UM729
- Product Name
- UM729
- CAS No.
- 1448723-60-1
- Chemical Name
- UM729
- Synonyms
- C07;UM729;CS-1240;UM-729;UM 729;UM729 USP/EP/BP;methyl 4-(3-(piperidin-1-yl)propylamino)-9H-pyrimido[4,5-b]indole-7-carboxylate;4-[[3-(1-Piperidinyl)propyl]amino]-9H-pyrimido[4,5-b]indole-7-carboxylic acid methyl ester;9H-Pyrimido[4,5-b]indole-7-carboxylic acid, 4-[[3-(1-piperidinyl)propyl]amino]-, methyl ester
- CBNumber
- CB62715674
- Molecular Formula
- C20H25N5O2
- Formula Weight
- 367.44
- MOL File
- 1448723-60-1.mol
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- orb612002
- Product name
- UM729
- Purity
- >98%
- Packaging
- 100mg
- Price
- $912.9
- Updated
- 2021/12/16
- Product number
- orb612002
- Product name
- UM729
- Purity
- >98%
- Packaging
- 250mg
- Price
- $1654.1
- Updated
- 2021/12/16
- Product number
- orb612002
- Product name
- UM729
- Purity
- >98%
- Packaging
- 1g
- Price
- $3432.3
- Updated
- 2021/12/16
- Product number
- DC8141
- Product name
- UM729
- Purity
- >98%
- Packaging
- 1g
- Price
- $2300
- Updated
- 2021/12/16
- Product number
- DC8141
- Product name
- UM729
- Purity
- >98%
- Packaging
- 250mg
- Price
- $1100
- Updated
- 2021/12/16
UM729 Chemical Properties,Usage,Production
Biological Activity
UM729 is an enhancer of aryl hydrocarbon receptor (AhR) antagonists.
in vitro
um729 expands normal hematopoietic stem and progenitor cells (HSPC) in an AhR-independent manner, and UM729 inhibits AML cell differentiation. In 05H163 cells, the addition of UM729 increased CD34+CD15- Number of cells. It can inhibit the differentiation of most AML cells in combination with AhR antagonists.
in vivo
In NSG mice, UM729, alone or in combination with SR1, enhanced engraftment but not leukemia stem cell (LSC) frequency distribution.
UM729 Preparation Products And Raw materials
Raw materials
Preparation Products
UM729 Suppliers
- Tel
- Fax
- 86-21-57758967
- sales@boylechem.com
- Country
- China
- ProdList
- 2923
- Advantage
- 55
- Tel
- +86-21-5821 5861
- Fax
- +86-21-5106 2861
- sales@letopharm.com
- Country
- China
- ProdList
- 2384
- Advantage
- 58
- Tel
- Fax
- -
- eric_feng1954@126.com
- Country
- China
- ProdList
- 9254
- Advantage
- 55
- Tel
- 857-239-0968
- Fax
- 857-239-8801
- service1@targetmol.com
- Country
- United States
- ProdList
- 2559
- Advantage
- 60
- Tel
- 21-31433387 15618786686
- Fax
- QQ:1369748377
- sales@rechemscience.com
- Country
- China
- ProdList
- 2985
- Advantage
- 58
- Tel
- 0519-83246372 13585352506
- Fax
- 0519-83246372
- Country
- China
- ProdList
- 1844
- Advantage
- 58
- Tel
- +86 18721201413
- Fax
- +86 (21) 5775-8967
- sales@biopharmaleader.com
- Country
- China
- ProdList
- 1720
- Advantage
- 58
- Tel
- 0571-85361029
- Fax
- 0571-85361029
- synstar518@163.com
- Country
- China
- ProdList
- 1991
- Advantage
- 58
- Tel
- +86-29-89586680 +86-15129568250
- 1026@dideu.com
- Country
- China
- ProdList
- 28761
- Advantage
- 58
- Tel
- +86-0371-86658258 15093356674;
- Fax
- 0371-86658258
- laboratory@coreychem.com
- Country
- China
- ProdList
- 30255
- Advantage
- 58
View Lastest Price from UM729 manufacturers
- Product
- UM729 1448723-60-1
- Price
- US $0.00-0.00/KG
- Min. Order
- 5mg
- Purity
- 99%
- Supply Ability
- 2000tons
- Release date
- 2019-12-31