2,3,4-Trimethoxybenzoic acid
- Product Name
- 2,3,4-Trimethoxybenzoic acid
- CAS No.
- 573-11-5
- Chemical Name
- 2,3,4-Trimethoxybenzoic acid
- Synonyms
- AKOS 214-77;RARECHEM AL BO 0027;LABOTEST-BB LT00454915;2,3,4-Trimethoxybenzoic;Trimetazidine Impurity L;2,3,4-trimethoxybenzoate;Trimetazidine Impurity 4;Trimetazidine Impurity 19;2,3,4-TRIMETHOXYBENZOIC ACID;Benzoic acid, 2,3,4-trimethoxy-
- CBNumber
- CB6271442
- Molecular Formula
- C10H12O5
- Formula Weight
- 212.2
- MOL File
- 573-11-5.mol
2,3,4-Trimethoxybenzoic acid Property
- Melting point:
- 99-102 °C (lit.)
- Boiling point:
- 312.03°C (rough estimate)
- Density
- 1.3006 (rough estimate)
- refractive index
- 1.5140 (estimate)
- storage temp.
- Sealed in dry,Room Temperature
- form
- Crystalline Powder
- pka
- 4.24±0.10(Predicted)
- color
- White to off-white
- BRN
- 2696073
- CAS DataBase Reference
- 573-11-5(CAS DataBase Reference)
- NIST Chemistry Reference
- 2,3,4-Trimethoxybenzoic acid(573-11-5)
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P405Store locked up.
N-Bromosuccinimide Price
- Product number
- 189790
- Product name
- 2,3,4-Trimethoxybenzoic acid
- Purity
- ≥98%
- Packaging
- 25g
- Price
- $34
- Updated
- 2023/06/20
- Product number
- T1116
- Product name
- 2,3,4-Trimethoxybenzoic Acid
- Purity
- >98.0%(GC)(T)
- Packaging
- 5g
- Price
- $60
- Updated
- 2025/07/31
- Product number
- T1116
- Product name
- 2,3,4-Trimethoxybenzoic Acid
- Purity
- >98.0%(GC)(T)
- Packaging
- 25g
- Price
- $166
- Updated
- 2025/07/31
- Product number
- T895728
- Product name
- 2,3,4-Trimethoxybenzoic Acid
- Packaging
- 5g
- Price
- $60
- Updated
- 2021/12/16
- Product number
- 2621-1-54
- Product name
- 2,3,4-Trimethoxybenzoic acid
- Purity
- 98%
- Packaging
- 100g
- Price
- $92
- Updated
- 2021/12/16
2,3,4-Trimethoxybenzoic acid Chemical Properties,Usage,Production
Chemical Properties
WHITE TO OFF-WHITE CRYSTALLINE POWDER
Uses
2,3,4-Trimethoxybenzoic acid was used in the synthesis of tropoloisoquinoline alkaloid pareitropone. It was also used in the synthesis of isomeric tris(pyrogallol) derivatives and naphthoic acid.
Synthesis
2103-57-3
573-11-5
General procedure for the synthesis of 2,3,4-trimethoxybenzoic acid from 2,3,4-trimethoxybenzaldehyde: To a stirred solution of 2,3,4-trimethoxybenzaldehyde (24.4 g, 124.4 mmol) in methanol (200 mL) was added an aqueous 50% potassium hydroxide solution (KOH, 22.4 g). The mixture was then heated to reflux. A 30% hydrogen peroxide solution (180 mL) was added dropwise over 30 minutes and the mixture was continued to reflux for 8 hours. After the oxidation reaction was complete, the reaction mixture was cooled and sodium bisulfite (NaHSO3) was added. Methanol was removed by distillation under reduced pressure and the resulting solution was acidified to acidity with concentrated hydrochloric acid. The precipitated 2,3,4-trimethoxybenzoic acid (25.0 g, 95% yield) was collected by filtration.
References
[1] Bioorganic and Medicinal Chemistry, 2014, vol. 22, # 9, p. 2671 - 2677
[2] Tetrahedron Letters, 2008, vol. 49, # 6, p. 1083 - 1086
[3] Helvetica Chimica Acta, 1924, vol. 7, p. 362
[4] Synthetic Communications, 2006, vol. 36, # 5, p. 679 - 683
2,3,4-Trimethoxybenzoic acid Preparation Products And Raw materials
Raw materials
Preparation Products
2,3,4-Trimethoxybenzoic acid Suppliers
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View Lastest Price from 2,3,4-Trimethoxybenzoic acid manufacturers
- Product
- 2,3,4-Trimethoxybenzoic acid 573-11-5
- Price
- US $10.00/kg
- Min. Order
- 1kg
- Purity
- 99%
- Supply Ability
- 20 ton
- Release date
- 2024-12-24
- Product
- 2,3,4-Trimethoxybenzoic acid 573-11-5
- Price
- US $1.00/kg
- Min. Order
- 1kg
- Purity
- 98%min
- Supply Ability
- 20tons
- Release date
- 2023-09-06
- Product
- 2,3,4-Trimethoxybenzoic acid 573-11-5
- Price
- US $1.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 1ton
- Release date
- 2019-07-11