3-Cyanophenol
- Product Name
- 3-Cyanophenol
- CAS No.
- 873-62-1
- Chemical Name
- 3-Cyanophenol
- Synonyms
- 3-HYDROXYBENZONITRILE;Benzonitrile, 3-hydroxy-;AKOS B004111;M-CYANOPHENOL;3-CYANOPHENOL;3-Cyanophenol>3-Cyanophenol,97%;3-CYANOPHENOL 97%;3-Cyanophenol ,99%;M-HYDROXYBENZONITRILE
- CBNumber
- CB6270283
- Molecular Formula
- C7H5NO
- Formula Weight
- 119.12
- MOL File
- 873-62-1.mol
3-Cyanophenol Property
- Melting point:
- 78-81 °C(lit.)
- Boiling point:
- 222.38°C (rough estimate)
- Density
- 1.1871 (rough estimate)
- refractive index
- 1.5800 (estimate)
- storage temp.
- Inert atmosphere,Room Temperature
- form
- Crystalline Powder
- pka
- 8.61(at 25℃)
- color
- Almost white to light brown
- Water Solubility
- Slightly soluble in water.
- BRN
- 2041515
- InChI
- InChI=1S/C7H5NO/c8-5-6-2-1-3-7(9)4-6/h1-4,9H
- InChIKey
- SGHBRHKBCLLVCI-UHFFFAOYSA-N
- SMILES
- C(#N)C1=CC=CC(O)=C1
- CAS DataBase Reference
- 873-62-1(CAS DataBase Reference)
- NIST Chemistry Reference
- 3-Hydroxybenzoic acid nitrile(873-62-1)
Safety
- Hazard Codes
- Xn
- Risk Statements
- 22-36/37/38-20/21/22
- Safety Statements
- 26-36-45-36/37/39
- RIDADR
- 3276
- WGK Germany
- 2
- Hazard Note
- Harmful
- HazardClass
- 6.1
- PackingGroup
- III
- HS Code
- 29089990
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P270Do not eat, drink or smoke when using this product.
P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- C93800
- Product name
- 3-Cyanophenol
- Purity
- 99%
- Packaging
- 5g
- Price
- $107
- Updated
- 2025/07/31
- Product number
- C93800
- Product name
- 3-Cyanophenol
- Purity
- 99%
- Packaging
- 10g
- Price
- $161
- Updated
- 2023/06/20
- Product number
- C1583
- Product name
- 3-Cyanophenol
- Purity
- >98.0%(GC)
- Packaging
- 5g
- Price
- $48
- Updated
- 2025/07/31
- Product number
- C1583
- Product name
- 3-Cyanophenol
- Purity
- >98.0%(GC)
- Packaging
- 25g
- Price
- $148
- Updated
- 2025/07/31
- Product number
- H808495
- Product name
- 3-Hydroxybenzonitrile
- Packaging
- 25g
- Price
- $325
- Updated
- 2021/12/16
3-Cyanophenol Chemical Properties,Usage,Production
Chemical Properties
ALMOST WHITE TO LIGHT BROWN CRYSTALLINE POWDER
Uses
3-Hydroxybenzonitrile, is an intermediate that can be used for the synthesis of new Serotonin 5-HT1A receptor agonists having antinociceptive activity in vivo.
Synthesis
150255-96-2
873-62-1
The general procedure for the synthesis of 3-hydroxybenzonitrile from 3-cyanophenylboronic acid was as follows: arylboronic acid (1 mmol), 30% H2O2 aqueous solution (0.2 mL), ZnO nanocatalyst (5 mol%, sample ZnO-1), and 2 mL of water were mixed with stirring in a 50 mL round bottom flask at room temperature and under aerobic conditions. The reaction process was monitored by thin layer chromatography (TLC). Upon completion of the reaction, the reaction mixture was diluted with 20 mL of water and extracted with diethyl ether (3 x 20 mL). The organic layers were combined, washed with brine and dried over Na2SO4. Subsequently, the solvent was removed under reduced pressure in a rotary evaporator. The crude product was purified by silica gel (100-200 mesh) column chromatography (eluent: hexane/ethyl acetate, 9:1) to afford the target product 3-hydroxybenzonitrile. The structure of the product was confirmed by 1H NMR and 13C NMR.
References
[1] Journal of Organic Chemistry, 2017, vol. 82, # 10, p. 5236 - 5241
[2] Advanced Synthesis and Catalysis, 2018, vol. 360, # 10, p. 2013 - 2019
[3] Applied Catalysis A: General, 2018, vol. 562, p. 58 - 66
[4] Tetrahedron Letters, 2016, vol. 57, # 36, p. 4050 - 4052
[5] Tetrahedron Letters, 2015, vol. 56, # 14, p. 1780 - 1783
3-Cyanophenol Preparation Products And Raw materials
Raw materials
Preparation Products
3-Cyanophenol Suppliers
- Tel
- --
- Fax
- --
- y.barysheva@ukrorgsynth.com
- Country
- Ukraine
- ProdList
- 6230
- Advantage
- 38
View Lastest Price from 3-Cyanophenol manufacturers
- Product
- 3-Cyanophenol 873-62-1
- Price
- US $35.00/kg
- Min. Order
- 1kg
- Purity
- 99%
- Supply Ability
- 5000kg/week
- Release date
- 2024-05-29
- Product
- 3-cyanophenol 873-62-1
- Price
- US $0.00-0.00/Kg
- Min. Order
- 1Kg
- Purity
- 99.9%
- Supply Ability
- 200tons
- Release date
- 2024-04-09
- Product
- 3-Cyanophenol 873-62-1
- Price
- US $0.00/KG
- Min. Order
- 1KG
- Purity
- 98.5%
- Supply Ability
- 100 tons
- Release date
- 2022-02-18