ChemicalBook > CAS DataBase List > 2-HYDROXY-3-METHOXY-5-NITROBENZALDEHYDE

2-HYDROXY-3-METHOXY-5-NITROBENZALDEHYDE

Product Name: 2-HYDROXY-3-METHOXY-5-NITROBENZALDEHYDE
CAS No.: 17028-61-4
Chemical Name: 2-HYDROXY-3-METHOXY-5-NITROBENZALDEHYDE
Synonyms: NSC 206206;AKOS B029200;5-NITRO-O-VANILLIN;5-Nitro orthovanilin;5-Nitro-orthovanillin;Entacapone Impurity 89;2-HYDROXY-5-NITRO-M-ANI;3-METHOXY-5-NITROSALICYLADEHYDE;3-METHOXY-5-NITROSALICYLALDEHYDE;2-HYDROXY-5-NITRO-M-ANISALDEHYDE
CBNumber: CB6269915
Molecular Formula: C8H7NO5
Formula Weight: 197.14
MOL File: 17028-61-4.mol

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2-HYDROXY-3-METHOXY-5-NITROBENZALDEHYDE Property

Melting point:: 141-143 °C (lit.)
Boiling point:: 344.0±42.0 °C(Predicted)
Density: 1.456
storage temp.: under inert gas (nitrogen or Argon) at 2-8°C
form: powder to crystal
pka: 5.08±0.44(Predicted)
color: Light orange to Yellow to Green
Water Solubility: Slightly soluble in water.
Sensitive: Air Sensitive
BRN: 613271
CAS DataBase Reference: 17028-61-4(CAS DataBase Reference)

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Safety

Hazard Codes: Xi
Risk Statements: 36/37/38
Safety Statements: 26-36
WGK Germany: 3
HS Code: 2913.00.4000
HazardClass: IRRITANT

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 434086
Product name: 3-Methoxy-5-nitrosalicylaldehyde
Purity: 98%
Packaging: 5g
Price: $183.35
Updated: 2025/07/31

TCI Chemical

Product number: H0397
Product name: 2-Hydroxy-5-nitro-m-anisaldehyde
Purity: >99.0%(GC)(T)
Packaging: 5g
Price: $75
Updated: 2025/07/31

TRC

Product number: H999858
Product name: 2-Hydroxy-3-methoxy-5-nitrobenzaldehyde
Packaging: 50mg
Price: $45
Updated: 2021/12/16

TRC

Product number: H999858
Product name: 2-Hydroxy-3-methoxy-5-nitrobenzaldehyde
Packaging: 500mg
Price: $75
Updated: 2021/12/16

AK Scientific

Product number: 5487AD
Product name: 2-Hydroxy-3-methoxy-5-nitrobenzaldehyde
Packaging: 25g
Price: $214
Updated: 2021/12/16

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2-HYDROXY-3-METHOXY-5-NITROBENZALDEHYDE Chemical Properties,Usage,Production

Uses

2-Hydroxy-3-methoxy-5-nitrobenzaldehyde is used for the syntheses of zinc-selective spiropyran-based fluorescent and photoregenerable receptor, (E)-2,4-dihydroxy-N?-(2-hydroxy-3-methoxy-5-nitrobenzylidene)benzohydrazide dihydrate, ethyl 4-(8-methoxy-3?,3?-dimethyl-6-nitrospiro[chromene-2,2?-indoline]-1?-yl)butanoate and 1-(3-carbomethoxypropyl)-3-3-dimethyl-8-methoxy-6-nitrospiro[2H-1]-benzopyran-2,2-indoline.

Synthesis

148-53-8

17028-61-4

General procedure for the synthesis of 2-hydroxy-3-methoxy-5-nitrobenzaldehyde from o-vanillin: o-vanillin (94 mg, 1 mmol) was dissolved in 3 mL of glacial acetic acid in a 50 mL test tube. Subsequently, solid Y(NO3)3-6H2O (383 mg, 1 mmol) was added to the solution and the reaction mixture was shaken continuously for 10 min at room temperature. The reaction process was monitored by thin layer chromatography (TLC) and the unfolding agent was petroleum ether with 10% ethyl acetate. Upon completion of the reaction, 30 mL of ice-cold water was added to the reaction mixture and allowed to stand for 15 min. The precipitated solid product was collected by filtration and washed with cold water. The solid product obtained was used directly for analysis without further purification. Detailed experimental methods for the synthesis of compounds 2a-2e are described in Supporting Information.

