2-HYDROXY-3-METHOXY-5-NITROBENZALDEHYDE
- Product Name
- 2-HYDROXY-3-METHOXY-5-NITROBENZALDEHYDE
- CAS No.
- 17028-61-4
- Chemical Name
- 2-HYDROXY-3-METHOXY-5-NITROBENZALDEHYDE
- Synonyms
- NSC 206206;AKOS B029200;5-NITRO-O-VANILLIN;5-Nitro orthovanilin;5-Nitro-orthovanillin;Entacapone Impurity 89;2-HYDROXY-5-NITRO-M-ANI;3-METHOXY-5-NITROSALICYLADEHYDE;3-METHOXY-5-NITROSALICYLALDEHYDE;2-HYDROXY-5-NITRO-M-ANISALDEHYDE
- CBNumber
- CB6269915
- Molecular Formula
- C8H7NO5
- Formula Weight
- 197.14
- MOL File
- 17028-61-4.mol
2-HYDROXY-3-METHOXY-5-NITROBENZALDEHYDE Property
- Melting point:
- 141-143 °C (lit.)
- Boiling point:
- 344.0±42.0 °C(Predicted)
- Density
- 1.456
- storage temp.
- under inert gas (nitrogen or Argon) at 2-8°C
- form
- powder to crystal
- pka
- 5.08±0.44(Predicted)
- color
- Light orange to Yellow to Green
- Water Solubility
- Slightly soluble in water.
- Sensitive
- Air Sensitive
- BRN
- 613271
- CAS DataBase Reference
- 17028-61-4(CAS DataBase Reference)
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P271Use only outdoors or in a well-ventilated area.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- 434086
- Product name
- 3-Methoxy-5-nitrosalicylaldehyde
- Purity
- 98%
- Packaging
- 5g
- Price
- $183.35
- Updated
- 2025/07/31
- Product number
- H0397
- Product name
- 2-Hydroxy-5-nitro-m-anisaldehyde
- Purity
- >99.0%(GC)(T)
- Packaging
- 5g
- Price
- $75
- Updated
- 2025/07/31
- Product number
- H999858
- Product name
- 2-Hydroxy-3-methoxy-5-nitrobenzaldehyde
- Packaging
- 50mg
- Price
- $45
- Updated
- 2021/12/16
- Product number
- H999858
- Product name
- 2-Hydroxy-3-methoxy-5-nitrobenzaldehyde
- Packaging
- 500mg
- Price
- $75
- Updated
- 2021/12/16
- Product number
- 5487AD
- Product name
- 2-Hydroxy-3-methoxy-5-nitrobenzaldehyde
- Packaging
- 25g
- Price
- $214
- Updated
- 2021/12/16
2-HYDROXY-3-METHOXY-5-NITROBENZALDEHYDE Chemical Properties,Usage,Production
Uses
2-Hydroxy-3-methoxy-5-nitrobenzaldehyde is used for the syntheses of zinc-selective spiropyran-based fluorescent and photoregenerable receptor, (E)-2,4-dihydroxy-N?-(2-hydroxy-3-methoxy-5-nitrobenzylidene)benzohydrazide dihydrate, ethyl 4-(8-methoxy-3?,3?-dimethyl-6-nitrospiro[chromene-2,2?-indoline]-1?-yl)butanoate and 1-(3-carbomethoxypropyl)-3-3-dimethyl-8-methoxy-6-nitrospiro[2H-1]-benzopyran-2,2-indoline.
Synthesis
148-53-8
17028-61-4
General procedure for the synthesis of 2-hydroxy-3-methoxy-5-nitrobenzaldehyde from o-vanillin: o-vanillin (94 mg, 1 mmol) was dissolved in 3 mL of glacial acetic acid in a 50 mL test tube. Subsequently, solid Y(NO3)3-6H2O (383 mg, 1 mmol) was added to the solution and the reaction mixture was shaken continuously for 10 min at room temperature. The reaction process was monitored by thin layer chromatography (TLC) and the unfolding agent was petroleum ether with 10% ethyl acetate. Upon completion of the reaction, 30 mL of ice-cold water was added to the reaction mixture and allowed to stand for 15 min. The precipitated solid product was collected by filtration and washed with cold water. The solid product obtained was used directly for analysis without further purification. Detailed experimental methods for the synthesis of compounds 2a-2e are described in Supporting Information.
References
[1] Journal of Chemical Sciences, 2017, vol. 129, # 1, p. 39 - 43
[2] Journal of Materials Chemistry C, 2018, vol. 6, # 43, p. 11536 - 11551
[3] Dyes and Pigments, 2017, vol. 136, p. 292 - 301
[4] Proceedings of the National Institute of Sciences of India, 1940, vol. 6, p. 641,656
[5] Justus Liebigs Annalen der Chemie, 1932, vol. 496, p. 125,140
2-HYDROXY-3-METHOXY-5-NITROBENZALDEHYDE Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from 2-HYDROXY-3-METHOXY-5-NITROBENZALDEHYDE manufacturers
- Product
- 2-HYDROXY-3-METHOXY-5-NITROBENZALDEHYDE 17028-61-4
- Price
- US $1.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 200kg
- Release date
- 2019-12-25