
Packaging
5mg
Price
$179
Updated
2024/03/01
TCI Chemical
Product number
L0316
Product name
Luzindole
Purity
>98.0%(HPLC)
Packaging
25mg
Price
$300
Updated
2024/03/01
Alfa Aesar
Product number
J61915
Product name
Luzindole, 97%
Packaging
5mg
Price
$125.65
Updated
2024/03/01
Alfa Aesar
Product number
J61915
Product name
Luzindole, 97%
Packaging
25mg
Price
$453
Updated
2021/12/16
Cayman Chemical
Product number
15998
Product name
Luzindole
Purity
≥98%
Packaging
5mg
Price
$62
Updated
2024/03/01
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LUZINDOLE Chemical Properties,Usage,Production

Chemical Properties

Off-White Amorphous Solid

Uses

A melatonin receptor antagonist

Uses

Luzindole significantly antagonizes melatonin-mediated antinociception, suggesting that MEL-1B-R plays a further role as a mediator of melatonin modulation of pain signaling. It is used both in vitro and in vivo to evaluate the roles of melatonin receptor signaling in diverse pathways, including circadian rhythms, animal behavior, and melanophore response

Definition

ChEBI: A member of the class of indoles that is tryptamine in which one of the amino hydrogens is replaced by an acetyl group while the hydrogen at position 2 is replaced by a benzyl group.

Biological Activity

Melatonin antagonist.

Biochem/physiol Actions

Luzindole is a melatonin (mel) receptor antagonist. It has higher affinity towards the Mel 1b receptor than the Mel 1a receptor subtype.

storage

Store at -20°C

LUZINDOLE Preparation Products And Raw materials

Raw materials

Preparation Products

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LUZINDOLE Suppliers

SIGMA-RBI
Tel
--
Fax
--
Country
Switzerland
ProdList
6896
Advantage
91
Alexis Corporation
Tel
--
Fax
--
Email
alexis-ch@alexis-corp.ch
Country
Switzerland
ProdList
3599
Advantage
74

117946-91-5, LUZINDOLERelated Search:


  • LUZINDOLE
  • n-[2-[2-(phenylmethyl)-1h-indol-3-yl]ethyl]acetamide
  • N-[2-[2-(Phenylmethyl)-1H-indol-3-yl]ethyl]acetamide, N-Acetyl-2-benzyltryptamine
  • N-ACETYL-2-BENZYLTRYPTAMINE
  • N-0774
  • LuzindoleN-Acetyl-2-benzyltryptamine
  • N-(2-(2-benzyl-1H-indol-3-yl)ethyl)acetamide
  • 2-Benzyl-N-acetyltryptaMine
  • AcetaMide, N-[2-[2-(phenylMethyl)-1H-indol-3-yl]ethyl]-
  • Luzindole Solution, 100ppm
  • Luzindole N
  • 117946-91-5
  • Melatonin receptor
  • Aromatics Compounds
  • Aromatics