References

[1] Journal of Chemical Sciences, 2017, vol. 129, # 1, p. 39 - 43
[2] Journal of Materials Chemistry C, 2018, vol. 6, # 43, p. 11536 - 11551
[3] Dyes and Pigments, 2017, vol. 136, p. 292 - 301
[4] Proceedings of the National Institute of Sciences of India, 1940, vol. 6, p. 641,656
[5] Justus Liebigs Annalen der Chemie, 1932, vol. 496, p. 125,140

2-HYDROXY-3-METHOXY-5-NITROBENZALDEHYDE Preparation Products And Raw materials

Raw materials

Preparation Products

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2-HYDROXY-3-METHOXY-5-NITROBENZALDEHYDE Suppliers

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View Lastest Price from 2-HYDROXY-3-METHOXY-5-NITROBENZALDEHYDE manufacturers

Career Henan Chemical Co

Product: 2-HYDROXY-3-METHOXY-5-NITROBENZALDEHYDE 17028-61-4
Price: US $1.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 200kg
Release date: 2019-12-25

17028-61-4, 2-HYDROXY-3-METHOXY-5-NITROBENZALDEHYDERelated Search:

2-HYDROXY-3-METHOXY-5-NITROBENZALDEHYDE 4-HYDROXY-3-METHOXY-5-NITROBENZALDEHYDE 2-HYDROXY-5-METHOXY-3-NITRO-BENZALDEHYDE 5-Nitrosalicylaldehyde 3-METHOXY-5-NITROBENZALDEHYDE 2-BROMO-5,6-DIMETHOXY-3-NITRO-BENZALDEHYDE CHEMBRDG-BB 6742514 CHEMBRDG-BB 6744545 2,3-dimethoxy-5-nitro-benzaldehyde 4-HYDROXY-3-METHOXY-2-NITROBENZALDEHYDE 3-hydroxy-4-methoxy-5-nitrobenzaldehyde 4-HYDROXY-5-METHOXY-2-NITROBENZALDEHYDE 4-HYDROXY-3-METHOXY-5-NITROBENZALDEHYDE OXIME 2-HYDROXY-3-METHOXY-5-NITROBENZALDEHYDE OXIME 2-HYDROXY-5-METHOXY-3-NITROBENZALDEHYDE OXIME RARECHEM AL BE 0234 AKOS 227-94 3-ETHOXY-2-HYDROXY-5-NITROBENZALDEHYDE

2-HYDROXY-3-METHOXY-5-NITROBENZALDEHYDE 98%

benzaldehyde, 2-hydroxy-3-methoxy-5-nitro-

2-Hydroxy-3-methoxy-5-nitrobenzaldehyde 3-Methoxy-5-nitrosalicylaldehyde 5-Nitro-o-vanillin

5-NITRO-O-VANILLIN

AKOS B029200

3-METHOXY-5-NITROSALICYLADEHYDE

3-METHOXY-5-NITROSALICYLALDEHYDE

2-HYDROXY-3-METHOXY-5-NITROBENZALDEHYDE

2-HYDROXY-5-NITRO-3-METHOXYBENZALDEHYDE

2-HYDROXY-5-NITRO-M-ANISALDEHYDE

5-Nitro orthovanilin

5-Nitro-orthovanillin

2-formyl-6-methoxy-4-nitrophenolate

2-HYDROXY-5-NITRO-M-ANI

NSC 206206

2-Hydroxy-5-nitro-<i>M</i>-anisaldehyde

2-Hydroxy-5-nitro-m-anisaldehyde&gt

Entacapone Impurity 89

2-hydroxy-3-methoxy-5-nitro-benzaldehyde - [H83579]

17028-61-4

CH3OC6H2NO22OHCHO

ALDEHYDE

Building Blocks

Aldehydes

Carbonyl Compounds

Organic Building Blocks

Aromatic Aldehydes & Derivatives (substituted)

Aldehydes

Carbonyl Compounds